Yazawa Ikuru

ヤザワイクル | Yazawa Ikuru

Affiliation and department：
Job title：教授

Research field (1)： Neurology

Research keywords (6)：神経変性疾患 , 神経内科学 , rehabilitation , 疾患モデル , multiple system atrophy , polyglutamine disease

Research theme for competitive and other funds (6)：

2023 - 2026 神経変性疾患におけるリハビリテーション治療効果の機序の解明
2017 - 2022 Therapeutic targets for multiple system atrophy
2013 - 2016 微小管蛋白に結合するα-synuclein蓄積抑制法の開発
2010 - 2012 Inhibiting neuronal alpha-synuclein accumulation caused by oli godendrocytic inclusions
2001 - 2001 歯状核赤核淡蒼球ルイ体萎縮症における異常な蓄積蛋白のプロテオミクス

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Papers (22)：

Michiaki Kinoshita, Kiyomitsu Oyanagi, Akira Matsushima, Yasufumi Kondo, Shigeki Hirano, Keisuke Ishizawa, Kenji Ishihara, Seishi Terada, Teruhiko Inoue, Ikuru Yazawa, et al. Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): Estimation of pathological lesion stage from brain images. Journal of the Neurological Sciences. 2024. 461. 123027-123027
Iwase T, Yoshida M, Iwasaki Y, Suzuki S, Yabuta H, Koizumi R, Moriyoshi H, Yazawa I. Selective extension of cerebral vascular calcification in an case of Fahr’s syndrome;associated with asymptomatic hypoparathyroidism. Neuropathology. 2021. 41. 5. 387-395
Ikuru Yazawa. Animal models for MSA. Clinical Neuroscience. 2019. 37. 9. 1073-1076
Iwase T, Yoshida M, Hashizume Y, Yazawa I, Takahashi S, Ando T, Ikeda T, Nokura K. Intracranial vascular calcification with extensive white matter changes in an autopsy case of pseudopseudohypoparathyroidism. Neuropathology. 2018. 39. 39-46
Oyanagi K, Kinoshita M, Suzuki-Kouyana E, Inoue T, Nakahara A, Tokiwai M, Arai N, Satoh JI, Aoki N, Jinnai K, et al. Hereditary diffuse leukoencephalopathy with axonal spheroids and Nasu-Hakola disease: Lesion staging and microglial alteration. Brain Pathology. 2017. 27. 6. 748-769

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MISC (9)：

Hiroshi Ito, Chenghua Jin, Yasuyo Suzuki, Ikuru Yazawa. Oligodendrocytic alpha-synuclein accumulation causes neuronal synaptic dysfunction in a mouse model of multiple system atrophy. NEUROSCIENCE RESEARCH. 2011. 71. E293-E293
Yasuyo Suzuki, Kimiko Nakayama, Ikuru Yazawa. The role of interaction between alpha-synuclein and beta-III tubulin in an MSA mouse model. NEUROSCIENCE RESEARCH. 2011. 71. E190-E190
Kimiko Nakayama, Yasuyo Suzuki, Ikuru Yazawa. The role of beta-III tubulin in alpha-synuclein accumulation of multiple system atrophy (MSA). NEUROSCIENCE RESEARCH. 2010. 68. E194-E194
Yasuyo Suzuki, Ikuru Yazawa. Cytoplasmic aggregation of C-terminal ATN1 fragment in Dentatorubral-pallidoluysian atrophy (DRPLA). NEUROSCIENCE RESEARCH. 2010. 68. E196-E196
Kimiko Nakayama, Yasuyo Suzuki, Ikuru Yazawa. Molecular mechanisms to form insoluble complex in a mouse model of multiple system atrophy (MSA). NEUROSCIENCE RESEARCH. 2009. 65. S245-S245

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Books (10)：

Notes on lifestyle-related diseases 2nd
2024
Japanese textbook of basic neurology, 2nd edition
Ichiryusha 2022 ISBN:9784867431115
Japanese textbook of basic neurology
Ichiryushobo 2020
Notes on Lifestyle-related Diseases
2019
非定型パーキンソニズム : 基礎と臨床
文光堂 2019 ISBN:9784830615474

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Lectures and oral presentations (4)：

Calcification of the cerebellar dentate nucleus in Centenarians
(FENS 2020 Virtual Forum 2020)
alpha-synuclein accumulation in a mouse model of MSA
(Parkinson disease and motor diseases 2018)
シヌクレイノパシーの分子病態をめぐる研究の進歩
(第36回日本認知症学会学術集会シンポジウム 2017)
Effect of microtubule depolymerization on alpha-synuclein accumulation
(4th International congress on multiple system atrophy, France 2012)

Education (1)：

Professional career (1)：

Work history (6)：

2020 - 現在 Tokoha University Faculty of Health and Medical Sciences
2018 - 2019 Nagoya University Research Institute of Environmental Medicine
2003 - 2005 University of Pennsylvania School of Medicine, CNDR visiting scholar
2000 - 2003 身体障害者福祉法医師(東京都)
1990 - 1998 The University of Tokyo Faculty of Medicine University Hospital Department of Neurology

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Committee career (1)：

Awards (4)：

Association Membership(s) (3)：

American Society for Investigative Pathology , 日本内科学会 , Board of Clinical Neurologist certified by Japanese Society of Neurology

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