Ishizaki Takahiro

Affiliation and department：
Job title： Lecturer

Research field (2)： Molecular biology , Parasitology

Research keywords (6)： Erythrocyte Invasion Mechanism , Gene Editing , Molecular Parasitology , haemoprotozoan , Babesia , Plasmodium

Research theme for competitive and other funds (8)：

2024 - 会議開催費助成(第15回蠕虫研究会)
2023 - 2024 ウシバベシア原虫赤内期必須遺伝子の同定に向けた次世代型CRISPRスクリーニング基盤の構築
2021 - 2023 Elucidation of the sensing mechanism in malaria parasite that play a role in host environment adaptation
2021 - 2023 分裂体期脂質転換酵素による新規『遅延死』モデルの構築
2020 - 2022 Elucidation of the DGK regulated erythrocyte invasion mechanism of malaria parasites

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Papers (15)：

Sophia Hernandez, Ravish Rashpa, Thorey K. Jonsdottir, Martina S. Paoletta, Maria Rayón Diaz, Severine Chevalley-Maurel, Takahiro Ishizaki, Chris J. Janse, Blandine Franke-Fayard, Mathieu Broche, et al. Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of the Plasmodium berghei infected red blood cell. bioRxiv. 2024
Thorey K Jonsdottir, Martina S Paoletta, Takahiro Ishizaki, Sophia Hernandez, Maria Ivanova, Alicia Herrera Curbelo, Paulina A Saiki, Martin Selinger, Debojyoti Das, Johan Henriksson, et al. A scalable CRISPR-Cas9 gene editing system facilitates CRISPR screens in the malaria parasite Plasmodium berghei. bioRxiv. 2024
T. Ishizaki, S. Hernandez, M.S. Paoletta, T. Sanderson, E.S.C. Bushell. CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact. Biochemical Society Transactions. 2022
Hassan Hakimi, Masahito Asada, Takahiro Ishizaki, Shinichiro Kawazu. Isolation of viable Babesia bovis merozoites to study parasite invasion. Scientific Reports. 2021. 11. 1. 16959-16959
Nattawat Chaiyawong, Takahiro Ishizaki, Hassan Hakimi, Masahito Asada, Kazuhide Yahata, Osamu Kaneko. Distinct effects on the secretion of MTRAP and AMA1 in Plasmodium yoelii following deletion of acylated pleckstrin homology domain-containing protein. Parasitology International. 2021. 102479-102479

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MISC (2)：

Books (1)：

Lectures and oral presentations (33)：

北海道のエゾシカ(Cervus nippon yezoensis)におけるB. divergensの感染状況の把握と進化系統解析
(第167回獣医学会学術集会 2024)
Involvement of a pseudokinase pPK4 in the exflagellation center formation in Plasmodium yoelii
(21st International Congress for Tropical Medicine and Malaria 2024)
Essential role of pleckstrin homology domain-containing protein 1 (PH1) in AMA1 secretion during erythrocyte invasion by Plasmodium yoelii
(21st International Congress for Tropical Medicine and Malaria 2024)
Phosphatidic acid, converted by Plasmodium yoelii diacylglycerol kinase 1 (PyDGK1), plays a pivotal role in protein secretion and distribution on merozoite surface during erythrocyte invasion
(The 22nd Awaji International Forum on Infection and Immunity 2024)
Plasmodium yoelii cAMP-dependent protein kinase regulates parasite development in the mosquito vector and is essential for infection of the vertebrate host
(The 22nd Awaji International Forum on Infection and Immunity 2024)

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Education (2)：

2016 - 2020 Nagasaki University Graduate School of Biomedical Sciences
2010 - 2016 Obihiro University of Agriculture and Veterinary Medicine Faculty of Animal Husbandry

Professional career (2)：

Work history (9)：

2023/12 - 現在 College of Veterinary Medicine, Rakuno Gakuen University Unit of Medical Zoology Lecturer
2021/04 - 現在 National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine Collaborative researchers
2021/04 - 2023/11 Institute of Tropical Medicine (NEKKEN), Nagasaki University Department of Protozoology Visiting fellow
2021/05 - 2023/10 Molecular Infection Medicine Sweden (MiMS), Umeå University Department of Molecular Biology Postdoctoral stipend
2021/05 - 2023/10 Japan Society for the Promotion of Science Overseas Research Fellow

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Awards (4)：

2023/03 - 日本寄生虫学会第32回奨励賞マラリア原虫の偽キナーゼpPK1に関する研究
2022/03 - The Marine Biological Laboratory Scholarship award for the program Biology of Parasitism
2021/02 - Alumni Association of Institute of Tropical Medicine Incentive award A novel Plasmodium yoelii pseudokinase, PypPK1, is involved in erythrocyte invasion and exflagellation center formation.
2018/04 - Wellcome Genome Campus Advanced Courses and Scientific Conferences WGC Advanced Courses Travel award

Association Membership(s) (3)：

日本獣医寄生虫学会 , 日本獣医学会 , 日本寄生虫学会

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