Rchr
J-GLOBAL ID：202001009255066432
Update date: Mar. 03, 2024
Shindo Naoya
シンドウ ナオヤ | Shindo Naoya
Affiliation and department：
Research theme for competitive and other funds (3)：
- 2022 - 2025 新規可逆的リジン修飾化学の開発とコバレントドラッグ創薬の標的拡張
- 2019 - 2022 Bicyclobutane carboxylic amide as a cysteine-directed strained electrophile for selective targeting of proteins
- 2017 - 2019 Development of highly target selective covalent inhibitors
Papers (22)：
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Izumi Kato, Yudai Ogawa, Fumika Yakushiji, Jiro Ogura, Masaki Kobayashi, Naoya Shindo, Satoshi Ichikawa, Katsumi Maenaka, Masahiro Sakaitani. Beneficial effects of a new neuroprotective compound in neuronal cells and MPTP-administered mouse model of Parkinson's disease. Chemical communications (Cambridge, England). 2023. 59. 82. 12306-12309
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Daiki Yamane, Ryo Tetsukawa, Naoki Zenmyo, Kaori Tabata, Yuya Yoshida, Naoya Matsunaga, Naoya Shindo, Akio Ojida. Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines. Journal of medicinal chemistry. 2023. 66. 13. 9130-9146
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Marie Taniguchi, Sai Yasukochi, Wakaba Yamakawa, Yuya Tsurudome, Akito Tsuruta, Michiko Horiguchi, Kentaro Ushijima, Tomohiro Yamashita, Naoya Shindo, Akio Ojida, et al. Inhibition of tumor-derived CCL2 expression attenuates tactile allodynia in NCTC 2472 fibrosarcoma-inoculated mice. Molecular pharmacology. 2023
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Yuya Hirose, Naoya Shindo, Makiko Mori, Satsuki Onitsuka, Hikaru Isogai, Rui Hamada, Tadanari Hiramoto, Jinta Ochi, Daisuke Takahashi, Tadashi Ueda, et al. Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease. Journal of medicinal chemistry. 2022. 65. 20. 13852-13865
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Daiki Yamane, Satsuki Onitsuka, Suyong Re, Hikaru Isogai, Rui Hamada, Tadanari Hiramoto, Eiji Kawanishi, Kenji Mizuguchi, Naoya Shindo, Akio Ojida. Selective Covalent Targeting of SARS-CoV-2 Main Protease by Enantiopure Chlorofluoroacetamide. 2021
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MISC (9)：
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黒田悠介, 進藤直哉, 竹本佳司, 高須清誠. イナミドを基質をした多置換キノリン合成法の開発. 日本薬学会年会要旨集(CD-ROM). 2013. 133rd
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高須清誠, 黒田悠介, 進藤直哉, 竹本佳司. 触媒的連続反応による多置換キノリンの新規合成法. 日本薬学会年会要旨集. 2011. 131st. 2
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高須清誠, 進藤直哉, 北浦和夫, 竹本佳司. 触媒制御での4π電子環状反応における回転選択性の逆転. 日本薬学会年会要旨集. 2011. 131st. 2
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進藤直哉, 竹本佳司, 高須清誠. 4π電子環状反応による2-アゼチンの開環における触媒制御による回転選択性の逆転. 反応と合成の進歩シンポジウム講演要旨集. 2010. 36th
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進藤直哉, 竹本佳司, 高須清誠. 軸性不斉を有する多置換α,β-不飽和アミジンの合成. 日本薬学会年会要旨集. 2009. 129th. 2
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Education (3)：
- 2008 - 2011 Kyoto University Graduate School of Pharmaceutical Sciences Division of Physical and Organic Chemistry
- 2006 - 2008 Tohoku University Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
- 2002 - 2006 Tohoku University Faculty of Pharmaceutical Sciences
Work history (5)：
- 2023/10 - 現在 Kyushu University
- 2023/04 - 2023/09 Hokkaido University Faculty of Pharmaceutical Sciences
- 2016/11 - 2023/03 Kyushu University
- 2013/06 - 2016/10 Kyushu University
- 2011/05 - 2013/04 The Scripps Research Institute Department of Chemistry Research Associate
Association Membership(s) (4)：
日本ケミカルバイオロジー学会
, 有機合成化学協会
, 日本化学会
, 日本薬学会
