Research keywords (5)：
Sex difference
, meiosis
, Germ cell
, Developmental Biology
, mouse
Research theme for competitive and other funds (2)：
2022 - 2025 ノンカノニカルTF IIDによる生殖細胞特異的な転写活性化機構の解明
2020 - 2022 The female specific transcriptional regulation in murine meiosis
Papers (10)：
Kris G. Alavattam, Jasmine M. Esparza, Mengwen Hu, Ryuki Shimada, Anna R. Kohrs, Hironori Abe, Yasuhisa Munakata, Kai Otsuka, Saori Yoshimura, Yuka Kitamura, et al. ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline. Genes & Development. 2024. 38. 3-4. 115-130
Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro. STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nature Communications. 2023. 14. 1
Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Naoki Tani, et al. Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. bioRxiv. 2023
Ryuki SHIMADA, Kei-ichiro ISHIGURO. Cell cycle regulation for meiosis in mammalian germ cells. Journal of Reproduction and Development. 2023. 69. 3. 139-146
Kei-ichiro Ishiguro, Ryuki Shimada. MEIOSIN directs initiation of meiosis and subsequent meiotic prophase program during spermatogenesis. Genes & Genetic Systems. 2022. 97. 1. 27-39
Exploring the murine germ cell masculinization mechanism using scRNA-seq
(52nd Annual Meeting of the Japanese Society of Developmental Biologists 2019)
To explore the feminizing genes mediated by SMAD4 in germ cell
(Joint Annual Meeting of JSDB51st and JSCB 70th 2018)
Requirement of DDX6-mediated P-body formation in male germ cell development
(50th Annual Meeting of the Japanese Society of Developmental Biologists 2017)
Education (1)：
2015 - 2020 The Graduate University for Advanced Studies School of Life Science Department of Genetics
Professional career (1)：
博士(理学) (総合研究大学院大学)
Work history (3)：
2022/06 - 現在 Kumamoto University Institute of Molecular Embryology and Genetics assistant professor
2020/07 - 2022/05 Kumamoto University Institute of Molecular Embryology and Genetics
2020/04 - 2020/06 National Institute of Genetics Department of Gene Function and Phenomics, Mammalian Development Laboratry Project Researcher
Awards (7)：
2023/09 - 日本遺伝学会 Best Papers賞
2020/03 - School of Life Science, SOKENDAI School of Life Science Dean's Award The molecular dissection of NANOS2 function required for male germ cell differentiation
2020/03 - Department of Genetics, School of Life Science, SOKENDAI Morishima Award The molecular dissection of NANOS2 function required for male germ cell differentiation
2019/05 - The Japanese Society of Developmental Biologists Best Poster Award Exploring the murine germ cell masculinization mechanism using scRNA-Seq data
2019/03 - Department of Genetics, School of Life Science, SOKENDAI Hiroko Morishima Progress Award Analysis of male germ cell differentiation regulating gene network using scRNA-Seq
2017/07 - Best Poster Award Role of DDX6-mediated P-body formation in NANOS2 function
2016/10 - 2016 Life Science Retreat Committee 2016 Life Science Retreat Gold Award Requirement of DDX6-mediated P-body formation for the Nanos2 function
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Association Membership(s) (3)：
The Genetics Society of Japan
, The Molecular Biology of Japan
, The Japanese Society of Developmental Biologists
