Ito Emiko

Affiliation and department：
Research theme for competitive and other funds (4)：

2024 - 2027 HLAノックアウトiPS細胞を用いた心筋再生治療法の開発
2024 - 2027 デザイナー細胞による重症心不全に対する次世代型細胞治療の開発
2021 - 2024 LVAD装着患者におけるヒストン修飾による心機能回復メカニズムの解明
2021 - 2024 同種異系iPS心筋細胞移植治療に対するiPS間葉系幹細胞を用いた免疫抑制法の開発

Papers (33)：

Moyu Hasegawa, Kenji Miki, Takuji Kawamura, Ikue Takei Sasozaki, Yuki Higashiyama, Masaru Tsuchida, Kunio Kashino, Masaki Taira, Emiko Ito, Maki Takeda, et al. Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy. Development, growth & differentiation. 2024
Yuji Tominaga, Takuji Kawamura, Emiko Ito, Maki Takeda, Akima Harada, Kosuke Torigata PhD, Ryoto Sakaniwa, Yoshiki Sawa, Shigeru Miyagawa. Pleiotropic effects of extracellular vesicles from induced pluripotent stem cell-derived cardiomyocytes on ischemic cardiomyopathy: A pre-clinical study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2023
Junjun Li, Xiang Qu, Li Liu, Lingjun Li, Ying Hua, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Nagako Sougawa, et al. Developing Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction. Advanced Fiber Materials. 2023
Emiko Ito, Ai Kawamura, Takuji Kawamura, Maki Takeda, Akima Harada, Noriko Mochizuki-Oda, Yoshiki Sawa, Shigeru Miyagawa. Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction model. Scientific reports. 2023. 13. 1. 10530-10530
Takuji Kawamura, Yoshito Ito, Emiko Ito, Maki Takeda, Tsubasa Mikami, Takura Taguchi, Noriko Mochizuki-Oda, Masao Sasai, Tomomi Shimamoto, Yukako Nitta, et al. Safety confirmation of induced pluripotent stem cell-derived cardiomyocyte patch transplantation for ischemic cardiomyopathy: first three case reports. Frontiers in cardiovascular medicine. 2023. 10. 1182209-1182209

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MISC (54)：

Maki Takeda, Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Akima Harada, Noriko Mochizuki-oda, Yoshiki Sawa. Disease Specific Induced Pluripotent Stem Cell Derived Cardiomyocytes Represent Pathophysiological Phenotype in Hypertrophic Cardiomyopathy. CIRCULATION. 2020. 142
武田真季, 宮川繁, 伊東絵望子, 原田明希摩, 小田紀子[望月], 明石満, 澤芳樹. ヒトiPS細胞由来心筋細胞を用いた三次元心筋組織体の作製. 人工臓器. 2019. 48. 2. S-200
伊東絵望子, 宮川繁, 河村愛, 武田真季, 河村拓史, 小田紀子[望月], 澤芳樹. 臨床応用に向けたヒトiPS細胞由来心筋細胞移植における安全性評価方法の構築. 人工臓器. 2019. 48. 2. S-201
Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Noriko Mochizuki-Oda, Mitsuru Akashi, Yoshiki Sawa. Development of Innovate Drug Screening System Using Three Dimensional Cardiac Tissues Combined With Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells and Cardiac Component Cells. CIRCULATION. 2018. 138
Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Kazumasa Minami, Noriko Mochizuki-Oda, Yoshiki Sawa. Irradiation Eliminates Residual Induced Pluripotent Stem (iPS) Cells in Cardiomyocytes Derived From Human iPS Cells. CIRCULATION. 2018. 138

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