Rchr
J-GLOBAL ID：202001012810350525   Update date: Aug. 27, 2024

Kawano Mitsuo

Kawano Mitsuo
Research theme for competitive and other funds  (25)：
  • 2021 - 2025 Establishing the type I CRISPR platform for extra chromosome elimination through epigenetic modulation
  • 2021 - 2024 新規経鼻噴霧型SARS-CoV-2ワクチンの開発
  • 2018 - 2021 Development of a novel membrane immune-induced infectious virus enteritis vaccine
  • 2016 - 2019 Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complications
  • 2015 - 2017 Development of the noninvasive nasal spray vaccine for prevention of cervical cancer using the next generation type virus vector.
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Papers (50)：
  • Kae Sakai-Sugino, Jun Uematsu, Hidetaka Yamamoto, Sahoko Kihira, Mitsuo Kawano, Miwako Nishio, Masato Tsurudome, Hidehisa Sekijima, Myles O'Brien, Hiroshi Komada. Inhibitory effects of kaempferol, quercetin and luteolin on the replication of human parainfluenza virus type 2 in vitro. Drug discoveries & therapeutics. 2024
  • Jun Uematsu, Kae Sakai-Sugino, Sahoko Kihira-Nakanishi, Hidetaka Yamamoto, Kazuyuki Hirai, Mitsuo Kawano, Miwako Nishio, Masato Tsurudome, Myles O'Brien, Hiroshi Komada. Inhibitions of human parainfluenza virus type 2 replication by ribavirin and mycophenolate mofetil are restored by guanosine and S-(4-nitrobenzyl)-6-thioinosine. Drug discoveries & therapeutics. 2019. 13. 6. 314-321
  • Takahiro Nagatake, Hidehiko Suzuki, So-Ichiro Hirata, Naomi Matsumoto, Yasuko Wada, Sakiko Morimoto, Ayaka Nasu, Michiko Shimojou, Mitsuo Kawano, Kentaro Ogami, et al. Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice. International immunology. 2018. 30. 10. 471-481
  • Kae Sakai-Sugino, Jun Uematsu, Miyuki Kamada, Hiroe Taniguchi, Saori Suzuki, Yumiko Yoshimi, Sahoko Kihira, Hidetaka Yamamoto, Mitsuo Kawano, Masato Tsurudome, et al. Glycyrrhizin inhibits human parainfluenza virus type 2 replication by the inhibition of genome RNA, mRNA and protein syntheses. Drug discoveries & therapeutics. 2017. 11. 5. 246-252
  • Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, et al. Restrictive IL-10 induction by an innocuous parainfluenza virus vector ameliorates nasal allergy. The Journal of allergy and clinical immunology. 2017. 139. 2. 682-686
ｍore...
MISC (3)：
  • Takahiro Nagatake, Yasuko Wada, Naomi Matsumoto, Michiko Shimojou, Soichiro Hirata, Ayaka Nasu, Hidehiko Suzuki, Koji Hosomi, Kentaro Ogami, Yusuke Tsujimura, et al. Inducible bronchus-associated lymphoid tissue plays an important role in the induction of antigen-specific immune response by Ag85B-hPIV2-based anti-tuberculosis vaccine in mice. JOURNAL OF IMMUNOLOGY. 2016. 196
  • Hiroshi Komada, Akiyo Imai, Morihiro Ito, Hideki Tsumura, Jun Uematsu, Mitsuo Kawano, Machiko Nishio, Masato Tsurudome, Yasuhiko Ito. Regulation of lymphocyte activation through CD98 is independent of IL-2-IL-2R system. CELL STRUCTURE AND FUNCTION. 2004. 29. 87-87
  • Machiko Nishio, Masato Tsurudome, Morihiro Ito, Noriko Watanabe, Mitsuo Kawano, Hiroshi Komada, Yasuhiko Ito. Human parainfluenza virus type 2 phosphoprotein: Mapping of monoclonal antibody epitopes and location of the multimerization domain. Journal of General Virology. 1997. 78. 6. 1303-1308
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