AZUMA TOSHIFUMI

アズマトシフミ | AZUMA TOSHIFUMI

Affiliation and department：
Job title：教授

Research field (5)： Developmental biology , Genomics , Cell biology , Molecular biology , Medical biochemistry

Research keywords (6)： Nuclear membrane protein , Cell differentiation , Bone , Chromosome , Regeneration , iPS cell

Research theme for competitive and other funds (17)：

2023 - 2026 Exploration of a treatment for Hajdu-Cheney syndrome by Drug Repositioning using disease-specific iPS cells.
2021 - 2024 機能ゲノミクス解析とハイスループット解析を用いた線維性異形成症新規治療法開発
2020 - 2023 Identification of novel dental pulp stem cells and analysis of their regulatory mechanisms of differentiation
2020 - 2023 FGF23産生機序とリン代謝異常を基軸とする顎骨線維性骨異形成症の包括的病態理解
2020 - 2023 Hajdu-Cheney症候群特異的iPS細胞を用いた病態解明と治療法の開発

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Papers (98)：

Haruka Nakazato, Shoko Onodera, Natsuko Aida, Masahiro Furusawa, Toshifumi Azuma. Comprehensive analysis of transcription factors involved in odontoblast differentiation mechanism. Medical molecular morphology. 2024
Hiroyuki Ogura, Takashi Nakamura, Takenobu Ishii, Akiko Saito, Shoko Onodera, Akira Yamaguchi, Yasushi Nishii, Toshifumi Azuma. Mechanical stress-induced FGF-2 promotes proliferation and consequently induces osteoblast differentiation in mesenchymal stem cells. Biochemical and biophysical research communications. 2023. 684. 149145-149145
Natsuko Aida, Akiko Saito, Toshifumi Azuma. Current Status of Next-Generation Sequencing in Bone Genetic Diseases. International journal of molecular sciences. 2023. 24. 18
Shoko Onodera, Toshifumi Azuma. Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations. International journal of molecular sciences. 2023. 24. 16
間奈津子, 大野建州, 齋藤暁子, 加藤宏, 小野寺晶子, 東俊文. NOTCH2遺伝子変異を伴うHajdu-Cheney症候群疾患特異的iPS細胞を用いた破骨細胞分化誘導. 日本骨代謝学会学術集会プログラム抄録集. 2023. 41回. 162-162

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MISC (48)：

秀島樹, 中村ゆり子, 小野寺晶子, 森田奈那, 森田奈那, 野村武史, 高野正行, 東俊文, 片倉朗. Gorlin症候群診断遺伝子パネルを用いた顎骨嚢胞の遺伝子変異解析. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
千代侑香, 一戸達也, 東俊文, 大野建州. 18kDa Translocator protein(TSPO)のT細胞依存的免疫応答における役割解析(T cell-dependent regulatory roles of 18-kDa Translocator protein(TSPO)). Journal of Oral Biosciences Supplement. 2022. 2022. 101-101
重松正樹, 佐々木穂高, 東俊文, 矢島安朝, 関根秀志, 大野建州. 歯肉を介したチタンによる免疫応答. 歯科学報. 2021. 121. 2. 192-192
中村ゆり子, 小野寺晶子, 秀島樹, 森田奈那, 渡邊豪士, 加藤宏, 國分克寿, 橋本和彦, 佐々木文, 松坂賢一, et al. Gorlin症候群診断遺伝子パネル開発とその信頼性の検証. 日本口腔診断学会雑誌. 2021. 34. 1. 67-67
小倉弘之, 中村貴, 石井武展, 齋藤暁子, 小野寺晶子, 山口朗, 末石研二, 西井康, 東俊文. 東京歯科大学における新たな研究の展開 Apert症候群における頭蓋縫合早期癒合メカニズムの解明. 歯科学報. 2021. 120. 4. 486-486

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Education (2)：

Professional career (1)：

Keio University, Department of Medicine (Keio University Department of Medicine)

Work history (12)：

2019/06 - 現在 Tokyo Dental College Oral Health Science Center
2009/08 - 現在 Tokyo Dental College Department of Biochemistry Professor
2009/04 - 2009/07 Tokyo Dental College Oral Health Science Center Molecular Regeneration Unit
2008/01 - 2009/03 Tokyo Dental College Oral Health Science Center Molecular Regeneration Unit
2006/11 - 2008/01 Tokyo Dental College Oral Health Science Center Molecular Regeneration Unit

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Awards (4)：

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