Hosokawa Hiroyuki

ホソカワヒロユキ | Hosokawa Hiroyuki

Research theme for competitive and other funds (7)：

2019 - 2024 Stage-specific roles of Notch signaling on induction of T cell development from hematopoietic progenitor cells
2014 - 2019 Elucidation of pathogenic immune memory formation and maintenance
2014 - 2015 活性型/抑制型GATA3複合体の形成と制御メカニズムの解明
2011 - 2012 Functions of posttranscriptional regulation of GATA3 in Th2 cells
2008 - 2009 Identification of the functional molecular complexes of GATA3 in Th2 cells.

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Papers (66)：

Sawako Suzuki, Divya Venkatesh, Hiroaki Kanda, Akitoshi Nakayama, Hiroyuki Hosokawa, Eunyoung Lee, Takashi Miki, Brent R. Stockwell, Koutaro Yokote, Tomoaki Tanaka, et al. Data from GLS2 Is a Tumor Suppressor and a Regulator of Ferroptosis in Hepatocellular Carcinoma. Cancer Research. 2023
Maria Koizumi, Yuichi Kama, Ken-ichi Hirano, Yusuke Endo, Tomoaki Tanaka, Katsuto Hozumi, Hiroyuki Hosokawa. Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells. Journal of Biological Chemistry. 2022. 298. 11. 102506-102506
Masanori Fujimoto, Masataka Yokoyama, Masahiro Kiuchi, Hiroyuki Hosokawa, Akitoshi Nakayama, Naoko Hashimoto, Ikki Sakuma, Hidekazu Nagano, Kazuyuki Yamagata, Fujimi Kudo, et al. Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis. Nature Communications. 2022. 13. 1. 5408-5408
Ken-ichi Hirano, Hiroyuki Hosokawa, Takashi Yahata, Kiyoshi Ando, Masayuki Tanaka, Jin Imai, Masaki Yazawa, Masato Ohtsuka, Naoko Negishi, Sonoko Habu, et al. Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium. Frontiers in Immunology. 2022. 13. 852427-852427
Ken-ichi Hirano, Hiroyuki Hosokawa, Maria Koizumi, Yusuke Endo, Takashi Yahata, Kiyoshi Ando, Katsuto Hozumi. LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. eLife. 2021. 10

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MISC (20)：

細川裕之. Cell type-specific actions of Bcl11b in pro-T and group 2 innate lymphoid cells. 月刊臨床免疫・アレルギー科. 2020. 74. 1
細川裕之, 細川裕之. 最新リンパ球研究情報転写因子Bcl11bによるT細胞分化制御機構. 月刊臨床免疫・アレルギー科. 2019. 72. 5
細川裕之, 細川裕之. T細胞の初期発生において転写因子PU.1はコファクターを再配置することにより遺伝子発現を制御する. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
細川裕之, 中山俊憲. 【アレルギーとインターロイキン最近の進歩】 IL-4,GATA3とアレルギー. アレルギー・免疫. 2016. 23. 11. 1472-1477
細川裕之, ROTHENBERG Ellen V. Bcl11bによるT細胞運命決定の分子メカニズムの解明. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th

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