Rchr
J-GLOBAL ID：202001009896190036   Update date: Feb. 14, 2024

Matsumoto Ken-ichiro

マツモト ケンイチロウ | Matsumoto Ken-ichiro
Affiliation and department：
National Institutes for Quantum and Radiological Science and Technology Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate

About National Institutes for Quantum and Radiological Science and Technology Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate


Job title： Group Leader
Research field  (2)： Radiology ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (21)： in vivo measurement ,  oxidative stress ,  spin-probing ,  spin-trapping ,  redox sensitive contrast agent ,  redox mapping ,  レドックス ,  pharmaceutical sciences of contrast agents ,  radiation chemistry ,  ionizing radiation ,  carbon-ion beam ,  heavy-ion beam ,  electron spin resonance ,  electron paramagnetic resonance ,  electron spin resonance imaging ,  electron paramagnetic resonance imaging ,  spectral-spatial imaging ,  oxygen mapping ,  Free Radical ,  Reactive Oxygen Species ,  hydrogen peroxide
Research theme for competitive and other funds  (11)：
  • 2022 - 2025 Proposal of "Quantum PET" and sensing of radiotherapy effect by positron lifetime
  • 2021 - 2024 Physical state and reactivity of highly concentrated hydrogen peroxide clusters induced by X-ray or carbon-ion beam in water
  • 2020 - 2023 Effects of longitudinal magnetic field on biological effectiveness of charged-particle therapy
  • 2018 - 2021 Radiosensitization of heavy-ion beam based on modifying early phase redox reaction
  • 2017 - 2020 Antioxidative effect of ascorbate peroxidase derived from Cyanidioschyzon merolae in mammalian cells
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Papers (136)：
  • Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, et al. Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress-Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol?. Biomolecules. 2024. 14. 1. 128-128
  • Yoshihiro Kawabata, Tomoko Fukushige, Hiroko P. Indo, Ken-ichiro Matsumoto, Megumi Ueno, Ikuo Nakanishi, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Sirirat Surinkaew, Jitbanjong Tangpong, et al. Hair Follicle Damage after 100 mGy Low-Dose Fractionated X-Ray Irradiation and the Protective Effects of TEMPOL, a Stable Nitroxide Radical, against Radiation. Radiation Research. 2024
  • Hiromu Ito, Yoshimi Shoji, Megumi Ueno, Ken-ichiro Matsumoto, Ikuo Nakanishi. Photodynamic Therapy for X-ray-Induced Radiation-Resistant Cancer Cells. Pharmaceutics. 2023. 15. 11. 2536-2536
  • Hiromu Ito, Yoshimi Shoji, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Ikuo Nakanishi. Anti-cancer Effect of a Planar Catechin Analog through the Decrease in Mitochondrial Membrane Potential. ACS Medicinal Chemistry Letters. 2023. 14. 10. 1478-1481
  • Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki, Akira Sumiyoshi. Effects of X-ray irradiation on the redox status of mouse colorectal tissues. Advances in Redox Research. 2023. 8. 100067-100067
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MISC (83)：
  • Yoichi Takakusagi, Ryoma Kobayashi, Keita Saito, Shun Kishimoto, Murali C. Krishna, Ramachandran Murugesan, Ken-ichiro Matsumoto. EPR and Related Magnetic Resonance Imaging Techniques in Cancer Research. Metabolites. 2023. 13. 1. 69-69
  • Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Toshihiko Ozawa, Ken-ichiro Matsumoto, Shunichi Fukuzumi. pH Effect on the Scavenging Rates of Ascorbic Acid against Selected Radicals in Phosphate Buffer Solutions. Free Radical Biology and Medicine. 2022. 180. s64-s64
  • Ken-ichiro Matsumoto, Ikuo Nakanishi, Zhivko Zhelev, Rumiana Bakalova, Ichio Aoki. Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging. Antioxidants & Redox Signaling. 2021. 36. 1-3. 95-121
  • Ken-Ichiro Matsumoto, Megumi Ueno, Yoshimi Shoji, Ikuo Nakanishi. Heavy-ion beam-induced reactive oxygen species and redox reactions. Free radical research. 2021. 55. 4. 1-11
  • Ken-ichiro Matsumoto, James B. Mitchell, Murali C. Krishna. Multimodal Functional Imaging for Cancer/Tumor Microenvironments Based on MRI, EPRI, and PET. Molecules. 2021. 26. 6. 1614-1614
ｍore...
Books (2)：
  • 放射線の科学 : 生体影響および防御と除去
    東京化学同人 2012 ISBN:9784807907939
  • バイオサイエンスESR 1
    廣川書店 1996 ISBN:4567255208
Education (1)：
  • 1993 - 1996 Graduate School of Pharmaceutical Sciences, Showa University Pharmaceutical Scientific Research Division Doctoral course
Work history (9)：
  • 2021/04 - 現在 量子科学技術研究開発機構 量子生命・医学部門 放射線医学研究所 放射線規制科学研究部 障害分子機構解析研究グループ グループリーダー
  • 2019/04 - 2021/03 量子科学技術研究開発機構 量子医学・医療部門 放射線医学総合研究所 放射線障害治療研究部・障害分子機構解析研究グループ グループリーダー
  • 2016/04 - 2019/03 量子科学技術研究開発機構・放射線医学総合研究所 放射線障害治療研究部・障害分子機構解析研究チーム チームリーダー
  • 2011/04 - 2016/03 放射線医学総合研究所 重粒子医科学センター・先端粒子線生物研究プログラム・レドックス応答制御研究チーム チームリーダー
  • 2006/04 - 2011/03 放射線医学総合研究所 重粒子医科学センター・粒子線生物研究グループ・放射線効果修飾研究チーム 主任研究員
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Awards (5)：
  • 2017/06 - 日本酸化ストレス学会 学術賞
  • 2010/06 - 第10回AOB研究会 奨励賞
  • 2007/11 - 電子スピンサイエンス学会 奨励賞 ESRスペクトル-空間画像化法を中心とするESR機能画像化法の開発と応用
  • 2005/07 - EPR 2005 (A joint meeting of the 8th International EPR Spin Trapping Meeting and the 11th In Vivo EPR Spectroscopy and Imaging) Young Investigator Award
  • 2000/07 - The SFRR Japan Award for Young Scientists
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