YOKOYAMA TAKASHI

ヨコヤマタカシ | YOKOYAMA TAKASHI

Affiliation and department：
Job title：特任助教
Research theme for competitive and other funds (7)：

2021 - 2024 TRIB1 promotes metastasis through transcriptional activation of EMT-related genes
2018 - 2021 Inhibition of novel cancer specific antioxidant regulation promotes anticancer function
2017 - 2020 Reprogramming of metabolic networks in COP1-mediated oncogenesis
2013 - 2016 Trib1 is an important adaptor that connects the MAP kinase pathway with C/EBPa in leukemogenesis
2011 - 2014 Molecular basis of myeloid leukemogenesis

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Papers (17)：

Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa. The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation. Journal of Biological Chemistry. 2024. 300. 1. 105580-105580
Takashi Yokoyama, Takahito Kuga, Yuka Itoh, Shigeo Otake, Chiho Omata, Masao Saitoh, Keiji Miyazawa. Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β-induced cell motility. Journal of Biological Chemistry. 2023. 299. 2. 102820-102820
Daisuke Fujioka, Yosuke Watanabe, Takamitsu Nakamura, Takashi Yokoyama, Keiji Miyazawa, Makoto Murakami, Kiyotaka Kugiyama. Group V Secretory Phospholipase A<sub>2</sub> Regulates Endocytosis of Acetylated LDL by Transcriptional Activation of PGK1 in RAW264.7 Macrophage Cell Line. Journal of Atherosclerosis and Thrombosis. 2022. 29. 5. 692-718
Yoshitaka Sunami, Takashi Yokoyama, Seiko Yoshino, Tomoko Takahara, Yukari Yamazaki, Hironori Harada, Takuro Nakamura. BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes. Blood advances. 2021. 6. 6. 1827-1843
Mitsuyoshi Motizuki, Daizo Koinuma, Takashi Yokoyama, Yuka Itoh, Chiho Omata, Kohei Miyazono, Masao Saitoh, Keiji Miyazawa. TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity. Journal of Biological Chemistry. 2021. 296. 100545-100545

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