Shimizu Kentaro

シミズケンタロウ | Shimizu Kentaro

Research keywords (7)： ICU , emergency medicine , indirect calorimetry , nutrition , fecal microbiological transplantation , probiotics , microbiota

Research theme for competitive and other funds (26)：

2022 - 2025 重症病態の腸内細菌を介した新規腸管バリア・免疫能の解析と腸内細菌叢再構築法の確立
2022 - 2025 網羅的生体分子情報に基づく重症熱傷病態の中心的分子解明と新規治療薬開発
2022 - 2025 脂肪細胞による全身性炎症反応制御:オートファジーとアディポカイン産生
2022 - 2025 網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築
2021 - 2024 シングル細胞シークエンスを用いた敗血症における免疫抑制病態の解明と新規治療法開発

2020 - 2023 The association between gut microbiome and host immunity focused on regulatory T cell in patients with critical illness

2020 - 2023 敗血症の炎症最適化のためのマーカーと分子病態分類の解明:HIVEP1の臨床応用

2019 - 2022 侵襲時再生治療に関する新たな発展:新規炎症増幅メカニズムの制御

2019 - 2022 重症病態での腸内細菌叢を介した免疫システム解明と腸内細菌叢再構築のための治療戦略

2019 - 2022 重症熱傷におけるグリコカリックスからみた血管内皮障害メカニズム解明と制御法の確立

2017 - 2020 Randomized controlled trial of the effect of low carbohydrate and high fat diet on blood glucose variation in critically ill patients

2016 - 2020 A novel approach for diagnosis of meningitis and encephalitis using metagenomic sequencing

2016 - 2019 A novel development of regenerative therapy following acute systemic inflammatory response syndrome: the effects of transplantation of bone marrow-derived mononuclear cells and new rejuvenation factor

2016 - 2019 Citrullinated histon H3 for control of ciritical illness

2016 - 2019 Elucidation of mechanisms between endothelial injury and host immune response in severe trauma patients

2016 - 2019 Explanatory research of consciousness related substances in iPS cell-derived brain microvascular endothelial cell models

2015 - 2018 elucidation of the brain circulation during prehospital resuscitation

2015 - 2018 Establishment of methods for immune response analysis of lymphocytes and neutrophils against sepsis and trauma

2015 - 2018 A novel strategy for organ dysfunctions following systemic inflammatory response syndrome: the effect of new rejuvenation factor GDF11

2012 - 2015 Establishment of synbiotic therapy in severe sepsis

2010 - 2013 侵襲期低栄養患者に関するリスク評価及び病態解析

2010 - 大学病院における医療安全・質向上方策の定量的評価に関する研究

2006 - 2008 A Study on the Systematic Approach to Emergency Management Medicine : From Inpatient Collapse to Local Cooperation tor Disaster and Terrorism

2008 - 2010 Development and measurement of quality indicators to evaluated patient safety and quality improvement in a Japanese university hospital

2005 - 2007 Gut flora and synbiotics therapy in patients with severe SIRS

2005 - 2007 腹部内臓血行動態と蘇生後臓器機能障害との関連からみた新しい心肺蘇生法の開発

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Papers (85)：

Keigo Kihara, Yuta Kajiyama, Yasuyoshi Kimura, Shuhei Okazaki, Naoya Esa, Ryosuke Nobe, Kentaro Shimizu, Kiyoshi Ohno, Daisuke Motooka, Takuhiro Matsumura, et al. Adult-onset botulism in a Japanese woman with prolonged spore excretion. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2023
清水健太郎, 北村哲久, 前田達也, 小倉裕司, 嶋津岳士. DNAR(do not attempt resuscitation)は高齢者心停止症例の救急医療機関選定に影響する大阪市救急搬送記録を用いた地域網羅的解析. 日本臨床救急医学会雑誌. 2023. 26. 4. 473-479
Takeshi Ebihara, Kentaro Shimizu, Yumi Mitsuyama, Hiroshi Ogura, Jun Oda. Association between high cardiac output at altitude and acute mountain sickness: preliminary study on Mt. Fuji. Journal of physiological anthropology. 2023. 42. 1. 6-6
Kentaro Shimizu, Haruhiko Hirata, Daijiro Kabata, Natsuko Tokuhira, Moe Koide, Akiko Ueda, Jotaro Tachino, Ayumi Shintani, Akinori Uchiyama, Yuji Fujino, et al. Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022. 28. 4. 548-553
Arisa Muratsu, Mitsunori Ikeda, Kentaro Shimizu, Shoichiro Kameoka, Daisuke Motooka, Shota Nakamura, Hisatake Matsumoto, Hiroshi Ogura, Takeshi Shimazu. Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model. ACUTE MEDICINE & SURGERY. 2022. 9. 1

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MISC (321)：

清水健太郎. マイクロバイオーム研究の最前線マイクロバイオームと救急領域病態. 日本化学療法学会雑誌. 2021. 69. 2. 156-156
中川雄公, 清水健太郎, 島崎淳也, 舘野丈太郎, 廣瀬智也, 嶋津岳士. 救急科専門医を核とした医療チームによる急性肝不全診療体制の有効性. 日本救急医学会雑誌. 2021. 32. 2. 64-72
大西伸也, 大須賀章倫, 松浦裕司, 蛯原健, 松本寿健, 清水健太郎, 小倉裕司. Resistin, among adipokines, forms a network with other cytokines and is associated with prognosis in major burns. 日本熱傷学会総会・学術集会プログラム・抄録集. 2021. 47th
大須賀章倫, 大須賀章倫, 石原拓磨, 石原拓磨, 清水健太郎, 新谷歩, 小倉裕司, 上山昌史. Natural Kinetics of Blood Cells Following Major Burn Injury: Impact of Early Decreases in White Blood Cells and Platelets as Prognostic Markers of Mortality. 熱傷(Web). 2021. 47. 2
清水健太郎, 小倉裕司, 嶋津岳士. 臓器障害と臓器連関-その機序と治療- 重症患者における腸内細菌叢の変化と感染合併症の臓器連関粘膜免役を介したつながり. 日本救急医学会雑誌. 2020. 31. 11. 730-730

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Patents (2)：

Work history (3)：

2014/12/01 - 現在 Osaka University Osaka University Hospital Assistant Professor
2014/07/01 - 2014/11/30 Osaka University Osaka University Hospital Assistant Professor
2009/04/01 - 2012/03/31 Osaka University Osaka University Hospital Assistant Professor

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