Nakagomi Takayuki

Nakagomi Takayuki | Nakagomi Takayuki

Affiliation and department：
Job title： Professor

Research field (3)： Neuropathology , Neuroscience - general , Cell biology

Research keywords (1)：神経再生、幹細胞、脳傷害、脳梗塞、細胞治療、ぺリサイト

Research theme for competitive and other funds (20)：

2023 - 2026 脳梗塞後の組織修復・再生における脳傷害/虚血誘導性幹細胞による老廃物除去の役割
2022 - 2025 Cell therapy research using human umbilical cord blood-derived hemangioblast-like cells for the treatment of cerebral infarction
2021 - 2025 播種性癌に対する革新的な自殺遺伝子ウイルス療法の開発
2019 - 2022 Novel treatment for intracranial hemorrhage using amnion derived mesenchymal stem cells
2019 - 2022 Development of virotherapy for osteosarcoma pulmonary metastases using stem cells as carriers

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Papers (74)：

Takayuki Nakagomi. Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration. Neural Regeneration Research. 2025
Shuichi Tanada, Takayuki Nakagomi, Akiko Nakano-Doi, Toshinori Sawano, Shuji Kubo, Yoji Kuramoto, Kazutaka Uchida, Kenichi Yamahara, Nobutaka Doe, Shinichi Yoshimura. Human-Brain-Derived Ischemia-Induced Stem Cell Transplantation Is Associated with a Greater Neurological Functional Improvement Compared with Human-Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Mice After Stroke. International Journal of Molecular Sciences. 2024
Takayuki Nakagomi, Aya Narita, Hideaki Nishie, Akiko Nakano-Doi, Toshinori Sawano, Yu Fukuda, Tomohiro Matsuyama. L-PGDS-PGD2-DP1 Axis Regulates Phagocytosis by CD36+ MGs/MΦs That Are Exclusively Present Within Ischemic Areas After Stroke. Cells. 2024. 13. 20
Yuka Okinaka, Mitsuyo Maeda, Yosky Kataoka, Takayuki Nakagomi, Akiko Nakano-Doi, Johannes Boltze, Carsten Claussen, Sheraz Gul, Akihiko Taguchi. Direct water-soluble molecules transfer from transplanted bone marrow mononuclear cell to hippocampal neural stem cells. Stem cells and development. 2024
Shuichi Fujiwara, Akiko Nakano-Doi, Toshinori Sawano, Shuji Kubo, Nobutaka Doe, Takayuki Nakagomi. Administration of Human-Derived Mesenchymal Stem Cells Activates Locally Stimulated Endogenous Neural Progenitors and Reduces Neurological Dysfunction in Mice after Ischemic Stroke. Cells. 2024

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MISC (20)：

中込隆之, 松山知弘, 吉村紳一. 脳卒中における治験とエビデンスの創出脳傷害/虚血誘導性幹細胞最新の知見と神経再生療法への展望. 神経治療学. 2022. 39. 3. 356-356
別府幹也, Rajbhandari Saujanya, 中込隆之, 高木俊範, 土居亜紀子, 松山知弘, 吉村紳一. ヒト脳梗塞巣から脳傷害時にのみ誘導される幹細胞(injury-induced multipotent stem cells:iSCs)とMesenchymal stem cells(MSCs)の特性比較. 先進医薬研究振興財団研究成果報告集. 2021. 2020年度. 234-235
中込隆之. 脳傷害・虚血誘導性幹細胞を用いた新規神経再生療法の展望. 兵庫医科大学医学会雑誌. 2019. 43. 2. 1-8
Mikiya Beppu, Takayuki Nakagomi, Toshinori Takagi, Akiko Nakano-Doi, Rika Sakuma, Yoji Kuramoto, Kotaro Tatebayashi, Tomohiro Matsuyama, Shinichi Yoshimura. Abstract TP143: Potential of Cerebellum-derived Stem Cells in Human Brain to Regenerate Functional Neurons Following Ischemic Stroke. Stroke. 2019. 50. Suppl{\_}1
高木俊範, 吉村紳一, 中込隆之, 松山知弘. 【神経疾患の再生医療】神経・筋幹細胞による研究傷害誘導性神経・多能性幹細胞. Clinical Neuroscience. 2018. 36. 3. 346-350

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Patents (4)：

Books (5)：

脳梗塞病後の組織修復・神経再生における傷害/虚血誘導性幹細胞の役割
(株)ニュー・サイエンス社 2023
【最新臨床脳卒中学[上]-最新の診断と治療-】治療戦略を目指した研究再生・移植基礎研究脳軟膜由来傷害誘導性神経幹細胞
(株)日本臨床社 2014
Ischemia-induced neural stem/progenitor cells within the post-stroke cortex in adult brains, Neural Stem Cells and Therapy
InTech-Open Access Publisher. Chapter 16, 343-358 2012
Neurogenesis in the cerebral cortex after stroke.
Springer Science+Business Media B.V. (Vol. 2), Chapter 22, 211-217 2012
The Therapeutic Potential of Neural Stem Cells in Cerebral Ischemia
BENTHAM SCIENCE PUBL LTD 2011

Lectures and oral presentations (102)：

脳梗塞後に出現する特殊なミクログリアが壊死組織排出に与える影響
(日本解剖学会総会・全国学術集会抄録集(CD-ROM) 2024)
フィーダー細胞OP9を用いた効率的M2マクロファージ・Angiogenesis-inducing cells(AiC)の誘導
(日本再生医療学会総会(Web) 2024)
「細胞療法update」脳傷害/虚血誘導性幹細胞を用いた新規細胞治療開発の現状と展望
(脳循環代謝 2023)
新生児期と成体期の発症時期の異なるマウス脳梗塞モデルを用いた神経再生機構の解明
(脳循環代謝 2023)
Mechanism of necrotic tissue drainage after cerebral ischemia
(Proceedings for Annual Meeting of The Japanese Pharmacological Society 2023)

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Education (2)：

Professional career (1)：

Awards (5)：

Association Membership(s) (7)：

日本消化器病学会 , 日本呼吸器学会 , 日本再生医療学会 , 日本神経科学学会 , 日本脳循環代謝学会 , 日本神経学会 , 日本内科学会

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