Sudo Hitomi

スドウヒトミ | Sudo Hitomi

Affiliation and department：
Job title：主任研究員(任常)
Research theme for competitive and other funds (6)：

2021 - 2024 悪性中皮腫根治に向けて-ポドプラニン標的α線放射免疫療法と高精度線量評価法の開発
2018 - 2021 Radioimmunotherapy with Anti-podoplanin cancer-specific monoclonal antibody
2015 - 2018 Investigation of the molecular mechanism of transiently elevated tumor uptake of PET tracers at early time points after X-ray radiation
2015 - 2018 Development of radiation exposed-cell tracking system for imaging within living cells
2012 - 2015 Development of new tumor PET probes: C-11-labeled aminoisobutyric acid and analogs

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Papers (48)：

Honoka Obata, Atsushi B Tsuji, Hitomi Sudo, Aya Sugyo, Kaori Hashiya, Hayato Ikeda, Masatoshi Itoh, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, et al. Novel Auger-Electron-Emitting 191Pt-Labeled Pyrrole-Imidazole Polyamide Targeting MYCN Increases Cytotoxicity and Cytosolic dsDNA Granules in MYCN-Amplified Neuroblastoma. Pharmaceuticals (Basel, Switzerland). 2023. 16. 11
Honoka Obata, Atsushi B Tsuji, Hitomi Sudo, Aya Sugyo, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang. Precise quantitative evaluation of pharmacokinetics of cisplatin using a radio-platinum tracer in tumor-bearing mice. Nuclear medicine communications. 2022. 43. 11. 1121-1127
Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Yoshinori Narita, Kenji Taniguchi, Takayuki Nemoto, Fumihisa Isomura, Norihiro Awaya, Mika Kamata-Sakurai, Tatsuya Higashi. In vivo validation of the switch antibody concept: SPECT/CT imaging of the anti-CD137 switch antibody Sta-MB shows high uptake in tumors but low uptake in normal organs in human CD137 knock-in mice. Translational Oncology. 2022
Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Yosuke Harada, Satoshi Nagayama, Toyomasa Katagiri, Yusuke Nakamura, Tatsuya Higashi. FZD10-targeted α-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model. Cancer Science. 2022
Yoichi Takakusagi, Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Masahiro Yasunaga, Yasuhiro Matsumura, Fumio Sugawara, Kengo Sakaguchi, Tatsuya Higashi. The natural sulfoglycolipid derivative SQAP improves the therapeutic efficacy of tissue factor-targeted radioimmunotherapy in the stroma-rich pancreatic cancer model BxPC-3. Translational oncology. 2022. 15. 1. 101285-101285

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MISC (6)：

須藤仁美, 辻厚至, 須堯綾, 小泉満, 黒澤仁, 黒澤良和, 佐賀恒夫, 東達也. 免疫抑制に関与するCD73の発現の非侵襲的イメージング(Development of a noninvasive imaging technique to detect the expression of CD73 mediating immunosuppression in cancer). 日本癌学会総会記事. 2018. 77回. 804-804
Ryuichi Nishii, Tsuneo Saga, Hitomi Sudo, Takashi Togawa, Keiichiro Yoshinaga, Tatsuya Higashi. Assessment of 4DST uptake and Ki-67 index in patients with lung tumor in comparison with FDG uptake. JOURNAL OF NUCLEAR MEDICINE. 2017. 58
Chie Suzuki, Atsushi B. Tsuji, Koichi Kato, Hitomi Sudo, Ming-Rong Zhang, Yasushi Arano, Tsuneo Saga. Synthesis and biological evaluation of 2-amino-2-[C-11]methyl-butanoic acid as a potential PET probe for tumor imaging. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2015. 58. S305-S305
須堯綾, 辻厚至, 須藤仁美, 鵜飼由範, 黒澤仁, 黒澤良和, 佐賀恒夫. 90Y標識抗トランスフェリン受容体抗体の膵癌モデルマウスにおける治療効果の評価. 核医学. 2013. 50. 3. S216-S216
Atsushi B. Tsuji, Koichi Kato, Aya Sugyo, Hitomi Sudo, Chisato Yoshida, Ming-Rong Zhang, Saga Tsuneo. Assessment of C-11-2-Aminoisobutyric Acid in Nude Mice with Tumor and Inflammation. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2011. 54. S198-S198

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