Wang Dengli

ワンデンリ | Wang Dengli

Affiliation and department：
Homepage URL (1)： http://soran.cc.okayama-u.ac.jp/view?l=ja&u=895c29db9c0b48ea74506e4da22f6611

Research field (2)： Pharmacology , Pharmacology

Research keywords (3)： anti-HMGB1 antibody , Inflammation , Intracerebral Hemorrhage

Research theme for competitive and other funds (10)：

2024 - 2027 Development of a novel therapeutic drug targeting ribonucleoprotein for glioblastoma model
2022 - 2025 Validation and drug development for anti-cancer therapy targeting hemolysis-hemopexin related axis
2021 - 2024 HMGB1-HRGバランスに着目した川崎病新規治療薬の開発
2021 - 2024 Verification of preventative effects of monoclonal HMGB1 antibody for spinal cord injury after aortic operation
2020 - 2024 Application of anti-HMGB1 m Ab in intracerebral hemorrhage-induced brain injury in common marmoset and elucidation of HMGB1 translocation mechanism

Show all

Papers (36)：

Kazue Hisaoka-Nakashima, Yuka Takeuchi, Yukino Saito, Takahisa Shimoda, Yoki Nakamura, Dengli Wang, Keyue Liu, Masahiro Nishibori, Norimitsu Morioka. Glucocorticoids induce HMGB1 release in primary cultured rat cortical microglia. Neuroscience. 2024. 560. 56-66
Shangze Gao, Dengli Wang, Keyue Liu, Yasuko Tomono, Li Fu, Yuan Gao, Yohei Takahashi, Mariko Yata, Masahiro Nishibori. Anti-HMGB1 mAb Therapy Reduces Epidural Hematoma Injury. International journal of molecular sciences. 2024. 25. 11
Simeng Ma, Yoki Nakamura, Takahiro Kochi, Suzuna Uemoto, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Norimitsu Morioka. Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 221-226
Handong Qiao, Yuta Morioka, Dengli Wang, Keyue Liu, Shangze Gao, Hidenori Wake, Daiki Ousaka, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori. Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice. European Journal of Pharmacology. 2023. 950. 175702-175702
伊達慶一, 諏澤憲, 吉川真生, 大亀正義, 土生智大, 岩田一馬, 松田直樹, Yin Min Thu, 枝園和彦, 山本寛斉, et al. 非小細胞肺癌の微小環境におけるHigh Mobility Group Box-1 protein(HMGB1)の役割. 日本外科学会定期学術集会抄録集. 2023. 123回. SF-6

ｍore...

MISC (12)：

圓尾賢悟, 池田裕哉, 坪田真帆, 王登莉, 西堀正洋, 南達郎, 伊藤彰敏, 川畑篤史. 活性化プロテインCは神経障害性疼痛を抑制する:Proteinase-activated receptor-1(PAR1)の関与について. 生体機能と創薬シンポジウム要旨集. 2022. 2022
岸本彩野, 堂本莉紗, 松永浩明, 松本亜紗菜, 坪田真帆, 関口富美子, 王登莉, 西堀正洋, 川畑篤史. Oxaliplatin誘起末梢神経障害には血小板由来HMGB1が関与する. 日本薬理学雑誌. 2022. 157. Supplement
川畑篤史, 岸本彩野, 堂本莉紗, 松永浩明, 松本亜紗菜, 坪田真帆, 関口富美子, WANG Dengli, 西堀正洋. Anti-platelet agents prevent oxaliplation-induced peripheral neuropathy (OIPN): involvement of platelet-derived HMGB1 in OIPN. Pain Research. 2022. 37. 4
青木葉優衣, 谷津健太, 池田裕哉, 関口富美子, 坪田真帆, WANG Dengli, 西堀正洋, 川畑篤史. Distinct mechanisms for release of HMGB1 from macrophages involved in the peripheral neuropathy induced by chemotherapeutic agents, bortezomib and vincristine. 日本薬学会年会要旨集(Web). 2022. 142nd
佐々木花菜, SHIN Eunkyung, 野中結, 坪田真帆, WANG Dengli, 西堀正洋, 川畑篤史. Role of HMGB1 derived from macrophages and enteric glial cells in the butyrate-induced colonic hypersensitivity. 日本薬学会年会要旨集(Web). 2022. 142nd

ｍore...

Lectures and oral presentations (11)：

The therapeutic effects of humanized anti-HMGB1 mAb on intracerebral hemorrhage-induced brain injury in marmoset
(2021)
Treatment of intracerebral hemorrhage with humanized a-HMGB1 mAb in non-human primate brain
(2021)
The therapeutic effects of anti-HMGB1 mAb on subdural hematoma-induced brain injury in rats
(2020)
HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes
(2020)
Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats
(2020)

ｍore...

Education (3)：

2014 - 2017 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
2010 - 2013 Jilin University
2006 - 2010 Changchun University of Chinese Medicine

Professional career (1)：

Work history (2)：

2021/04 - 現在 Okayama University Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry & Pharmaceutical Sciences Assistant Professor
2017/10 - 2021/03 Okayama University Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry & Pharmaceutical Sciences Assistant Professor

Awards (2)：

Association Membership(s) (4)：

Japanese Cancer Association , 日本神経科学学会 , 北米神経科学学会 , 日本薬理学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page