Rchr
J-GLOBAL ID:202001013727858823   Update date: Oct. 10, 2023

Hayakawa Hiroko

ハヤカワ ヒロコ | Hayakawa Hiroko
Affiliation and department:
Other affiliations (1):
  • Jichi Medical University
Research field  (1): Pathobiochemistry
Research keywords  (1): 喘息 アレルギー シグナル伝達 IL-33 自然リンパ球
Research theme for competitive and other funds  (4):
  • 2023 - 2026 肥満による好酸球性喘息悪化の機序の解明
  • 2018 - 2021 喘息発症におけるシグナル伝達p38-MK2経路の役割解明
  • 2018 - 2019 気管支喘息発症の性差に着目した新規治療法の開発
  • 2014 - 2017 A new approach to the treatment of asthma by the regulation of a novel subset of lymphocytes
Papers (26):
  • Yurie Futoh, Hideyo Miyato, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Kazuya Takahashi, Yuki Kimura, Hiroko Hayakawa, Hideyuki Ohzawa, Naohiro Sata, et al. Effects of vagus nerve signals on the development of peritoneal metastasis of murine gastric cancer. CANCER RESEARCH. 2023. 83. 7
  • Sachie Nakamura, Yasushi Ito, Hiroko Hayakawa, Shiho Aoki, Takanori Yamagata, Hitoshi Osaka. Establishment of a flow cytometry screening method for patients with glucose transporter 1 deficiency syndrome. Molecular Genetics and Metabolism Reports. 2023. 34. 100954-100954
  • Kiyomi Mashima, Kazuya Sato, Takashi Ikeda, Junko Izawa, Norihito Takayama, Hiroko Hayakawa, Shin-Ichiro Kawaguchi, Hirofumi Nakano, Takashi Nagayama, Kento Umino, et al. Dimethyl fumarate ameliorates graft-versus-host disease by inhibiting T-cell metabolism and immune responses through a reactive oxygen species-dependent mechanism. British Journal of Haematology. 2022. 197. 6
  • Rintaro Kuroda, Kaoru Tominaga, Katsumi Kasashima, Kenji Kuroiwa, Eiji Sakashita, Hiroko Hayakawa, Tom Kouki, Nobuhiko Ohno, Kensuke Kawai, Hitoshi Endo. Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo. PLOS ONE. 2021. 16. 7. e0255355-e0255355
  • Morisada Hayakawa, Asuka Sakata, Hiroko Hayakawa, Hikari Matsumoto, Takafumi Hiramoto, Yuji Kashiwakura, Nemekhbayar Baatartsogt, Noriyoshi Fukushima, Yoichi Sakata, Katsue Suzuki-Inoue, et al. Characterization and visualization of murine coagulation factor VIII-producing cells in vivo. Scientific Reports. 2021. 11. 1. 14824-14824
more...
MISC (6):
  • Hirofumi Nakano, Kazuya Sato, Hiroko Hayakawa, Kiyomi Mashima, Daisuke Minakata, Kaoru Morita, Ryoko Yamasaki, Masahiro Ashizawa, Chihiro Yamamoto, Kaoru Hatano, et al. Alloantigen-Activated Human T-Cells Increase Extracellular Fatty Acid Uptake and Intracellular Lipid Metabolism during Xenogeneic Gvhd. Blood. 2018. 132. Supplement 1. 3320-3320
  • Yasufumi Kawasaki, Kazuya Sato, Hiroko Hayakawa, Norihito Takayama, Hirofumi Nakano, Kiyomi Mashima, Daisuke Minakata, Ryoko Yamasaki, Kaoru Morita, Masahiro Ashizawa, et al. Recipient Hematopoietic, but Not Non-Hematopoietic, Antigen-Presenting Cells Are Indispensable for CD4+ T-Cell-Mediated Xenogeneic Graft-Versus-Host Disease. Blood. 2017. 130. 4441
  • Yasufumi Kawasaki, Kazuya Sato, Norihito Takayama, Hiroko Hayakawa, Kiyomi Mashima, Takashi Ikeda, Yumiko Toda, Shoko Ito, Kento Umino, Daisuke Minakata, et al. Comprehensive Analysis of Activation and Proliferation Kinetics and Effector Functions of Human Lymphocyte Subsets in Xenogeneic GvHD Model. BLOOD. 2016. 128. 22
  • Hiroko Hayakawa, Morisada Hayakawa, Hiromi Ohto-Ozaki Shin-ichi Tominaga. Soluble ST2 controls allergic inflammation in a murine model of asthma. FASEB JOURNAL. 2013. 27. S1. 835.4
  • 富永 眞一, 早川 裕子, 早川 盛禎, 柳沢 健. 自然免疫と臨床疾患 ST2遺伝子と病気. 補体シンポジウム講演集. 2008. 45. 89-89
more...
Lectures and oral presentations  (23):
  • Teststerone suppresses allergy-induced airway inflammation in a murine model of Asthma
    (CYTO2019, 34th Congress of the International Society for Advancement of Cytometry 2019)
  • Contribution of type 2 innate lymphoid cells to the gender differences of asthma
    (The 41st Annual Meeting of the Molecular Biology Society of Japan 2018)
  • Relevance of Type 2 Innate Lymphoid Cells in Gender Difference of Asthma
    (CYTO2017, 32nd Congress of the International Society for Advancement of Cytometry 2017)
  • Role of interleukin-33 in acute inflammation
    (2016)
  • Suppression of airway inflammation by binding of soluble ST2 with interleukin-33
    (The 39th Annual Meeting of the Molecular Biology Society of Japan 2016)
more...
Professional career (1):
  • 医学博士 (自治医科大学)
Work history (4):
  • 2011/10 - 現在 自治医科大学 生化学講座 病態生化学部門 客員研究員
  • 2011/04 - 現在 自治医科大学 共同実験機器センター 特殊技能・技術研究支援者
  • 2011/02 - 2011/09 自治医科大学 生化学講座 病態生化学部門 研究生
  • 2010/08 - 2011/01 ハーバード大学・マサチューセッツ総合病院 皮膚科・皮膚科学研究所 テクノロジスト
Awards (2):
  • 2015 - Outstanding Poster Award at CYTO 2015, Outstanding Poster Award at CYTO 2015 Effect of soluble ST2 on activation of type 2 innate lymphoid cells in a murine model of asthma
  • 2008 - * Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation.
Association Membership(s) (3):
International Society for Advancement of Cytometry ,  Japan Cytometry Society ,  The Molecular Biology Society of Japan
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