Rchr
J-GLOBAL ID：202001013720005949   Update date: Feb. 01, 2024

SUZUKI YASUHIRO

スズキ ヤスヒロ | SUZUKI YASUHIRO
Affiliation and department：
Tohoku University New Industry Creation Hatchery Center

About Tohoku University New Industry Creation Hatchery Center


Research field  (3)： Tumor biology ,  Fetal medicine/Pediatrics ,  Hematology and oncology
Research keywords  (13)： 膵がん ,  Intractable cancer ,  Vasohibin ,  Tumor malignancy ,  Post-translational modifications of microtubules ,  α-tubulin detyrosination ,  tumor immunity ,  SVBP ,  Angiogenesis ,  Rhabdomyosarcoma ,  antisense oligo ,  Peptide vaccine ,  LLPS
Research theme for competitive and other funds  (13)：
  • 2022 - 2025 Reprogramming the tumor microenvironment is the key for tumor treatment
  • 2021 - 2024 Vasohibin-2による横紋筋肉腫の悪性化制御機構の解明と新規治療法の開発
  • 2019 - 2022 Study for the structure and function of vasohibin-2 on cancer progression
  • 2018 - 2021 Analysis of the role of Vasohibi-2 in rhabdomyosarcoma and development of novel cancer therapy
  • 2018 - 2021 Reprogramming the tumor microenvironment to establish novel strategies and approaches for cancer therapy
Show all
Papers (43)：
  • Taketo Sasaki, Kohei Shigeta, Shuji Kitahara, Yasuhiro Suzuki, Shimpei Matsui, Ryo Seishima, Koji Okabayashi, Dan G Duda, Yuko Kitagawa. Inhibition of STAT3 Promotes Effector T Cell Infiltration But also Immunosuppression in the HCC Tumor Microenvironment. Anticancer research. 2022. 42. 11. 5205-5215
  • Miho Kobayashi, Ikumi Wakabayashi, Yasuhiro Suzuki, Kashio Fujiwara, Masanori Nakayama, Tetsuro Watabe, Yasufumi Sato. Tubulin carboxypeptidase activity of vasohibin-1 inhibits angiogenesis by interfering with endocytosis and trafficking of pro-angiogenic factor receptors. Angiogenesis. 2021. 24. 1. 159-176
  • Akihito Ikeda, Seia Urata, Tadashi Ando, Yasuhiro Suzuki, Yasufumi Sato, Tatsuya Nishino. The crystal structure of the tetrameric human vasohibin-1-SVBP complex reveals a variable arm region within the structural core. Acta Crystallographica Section D: Structural Biology. 2020. 76. Pt 10. 993-1000
  • 北原 秀治, 鈴木 康弘. 抗血管新生療法は胃がんにおける免疫抑制微小環境を改善できるか?(Does Anti-Vascular Therapy Reprogram the Immunosuppressive Microenvironment in Gastric Cancer?). 東京女子医科大学雑誌. 2019. 89. 臨増1. E100-E109
  • Rie Iida-Norita, Minaho Kawamura, Yasuhiro Suzuki, Shin Hamada, Atsushi Masamune, Toru Furukawa, Yasufumi Sato. Vasohibin-2 plays an essential role in metastasis of pancreatic ductal adenocarcinoma. Cancer Science. 2019. 110. 7. 2296-2308
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MISC (9)：
  • 小林 美穂, 若林 育海, 藤原 花汐, 鈴木 康弘, 中山 雅敬, 佐藤 靖史, 渡部 徹郎. Vasohibin-1が誘導する微小管の翻訳後修飾を介した受容体エンドサイトーシス阻害と新規脈管新生抑制機構. リンパ学. 2021. 44. 2. 65-69
  • 小林美穂, 小林美穂, 若林育海, 若林育海, 鈴木康弘, 鈴木康弘, 藤原花汐, 中山雅敬, 佐藤靖史, 佐藤靖史, et al. Vasohibin-1による微小管の翻訳後修飾を介したシグナル伝達の調節機構. 口腔病学会雑誌. 2021. 88. 1
  • 川村 美夏帆, 飯田 理恵, 鈴木 康弘, 濱田 晋, 正宗 淳, 古川 徹, 佐藤 靖史. Vasohibin-2は膵癌の浸潤・転移において重要な役割を果たす(Vasohibin-2 plays essential role in invasion and metastasis of pancreatic ductal adenocarcinoma). 日本癌学会総会記事. 2018. 77回. 1017-1017
  • 村瀬友里香, 村瀬友里香, 村瀬友里香, 青山絵理子, 鈴木康弘, 佐々木朗, 久保田聡, 久保田聡, 佐藤靖史, 滝川正春. CCN2-VASH1-SOD2 axisを介した内軟骨性骨化調節機構. 日本軟骨代謝学会プログラム・抄録集. 2018. 31st
  • 小柳 貴裕, 鈴木 康弘, 高橋 詳史, 嵯峨 泰, 鈴木 光明, 佐藤 靖史. 新規血管新生調節因子バゾヒビン2を標的とした卵巣癌治療応用に関する基礎研究. 産婦人科の実際. 2015. 64. 2. 217-221
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Books (2)：
  • モデル動物の作製と利用 : 循環器疾患 2021
    エル・アイ・シー 2021 ISBN:9784900487581
  • 新・血栓止血血管学
    金芳堂 2015
Lectures and oral presentations  (63)：
  • Propose and demonstration of novel chimeric artificial nucleic acids strategy and investigation of RNase H mediated target RNA cleavage activity
    (日本化学会春季年会講演予稿集(Web) 2022)
  • Understanding of a spatiotemporal regulation of α-tubulin detyrosination
    (日本分子生物学会年会プログラム・要旨集(Web) 2021)
  • Screening of small chemical compounds suppressing interaction between vasohibin-2 and SVBP
    (日本分子生物学会年会プログラム・要旨集(Web) 2021)
  • Development of novel cancer therapy targeting α-tubulin detyrosinating enzyme, Vasohibin-2
    (日本分子生物学会年会プログラム・要旨集(Web) 2021)
  • Studies on Synthesis and Property of Chimeric Artificial Nucleic Acid Conjugated with DNA for Catalytic Target Vasohibin2 RNA Cleavage-1
    (日本核酸医薬学会年会講演要旨集(CD-ROM) 2021)
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Education (3)：
  • 1997 - 2000 University of Tsukuba
  • 1995 - 1997 University of Tsukuba Master's Program in Biosystem Studies
  • 1990 - 1994 Yamagata University Faculty of Science Department of Biology
Professional career (1)：
  • Doctor of Philosophy (University of Tsukuba)
Work history (9)：
  • 2019/04 - Tohoku University New Industry Creation Hatchery Center
  • 2011/04 - 2019/03 Tohoku University Institute of Development, Aging and Cancer
  • 2010/04 - 2011/03 Tohoku University Institute of Development, Aging and Cancer
  • 2008/04 - 2010/03 Tohoku University Institute of Development, Aging and Cancer
  • 2006/04 - 2008/03 Tohoku University Institute of Development, Aging and Cancer
Show all
Committee career (1)：
  • - 現在 Japanese Vascular Biology and Medicine Organization a member of committee
Awards (2)：
  • 2000 - 日本血管細胞生物学会 International Vascular Biology Meeting 2000 フェローシップ受賞
  • 1999 - 日本血管細胞生物学会 Young Investigator Award優秀賞受賞
Association Membership(s) (3)：
Molecular Biology Society of Japan ,  Japanese Cancer Association ,  The Japanese Vascular Biology and Medicine Organization
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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