Rchr
J-GLOBAL ID:202001011350084825   Update date: May. 10, 2024

KAWAI TOMOKO

カワイ トモコ | KAWAI TOMOKO
Affiliation and department:
Job title: assistant professor
Research keywords  (7): physiology ,  reproductive system ,  nerves ,  mechanobiology ,  Medical and Biological Engineering ,  endocrinology ,  internal environment factors
Research theme for competitive and other funds  (12):
  • 2024 - 2027 Elucidation of the regulatory mechanism of sperm motility and fertility by the parasympathetic nervous and the demonstration using a sperm culture system
  • 2023 - 2025 Elucidation of the mechanism that regulate the sperm function by autonomic nerves and the development of the system to improve the sperm quality
  • 2024 - 2025 Elucidation of the mechanism of reproductive diseases caused by environment focusing on the novel oocyte-secreted factor.
  • 2023 - 2025 Elucidation of the mechanism that regulate the sperm motility by parasympathetic nerves and the development of the system to improve the sperm motility
  • 2023 - 2024 Creation of the fundamental technology for producing the high-quality of fertilized oocytes in mammals
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Papers (22):
  • Elesh IF, Marey MA, Zinnah MA, Akhtar I, Kawai T, Naim F, Goda W, Rawash ARA, Sasaki M, Shimada M, Miyamoto A. Peptidoglycan switches off the TLR2-mediated sperm recognition and triggers sperm localization in the bovine endometrium. Frontiers in Immunology. 2021
  • Nakanishi T, Tanaka R, Tonai S, Lee JY, Yamaoka M, Kawai T, Okamoto A, Shimada M, Yamashita Y. LH induces de novo cholesterol biosynthesis via SREBP activation in granulosa cells during ovulation in female mice. Endocrinology. 2021. 162. 11
  • Kawai T, Richards JS, Shimada M. Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. Communications Biology. 2021
  • Kawai T, Shimada M. Pretreatment of ovaries with collagenase before vitrification keeps the ovarian reserve by maintaining cell-cell adhesion integrity in ovarian follicles. Scientific reports. 2020. 10. 6841
  • Kawai T, Shimada M. The proliferation of granulosa cells during ovarian follicular development ~the regulatory mechanisms and the physiological roles to acquire the responsible ability to ovulation stimuli~. Journal of Mammalian Ova Research. 2020. 37. 1
more...
MISC (2):
  • 川合智子, Hoque SAM, JoAnne, S. Richards, 島田昌之. 卵胞直径の拡大で可能となる顆粒膜細胞のレチノイン酸合成がLH受容体発現を誘導. 日本生殖内分泌学会雑誌. 2020. 25. 21-23
  • 島田昌之, 川合智子, 星野由美. 卵胞発育の生理: 卵胞発育と卵成熟. 臨床婦人科産科. 2016. 70. 12. 1110-1116
Books (2):
  • SDGsに向けた生物生産学入門
    共立出版 2021
  • 妊孕性温存のすべて
    中外医学社 2021
Lectures and oral presentations  (46):
  • Changes of ovarian hardness and elasticity affect the development and function of secondary follicles
    (68th Annual Meeting of Biophysical Society 2024)
  • 生殖システムを司る新たな主要メカニズムの解明と生殖医療への展開
    (岡山大学みなす講演会 2023)
  • コラーゲンが豊富な卵胞周囲の硬さ環境が卵胞の発育と機能に果たす役割
    (神戸大学バイオシグナル総合研究センター大学院セミナー 2022)
  • 円形精子細胞の体外培養条件の検討
    (第78回九州・沖縄生殖医学会 2022)
  • 円形精子細胞の体外培養条件の検討
    (第66回 日本生殖医学会 2021)
more...
Education (3):
  • 2011 - 2015 Hiroshima University Graduate School of Biosphere Science
  • 2009 - 2011 Hiroshima University Graduate School of Biosphere Science
  • 2005 - 2009 Kindai University Faculty of Biology-oriented science and technology
Professional career (1):
  • Ph.D. (Agriculture) (Hiroshima University)
Work history (5):
  • 2023/05 - 現在 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences Assistant Professor
  • 2019/04 - 2022/04 Hiroshima University Graduate School of Integrated Sciences for Life Assistant Professor
  • 2015/04 - 2019/03 Hiroshima University Graduate School of Biosphere Science postdoctoral researcher
  • 2013/04 - 2015/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists DC2
  • 2011/10 - 2012/09 Innovation Training Program for Young Technical Experts Working Researcher
Committee career (2):
  • Okayama University Department of Animal Resources Usage Consultation Committee Member
  • Okayama University Education Program Committee Member in Basic or Social Medical field
Awards (8):
  • 2020 - 第24回 日本生殖内分泌学会 学術奨励賞
  • 2020 - 広島大学 大学院統合生命科学研究科奨励賞
  • 2019 - 第37回 日本受精着床学会世界体外受精会議記念賞
  • 2018 - 第59回 日本卵子学会 学術奨励賞
  • 2018 - 51st Society for the Study of Reproduction Annual Meeting Best international abstract award
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Association Membership(s) (12):
Biophysical Society ,  The American Society for Cell Biology ,  American Society for Reproductive Medicine ,  Society for the Study of Reproduction ,  Japanese Society for Medical and Biological Engineering ,  The Biophysical Society of Japan ,  The Physiological Society of Japan ,  Journal of Mammalian Ova Research ,  The Society for reproduction and development ,  Japan Society of Fertilization and Implantation ,  Japan society for reproductive medicine ,  Japan Society of Reproductive Endocrinology
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