Rchr
J-GLOBAL ID:202001008186417744   Update date: May. 05, 2024

Wang Dengli

ワン デンリ | Wang Dengli
Affiliation and department:
Homepage URL  (1): http://soran.cc.okayama-u.ac.jp/view?l=ja&u=895c29db9c0b48ea74506e4da22f6611
Research field  (2): Pharmacology ,  Pharmacology
Research keywords  (3): anti-HMGB1 antibody ,  Inflammation ,  Intracerebral Hemorrhage
Research theme for competitive and other funds  (8):
  • 2022 - 2025 Validation and drug development for anti-cancer therapy targeting hemolysis-hemopexin related axis
  • 2021 - 2024 HMGB1-HRGバランスに着目した川崎病新規治療薬の開発
  • 2021 - 2024 Verification of preventative effects of monoclonal HMGB1 antibody for spinal cord injury after aortic operation
  • 2020 - 2024 Application of anti-HMGB1 m Ab in intracerebral hemorrhage-induced brain injury in common marmoset and elucidation of HMGB1 translocation mechanism
  • 2020 - 2023 敗血症関連DAMPs拮抗因子HRGの血管保護作用機序の解明
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Papers (34):
  • Simeng Ma, Yoki Nakamura, Takahiro Kochi, Suzuna Uemoto, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Norimitsu Morioka. Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 221-226
  • Handong Qiao, Yuta Morioka, Dengli Wang, Keyue Liu, Shangze Gao, Hidenori Wake, Daiki Ousaka, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori. Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice. European Journal of Pharmacology. 2023. 950. 175702-175702
  • 伊達 慶一, 諏澤 憲, 吉川 真生, 大亀 正義, 土生 智大, 岩田 一馬, 松田 直樹, Yin Min Thu, 枝園 和彦, 山本 寛斉, et al. 非小細胞肺癌の微小環境におけるHigh Mobility Group Box-1 protein(HMGB1)の役割. 日本外科学会定期学術集会抄録集. 2023. 123回. SF-6
  • Shangze Gao, Keyue Liu, Wenhan Ku, Dengli Wang, Hidenori Wake, Handong Qiao, Kiyoshi Teshigawara, Masahiro Nishibori. Histamine induced high mobility group box-1 release from vascular endothelial cells through H-1 receptor. FRONTIERS IN IMMUNOLOGY. 2022. 13
  • Dengli Wang, Daiki Ousaka, Handong Qiao, Ziyi Wang, Kun Zhao, Shangze Gao, Keyue Liu, Kiyoshi Teshigawara, Kenzo Takada, Masahiro Nishibori. Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb. CELLS. 2022. 11. 19
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MISC (12):
  • 圓尾賢悟, 池田裕哉, 坪田真帆, 王登莉, 西堀正洋, 南達郎, 伊藤彰敏, 川畑篤史. 活性化プロテインCは神経障害性疼痛を抑制する:Proteinase-activated receptor-1(PAR1)の関与について. 生体機能と創薬シンポジウム要旨集. 2022. 2022
  • 岸本彩野, 堂本莉紗, 松永浩明, 松本亜紗菜, 坪田真帆, 関口富美子, 王登莉, 西堀正洋, 川畑篤史. Oxaliplatin誘起末梢神経障害には血小板由来HMGB1が関与する. 日本薬理学雑誌. 2022. 157. Supplement
  • 川畑篤史, 岸本彩野, 堂本莉紗, 松永浩明, 松本亜紗菜, 坪田真帆, 関口富美子, WANG Dengli, 西堀正洋. Anti-platelet agents prevent oxaliplation-induced peripheral neuropathy (OIPN): involvement of platelet-derived HMGB1 in OIPN. Pain Research. 2022. 37. 4
  • 青木葉優衣, 谷津健太, 池田裕哉, 関口富美子, 坪田真帆, WANG Dengli, 西堀正洋, 川畑篤史. Distinct mechanisms for release of HMGB1 from macrophages involved in the peripheral neuropathy induced by chemotherapeutic agents, bortezomib and vincristine. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 佐々木花菜, SHIN Eunkyung, 野中結, 坪田真帆, WANG Dengli, 西堀正洋, 川畑篤史. Role of HMGB1 derived from macrophages and enteric glial cells in the butyrate-induced colonic hypersensitivity. 日本薬学会年会要旨集(Web). 2022. 142nd
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Lectures and oral presentations  (11):
  • The therapeutic effects of humanized anti-HMGB1 mAb on intracerebral hemorrhage-induced brain injury in marmoset
    (2021)
  • Treatment of intracerebral hemorrhage with humanized a-HMGB1 mAb in non-human primate brain
    (2021)
  • The therapeutic effects of anti-HMGB1 mAb on subdural hematoma-induced brain injury in rats
    (2020)
  • HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes
    (2020)
  • Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats
    (2020)
more...
Education (3):
  • 2014 - 2017 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
  • 2010 - 2013 Jilin University
  • 2006 - 2010 Changchun University of Chinese Medicine
Professional career (1):
  • PhD. (Okayama University)
Work history (2):
  • 2021/04 - 現在 Okayama University Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry & Pharmaceutical Sciences Assistant Professor
  • 2017/10 - 2021/03 Okayama University Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry & Pharmaceutical Sciences Assistant Professor
Awards (2):
  • 2016/06 - 第37回日本炎症・再生医学会 優秀演題賞
  • 2015/03 - 公益信託岡山ロータリークラブ国際交流振興基金 国際交流奨励賞
Association Membership(s) (4):
Japanese Cancer Association ,  日本神経科学学会 ,  北米神経科学学会 ,  日本薬理学会
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