Imai Shunsuke

イマイシュンスケ | Imai Shunsuke

Affiliation and department：
Job title：上級研究員

Research field (2)： Pharmaceuticals - analytical and physicochemistry , Structural biochemistry

Research theme for competitive and other funds (3)：

Papers (26)：

Shun Kaneko, Shunsuke Imai, Tomomi Uchikubo-Kamo, Tamao Hisano, Nobuaki Asao, Mikako Shirouzu, Ichio Shimada. Structural and dynamic insights into the activation of the μ-opioid receptor by an allosteric modulator. Nature Communications. 2024. 15. 3544
Shunsuke Imai, Hiroshi Suzuki, Yoshinori Fujiyoshi, Ichio Shimada. Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nature Communications. 2023. 14. 1. 4977
Michiko Tajiri, Shunsuke Imai, Tsuyoshi Konuma, Keiko Shimamoto, Ichio Shimada, Satoko Akashi. Evaluation of Drug Responses to Human β₂AR Using Native Mass Spectrometry. ACS Omega. 2023. 8. 27. 24544-24551
Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa. Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail. Journal of Biological Chemistry. 2022. 298. 5. 101844-101844
Shun Kaneko, Shunsuke Imai, Nobuaki Asao, Yutaka Kofuku, Takumi Ueda, Ichio Shimada. Activation mechanism of the μ-opioid receptor by an allosteric modulator. Proceedings of the National Academy of Sciences. 2022. 119. 16

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MISC (13)：

上田卓見, 幸福裕, 竹内恒, 今井駿輔, 白石勇太郎, 嶋田一夫. 溶液NMR法によるGPCRの活性と直結する動的構造平衡の解明-Function-Related Conformational Dynamics of GPCRs Revealed by Solution NMR-ミニ特集生理学的環境での生体高分子の挙動の観察可能性の追求. 日本結晶学会誌 = Journal of the Crystallographic Society of Japan. 2022. 64. 4. 279-284
幸福裕, 今井駿輔, 上田卓見, 嶋田一夫. GPCRのNMR・ESR解析. 細胞. 2021. 53. 5
白石勇太郎, 夏目芽依, 幸福裕, 今井駿輔, 中田國夫, 水越利巳, 上田卓見, 岩井秀夫, 嶋田一夫. 健康・医療・創薬に貢献する物理系薬学研究の最前線 Gタンパク質共役型受容体のシグナル伝達制御機構の解明. 日本薬学会年会要旨集. 2019. 139年会. 1. 136-136
白石勇太郎, 夏目芽依, 幸福裕, 今井駿輔, 中田國夫, 水越利巳, 上田卓見, 岩井秀夫, 嶋田一夫. 区分同位体標識を用いたβ2アドレナリン受容体のリン酸化によるシグナル制御機構の解明. 日本生化学会大会プログラム・講演要旨集. 2018. 91回. [1P-376]
夏目芽依, 白石勇太郎, 幸福裕, 今井駿輔, 中田國夫, 水越利巳, 上田卓見, 岩井秀夫, 嶋田一夫. β2アドレナリン受容体のリン酸化によるシグナル制御機構の解明. 日本生化学会大会プログラム・講演要旨集. 2018. 91回. [1P-377]

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Books (2)：

Lectures and oral presentations (14)：

脳心筋炎ウイルスEMCVのゲノムRNAによる翻訳開始機構の解明
(第62回NMR討論会 2023)
Structural equilibrium underlying ligand-dependent activation of beta2-adrenoreceptor
(IPR x RIKEN (BDR) Symposium 2023 2023)
Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor
(2022)
Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor
(The 7th International Symposium on Drug Discovery and Design by NMR 2022)
Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor
(International Conference on Magnetic Resonance in Biological Systems 2022)

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Education (3)：

2007 - 2010 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Biology
2005 - 2007 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Biology
2001 - 2005 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

Work history (9)：

2020/10 - 現在 RIKEN Center for Biosystems Dynamics Research Senioer Scientist
2019/04 - 2020/09 一般社団法人バイオ産業情報化コンソーシアム特別研究職員
2018/05 - 2019/03 The University of Tokyo Graduate School of Pharmaceutical Sciences
2016/05 - 2018/04 一般社団法人バイオ産業情報化コンソーシアム特別研究職員
2012/04 - 2016/04 Harvard Medical School Department of Biological Chemistry and Molecular Pharmacology Postdoctral researcher

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Awards (2)：

2021/08 - ISMAR-APNMR-NMRSJ-SEST 2021 Taiyo Nippon Sanso Poster Award Structural Equilibrium Underlying Ligand-Dependent Activation of β2-Adrenoreceptor
2010/11 - Young resercher poster award Structural basis underlying the dual gate properties of KcsA.

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