Rchr
J-GLOBAL ID：202001012955598193
Update date: Aug. 28, 2024
TATSUMI Toshifumi
Tatsumi Toshifumi | TATSUMI Toshifumi
Affiliation and department：
Research field (2)：
Radiology
, Pharmaceuticals - chemistry and drug development
Research keywords (5)：
α線放出核種
, 抗体薬物複合体
, プレターゲティング治療
, 不斉触媒反応
, 有機合成化学
Research theme for competitive and other funds (6)：
Papers (14)：
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Toshifumi Tatsumi, Songji Zhao, Akitomo Kasahara, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Tatsuhiko Kodama, Kazuhiro Takahashi, Akira Sugiyama, Kohshin Washiyama, et al. In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin. Bioorganic & Medicinal Chemistry Letters. 2024. 129803-129803
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Kenji Shimazoe, Kim Donghwan, Tomoko Mineo, Takeshi Sato, Seiichi Ohta, Toshifumi Tatsumi, Akira Sugiyama, Kenzo Yamatsugu, Sachiyo Nomura, Ryohei Terabayashi, et al. pH dependence of perturbed angular correlation in DOTA chelated $$^{111}$$In measured with ring-shape gamma-ray detectors. Interactions. 2024. 245. 1
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Toshifumi Tatsumi, Koki Sasamoto, Takuya Matsumoto, Ryo Hirano, Kazuki Oikawa, Masato Nakano, Masaru Yoshida, Kounosuke Oisaki, Motomu Kanai. Practical N-to-C peptide synthesis with minimal protecting groups. Communications Chemistry. 2023. 6. 1
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Juri Sakata, Toshifumi Tatsumi, Akira Sugiyama, Akihiro Shimizu, Yuya Inagaki, Hiroto Katoh, Takefumi Yamashita, Kazuki Takahashi, Sho Aki, Yudai Kaneko, et al. Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin. Protein expression and purification. 2023. 106375-106375
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Yudai Kaneko, Kenzo Yamatsugu, Takefumi Yamashita, Kazuki Takahashi, Toshiya Tanaka, Sho Aki, Toshifumi Tatsumi, Takeshi Kawamura, Mai Miura, Masazumi Ishii, et al. Pathological complete remission of relapsed tumor by photo-activating antibody-mimetic drug conjugate treatment. Cancer Science. 2022. 113. 12. 4350-4362
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MISC (24)：
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巽俊文, 山次健三, 杉山暁, 趙松吉, 粟生木美穂, 西嶋剣一, 右近直之, 下山彩希, 譚成博, 城寶大輝, et al. 低免疫原性ストレプトアビジン変異体と改変ビオチンを用いるプレターゲティングシステムの開発. 放射化学. 2023. 47
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Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki, Taiki Joho, et al. Synthesis and Astatine Labeling of a bis-iminobiotin derivative with enhanced plasma stability. NUCLEAR MEDICINE AND BIOLOGY. 2022. 108. S121-S121
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山次健三, 高橋和希, 加藤洋人, 山下雄史, 安藝翔, 巽俊文, 金子雄大, 川村猛, 三浦麻衣, 石井正純, et al. Antibody-Mimetic Drug Conjugate: AMDC comprised of modified streptavidin and bisiminobiotin, and its use in near-infrared phototherapy. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)
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巽俊文, 山次健三, 杉山暁, ZHAO S., 粟生木美穂, 西嶋剣一, 右近直之, 下山彩希, GAO F., 城寶大輝, et al. Development of pre-targeting system using low immunogenic streptavidin mutants and 211-At-labeled bis-iminobiotin. 日本放射化学会討論会(Web). 2022. 66th
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高橋和希, 山次健三, 加藤洋人, 山下雄史, 安藝翔, 巽俊文, 金子雄大, 川村猛, 川村猛, 三浦麻衣, et al. Near-infrared Phototherapy Using Modified Streptavidin-iminobiotin Drug Delivery System. 日本薬学会年会要旨集(Web). 2022. 142nd
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Patents (4)：
Education (2)：
- 2012 - 2017 兵庫県立大学大学院 物質理学研究科
- 2008 - 2012 University of Hyogo School of Science Department of Material Science
Professional career (1)：
Work history (4)：
- 2023/12 - 現在 The University of Tokyo
- 2021/04 - 2023/11 東京大学大学院薬学系研究科 特別研究員
- 2021/04 - 2023/11 日本学術振興会特別研究員PD
- 2017/04 - 2023/11 東京大学大学院 薬学系研究科 博士研究員
Awards (1)：
- 2022/09 - 日本放射化学会第66回討論会 若手優秀発表賞
Association Membership(s) (3)：
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