Itonaga Hidehiro

イトナガヒデヒロ | Itonaga Hidehiro

Affiliation and department：
Job title： Senior Research Associate

Research field (4)： Tumor biology , Tumor diagnostics and therapeutics , Hematology and oncology , Molecular biology

Research keywords (11)： Epigenetic alterations , Genetic alterations , Molecular target , Chemotherapy , Allogeneic hematopoietic stem cell transplantation , Adult T-cell leukemia-lymphoma , Acute leukemia , Myeloproliferative neoplasms , Chronic myeloid leukemia , Myelodysplastic syndrome , Acute myeloid leukemia

Research theme for competitive and other funds (15)：

2024 - 2025 2024年度長崎県医師会医学研究助成金
2022 - 2025 「FLT3遺伝子変異を有する再発又は難治性の急性骨髄性白血病患者において、ギルテリチニブが同種造血幹細胞移植後成績に及ぼす影響」研究のためのヒストリカルデータ取得研究
2022 - 2025 FLT3遺伝子変異を有する再発又は難治性の急性骨髄性白血病患者における、ギルテリチニブが同種造血幹細胞移植後成績に及ぼす影響に関する観察研究
2023 - 2025 無人航空機を用いた血液製剤搬送の実行可能性と品質への影響に関する研究
2022 - 2025 Novel agents targeting DNA repair pathway regulated by protein arginine methyltransferases in myeloid neoplasms

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Papers (108)：

Hidehiro Itonaga, Takuya Fukushima, Koji Kato, Nobuaki Nakano, Takeharu Kato, Takashi Tanaka, Tetsuya Eto, Yasuo Mori, Toshiro Kawakita, Naoyuki Uchida, et al. Allogeneic transplantation for adult T-cell leukemia/lymphoma in adolescent and young adults and young patients: A nationwide retrospective study by the ATL working group of the Japan society for transplantation and cellular therapy. Hematological oncology. 2024. 42. 6. e3315
Makoto Yoshimitsu, Takashi Tanaka, Nobuaki Nakano, Koji Kato, Hiroyuki Muranushi, Masahito Tokunaga, Ayumu Ito, Jun Ishikawa, Tetsuya Eto, Satoko Morishima, et al. Comparative outcomes of various transplantation platforms, highlighting haploidentical transplants with post-transplantation cyclophosphamide for adult T-cell leukaemia/lymphoma. British journal of haematology. 2024
Atsushi Marumo, Yasunobu Nagata, Machiko Fujioka, Shuhei Kurosawa, Yuho Najima, Emiko Sakaida, Noriko Doki, Kentaro Fukushima, Shuichi Ota, Katsuhiro Shono, et al. Outcome of donor lymphocyte infusion after allogeneic hematopoietic stem cell transplantation in relapsed myelodysplastic syndrome. Cytotherapy. 2024
Miki Hashimoto, Takeharu Kato, Kenichi Yokota, Hikaru Sakamoto, Makiko Horai, Masataka Taguchi, Hidehiro Itonaga, Shinya Sato, Maki Baba, Koji Ando, et al. Improved survival among elderly patients with aggressive adult T-cell leukemia/lymphoma: Impact of mogamulizumab-containing chemotherapy. International journal of hematology. 2024
Machiko Fujioka, Hidehiro Itonaga, Hideyuki Nakazawa, Tetsuya Nishida, Keisuke Kataoka, Takashi Ikeda, Shinichi Kako, Ken-Ichi Matsuoka, Koji Adachi, Shini-Chiro Fujiwara, et al. Superior survival after unrelated allogeneic stem cell transplantation with low-dose ATG compared to low-dose TBI in myeloablative fludarabine/busulfan-based regimen for MDS on behalf of the adult MDS Working Group of the JSTCT. Transplantation and cellular therapy. 2024

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MISC (68)：

糸永英弘. 慢性骨髄単球性白血病. 別冊日本臨牀血液症候群(第3版). 2024
糸永英弘. クローン性造血と骨髄系腫瘍. 血液内科. 2023. 86. 1. 42-47
糸永英弘, 木田理子, 土岐典子, 内田直之, 小澤幸泰, 福田隆浩, 上田恭典, 片山雄太, 諫田淳也, 一戸辰夫, et al. Outcomes of allo-HSCT for therapy-related MDS compared to de novo MDS by propensity-score matching. 日本造血・免疫細胞療法学会総会プログラム・抄録集. 2022. 44th
糸永英弘. 慢性骨髄単球性白血病の病態と治療. 血液内科. 2021. 83. 5. 648-654
Shuhei Kurosawa, Yoshimitsu Shimomura, Hidehiro Itonaga, Yuho Najima, Takeshi Kobayashi, Yukiyasu Ozawa, Yoshinobu Kanda, Shinichi Kako, Toshiro Kawakita, Ken-Ichi Matsuoka, et al. Comparison of Myeloablative Versus Reduced-Intensity Fludarabine/Busulfan Regimen in Patients with Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. BLOOD. 2021. 138. 3692-+

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Books (15)：

最新の臨床WEB
南江堂 2024
別冊日本臨牀血液症候群(第3版)
日本臨牀社 2024
血液内科
科学評論社 2023
血液内科
2021
悪性リンパ腫に対する新たな治療展開
クリニコ出版 2020 ISBN:9784910396040

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Lectures and oral presentations (157)：

成人T細胞白血病リンパ腫に対する同種造血細胞移植における女性ドナー/男性レシピエントの影響
(第86回日本血液学会学術集会 2024)
成人T細胞白血病・リンパ腫に対するPTCYを用いたHLA半合致移植成績
(第86回日本血液学会学術集会 2024)
Progress in outcomes of allogeneic transplantation for atypical CML over two decades
(2024)
同種造血幹細胞移植が奏功した全身性炎症を伴う低リスクMDS
(第86回日本血液学会学術集会 2024)
Allogeneic transplantation as a therapeutic option for atypical chronic myeloid leukemia
(2024)

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Education (2)：

- 2013 Nagasaki University Graduate School of Biomedical Sciences Medical Science in Life Sciences and Radiation Research
1999 - 2005 Nagasaki University School of Medicine

Work history (14)：

2023/04 - 現在 Nagasaki University Hospital Transfusion and Cell Therapy Unit
2023/04 - 現在長崎大学病院移植医療センター組織移植部門
2022/04 - 2023/03 長崎大学病院移植医療センター造血幹細胞移植部門
2021/08 - 2023/03 Nagasaki University Hospital Department of Hematology Research associate
2018/12 - 2021/07 Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami Department of Biochemistry and Molecular Biology Post-doctoral

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Committee career (8)：

2024/06 - 現在日本輸血・細胞治療学会評議員
2024/03 - 現在日本輸血・細胞治療学会九州支部会評議員
2023/04 - 現在日本造血・免疫細胞療法学会骨髄異形成症候群(成人)-WG 責任者
2023/01 - 現在アグレッシブ成人T細胞白血病・リンパ腫コンソーシアム運営委員
2022/04 - 現在 Japanese Society for Transplantation and Cellular Therapy Councilor

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Awards (5)：

2024/03 - 長崎県医師会長崎県医師会医学研究助成金
2022/09 - 公益財団法人武田科学振興財団医学系研究助成 (がん領域 (臨床))
2020/03 - The Japan Society for Hematopoietic Cell Transplantation JSHCT Working Group Research Award Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and related disorders
2017/06 - Nagasaki University School of Medicine The Tsunoo Award for Scientific Excellence The relationship of genomic and epigenomic alterations with clinical response in myeloid neoplasms
2014/05 - Japanese Society of Hematology Best poster awards of the 5th Japanese Society of Hematology International Symposium Expression of myeloperoxidase in acute myeloid leukemia blasts mirrors the distinct DNA methylation pattern involving the downregulation of DNA methyltransferase DNMT3B

Association Membership(s) (7)：

日本組織移植学会 , America Society of Hematology , The Japan Society of Transfusion Medicine and Cell Therapy , Japanese Society of Medical Oncology , The Japanese Society for Transplantation and Cellular Therapy , The Japanese Society of Internal Medicine , Japanese Society of Hematology

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