Rchr
J-GLOBAL ID：202001011795198367
Update date: Nov. 29, 2024
Sekiguchi Masahiro
セキグチ マサヒロ | Sekiguchi Masahiro
Affiliation and department：
Research field (3)：
Hematology and oncology
, Fetal medicine/Pediatrics
, Tumor biology
Research theme for competitive and other funds (2)：
- 2021 - 2023 間葉系幹細胞の胚葉起源に基づくユーイング肉腫の新規分類法の確立とその応用
- 2018 - 2020 Multiomics analysis of hepatoblastoma
Papers (42)：
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Shota Kato, Aiko Sato-Otsubo, Wataru Nakamura, Masahiro Sugawa, Ai Okada, Kenichi Chiba, Nao Takasugi, Tomoya Irikura, Moe Hidaka, Masahiro Sekiguchi, et al. Genome profiling with targeted adaptive sampling long-read sequencing for pediatric leukemia. Blood Cancer Journal. 2024. 14. 1
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Shutaro Inoue, Yoshiko Nakano, Mariko Tanaka, Yuta Yamada, Kentaro Watanabe, Moe Hidaka, Masahiro Sekiguchi, Shota Kato, Takeyuki Watadani, Jun Fujishiro, et al. DICER1 syndrome with an intronic germline variant causing splice alteration. Pediatric blood & cancer. 2024. 71. 8. e31055
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Shota Kato, Keita Chagi, Yusuke Takagi, Moe Hidaka, Shutaro Inoue, Masahiro Sekiguchi, Natsuho Adachi, Kaname Sato, Hiroki Kawai, Motohiro Kato. Machine/deep learning-assisted hemoglobin level prediction using palpebral conjunctival images. British journal of haematology. 2024
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Kentaro Watanabe, Keiji Tasaka, Hideto Ogata, Shota Kato, Hiroo Ueno, Katsutsugu Umeda, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Shunsuke Kimura, et al. Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK signaling and cell cycle progression. Cancer Gene Therapy. 2024
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Amélie Roehrig, Theo Z Hirsch, Aurore Pire, Guillaume Morcrette, Barkha Gupta, Charles Marcaillou, Sandrine Imbeaud, Christophe Chardot, Emmanuel Gonzales, Emmanuel Jacquemin, et al. Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma. Nature communications. 2024. 15. 1. 3031-3031
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MISC (26)：
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Ryota Shirai, Tomoo Osumi, Keita Terashima, Chikako Kiyotani, Meri Uchiyama, Shinichi Tsujimoto, Masanori Yoshida, Kaoru Yoshida, Toru Uchiyama, Daisuke Tomizawa, et al. PREVALENCE OF GERMLINE VARIANTS IN SMARCB1 INCLUDING SOMATIC MOSAICISM IN AT/RT AND OTHER RHABDOID TUMORS. NEURO-ONCOLOGY. 2020. 22. 277-278
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久保田 泰央, 関 正史, 関口 昌央, 吉田 美沙, 吉田 健一, 樋渡 光輝, 宮野 悟, 岡 明, 林 泰秀, 田中 祐吉, et al. ターゲットキャプチャー法による小児胚細胞腫瘍の変異解析. 日本小児科学会雑誌. 2019. 123. 2. 263-263
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Masahiro Sekiguchi, Junko Takita. Comprehensive genomic analysis of hepatoblastoma reveals its genetic heterogeneity and provides novel therapeutic targets. The Japanese Journal of Pediatric Hematology/Oncology. 2019. 56. 5. 361-369
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Yuji Yamada, Shota Kato, Ryota Shirai, Tomoo Osumi, Chikako Kiyotani, Toshihiko Watanabe, Tomoro Hishiki, Masahiro Sekiguchi, Masafumi Seki, Junko Takita, et al. Sibling Cases of Pleuropulmonary Blastoma with Compound Heterozygous DICER1 Mutations. PEDIATRIC BLOOD & CANCER. 2018. 65. S74-S75
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樋渡 光輝, 渡邉 健太郎, 木村 俊介, 関口 昌央, 久保田 泰央, 岡 明, 滝田 順子. 造血器および固形腫瘍におけるSTAT3阻害剤、cucurbitacin Iの抗腫瘍効果の検討(Cucurbitacin I, JAK-STAT signaling pathway inhibitor with antitumor activity against cancer cells). 臨床血液. 2018. 59. 9. 1700-1700
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Lectures and oral presentations (4)：
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Fundamentals for Genetic Research Projects in Pediatric Oncology
(2019)
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Comprehensive genetic and epigenetic analyses identify high expression of ODC1 as a therapeutic target in high-risk hepatoblastoma
(2018)
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Comprehensive epigenetic analysis identifies NQO1 as a potential therapeutic target of high-risk hepatoblastoma
(2018)
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Genetic and Epigenetic Analyses of Hepatoblastoma Identify Subgroups with Different Clinical and Biological Features
(The 49th Congress of the International Society of Paediatric Oncology (SIOP 2017) 2017)
Education (3)：
- 2016 - 2020 The University of Tokyo Graduate School of Medicine Reproductive, Developmental and Aging Sciences
- 2005 - 2009 The University of Tokyo Faculty of Medicine School of Medicine
- 2003 - 2005 The University of Tokyo College of Arts and Sciences Natural sciences III
Association Membership(s) (6)：
日本人類遺伝学会
, 日本癌学会
, 日本血液学会
, 日本造血細胞移植学会
, 日本小児血液・がん学会
, 日本小児科学会
