Research keywords (6)：
Carcinoma in the elderly
, Microsatellite instability
, Geriatric patahology
, Gastric cancer
, Colorectal cancer
, Esophageal cacner
Research theme for competitive and other funds (16)：
2022 - 2025 Pathophysiology and treatment strategies based on genetic alterations in gastric cance in the elderlyr
2015 - 2018 Pathogenesis of COPD exacerbation and the proteins related to gap junction
2013 - 2017 Study on the pathological role of estrogens in colorectal cancer.
2013 - 2016 Investigation on pathogenesis and therapy of COPD with phenotypes of Marfan syndrome, especially on its relation to ECM malformation
2013 - 2016 Competing risks analysis for misclassified outcomes
2013 - 2016 Association of histological diversity and genetic alteration of gastric cancer in the elderly
2012 - 2015 The association between genetic variants identified by GWAS and prostate cancer risk and mortality
2010 - 2012 The association between genetic variations of the neuronal nicotinic cholinergic receptors and smoking-related lung diseases
2010 - 2012 Relation between estrogens and colorectal cancer among Japanese.
2010 - 2012 Epigenetic control of microRNA in the development gastric carcinomas in the elderly
2007 - 2008 Association between geriatric diseases and sex steroid hormones.
Show all
Papers (379)：
Keisuke Nonaka, Junko Aida, Yasuko Hasegawa, Tomio Arai, Toshiyuki Ishiwata, Kaiyo Takubo. Telomere Length Measurement in Human Tissue Sections by Quantitative Fluorescence In Situ Hybridization (Q-FISH). Methods in Molecular Biology. 2024. 9-14
Keisuke Nonaka, Akira Arakawa, Manato Hara, Akiko Komatsu, Takuya Nagasaka, Toshio Kumasaka, Seiya Kamino, Hirofumi Rokutan, Yuuki Shichi, Shigeo Murayama, et al. An Autopsy Case of Myotonic Dystrophy Type 1 With Pancreatic Intraductal Papillary Mucinous Neoplasm. Cureus. 2024
Tomoyasu Matsubara, Kenji Ishii, Yoko Saito, Aya Midori Tokumaru, Akira Arakawa, Manato Hara, Masanori Kurihara, Renpei Sengoku, Kazutomi Kanemaru, Atsushi Iwata, et al. Neurofibrillary tangle-predominant dementia followed by amyloid β pathology: a clinico-radio-pathological case providing insights into current disease-modifying therapeutic strategy. Acta neuropathologica communications. 2024. 12. 1. 98-98
Kei Ito, Naoko Honma, Hideaki Ogata, Akimitsu Yamada, Mika Miyashita, Tomio Arai, Eiichi Sasaki, Kazutoshi Shibuya, Tetuo Mikami, Masataka Sawaki. Clinicopathological importance of Bcl-2 and p53 in postmenopausal triple-negative breast carcinoma and association with age. Pathology international. 2024
Tetsuya Ito, Tatsuro Yamaguchi, Kensuke Kumamoto, Okihide Suzuki, Noriyasu Chika, Satoru Kawakami, Tomonori Nagai, Tsukasa Igawa, Kenji Fujiyoshi, Yoshito Akagi, et al. Incidence and molecular characteristics of deficient mismatch repair conditions across nine different tumors and identification of germline variants involved in Lynch-like syndrome. International Journal of Clinical Oncology. 2024. 29. 7. 953-963
Pathology of carcinoma of the esophagogastric zone
(2024)
Clinicopathological and definition of undifferentiated-type carcinoma: the Japanese pathologist’s view
(The 10th Korean International Gastric Cancer Association (KINGCA) WEEK 2023 2023)
Comparison between JGCA and WHO classification of signet ring cell and poorly cohesive carcinoma
(International Gastric Cancer Congress (IGCC) 2023 2023)
Classification of undifferentiated cancer; poorly cohesive, signet-ring cell, and poorly differentiated: Japanese Pathologist's view.
(Korean International Gastric Cancer (KINGCA) week 2021 2021)
Pathological diagnosis of microsatellite-unstable tumors
(2020)
2010/04 - 現在 Tokyo Metropolitan Institute for Geriatrics and Gerontology Department of Pathology Director
2015/04 - 2015/12 Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Research Team for Geriatric Pathology Research Director
2009/04 - 2010/03 Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Department of Pathology Vice Director
1996/04 - 2008/03 Tokyo Metropolitan Geriatric Hospital Department of Pathology Chief
1991/04 - 1996/03 Hamamatsu University School of Medicine Department of Pathology Assistant Professor
1993/06 - 1995/05 University of Queensland, Australia Department of Pathology Visiting Research Fellow
1988/04 - 1991/03 Fujieda Municipal Shida General Hospital Pathology Medical staff
Show all
Committee career (2)：
2012/06 - 2018/06 Japanese Esophageal Society Director
2016/03 - 2018/03 Japanese Gastric Cancer Association Director
Awards (3)：
2023/06 - 12 th International Association of Geriatrics and Gerontology Asia/Oceania Regional Congress 2023 Outstanding Poster Presentation Award Age-related increase of proportion of microsatellite instability in gastric, colorectal, and endometrial carcinomas
2020/11 - Japanese Society of Pathology Pathological Diagnosis Award Diagnostic pathology of microsatellite-unstable tumors
2004/12 - Japanese Society of Pathology Pathology Research Award Clinicopathological and molecular characteristics of gastrointestinal carcinomas in the elderly
Association Membership(s) (8)：
Japanese Esophageal Society
, Japanese Gastric Cancer Association
, Japanese Society of Laboratory Medicine
, Japan Geriatrics Society
, Japanese Division of International Academy of Pathology
, Japanese Society of Clinical Cytology
, Japanese Cancer Association
, Japanese Society of Pathology
