Rchr
J-GLOBAL ID:202001014023456726   Update date: Aug. 26, 2024

SAKAIRI Hakushun

サカイリ ハクシュン | SAKAIRI Hakushun
Affiliation and department:
Job title: 助教
Homepage URL  (1): http://pharmacology.sakura.ne.jp/jp/research.html
Research field  (5): Pharmacology ,  Pharmacology ,  Pharmacology ,  Pharmacology ,  Pharmacology
Research keywords  (11): 細胞神経科学 ,  神経薬理学 ,  シナプス伝達 ,  GPCR間複合体形成 ,  GPCR間相互作用 ,  アデノシン受容体 ,  GABA B受容体 ,  mGluR ,  代謝型グルタミン酸受容体 ,  GPCR ,  Gタンパク質共役型受容体
Research theme for competitive and other funds  (5):
  • 2022 - 2025 GPCR間相互作用に基づくmGluR1のアミロイドβオリゴマー毒性拮抗作用の解明
  • 2020 - 2022 異種GPCR間の結合を介した新たな小脳運動学習制御機構の解明
  • 2020 - 2021 異種GPCR間相互作用に着目した新たな痒み発症メカニズムの解明
  • 2019 - 2020 GPCR複合体形成に基づく新たな難治性痒みの神経伝達調節メカニズムの解明
  • 2018 - 2019 GPCR複合体形成に基づく新たな難治性痒みの神経伝達調節メカニズムの解明
Papers (4):
  • Yui Kuroda, Miki Nonaka, Yuji Kamikubo, Haruo Ogawa, Takashi Murayama, Nagomi Kurebayashi, Hakushun Sakairi, Kanako Miyano, Akane Komatsu, Tetsushi Dodo, et al. Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomedicine & Pharmacotherapy. 2021. 141. 111800-111800
  • Eriko Komiya, Mitsutoshi Tominaga, Ryo Hatano, Yuji Kamikubo, Sumika Toyama, Hakushun Sakairi, Kotaro Honda, Takumi Itoh, Yayoi Kamata, Munehiro Tsurumachi, et al. Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV. Journal of Allergy and Clinical Immunology. 2021. 149. 3. 1085-1096
  • Hakushun Sakairi, Yuji Kamikubo, Masayoshi Abe, Keisuke Ikeda, Arata Ichiki, Toshihide Tabata, Masanobu Kano, Takashi Sakurai. G Protein-Coupled Glutamate and GABA Receptors Form Complexes and Mutually Modulate Their Signals. ACS chemical neuroscience. 2020. 11. 4. 567-578
  • Yuji Kamikubo, Toshihide Tabata, Hakushun Sakairi, Yoshie Hashimoto, Takashi Sakurai. Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor. Journal of pharmacological sciences. 2015. 128. 3. 125-30
MISC (6):
  • 上窪裕二, 田端俊英, 坂入伯駿, 櫻井隆. 異種G蛋白質共役型受容体相互作用による代謝型グルタミン酸受容体の制御. 脳神経内科. 2021. 第94巻. 4号. 468-475
  • 坂入 伯駿, 上窪 裕二, 田端 俊英. 分子から迫る神経薬理学 GABAB受容体の薬理と臨床応用. Clinical Neuroscience. 2019. 37. 7. 760-761
  • 田端 俊英, 上窪 裕二, 坂入 伯駿. 分子から迫る神経薬理学 GABAB受容体の生理的機能. Clinical Neuroscience. 2019. 37. 6. 630-631
  • 上窪 裕二, 坂入 伯駿, 田端 俊英. 分子から迫る神経薬理学 GABAB受容体の種類と構造. Clinical Neuroscience. 2019. 37. 5. 504-505
  • Sakairi Hakushun, Kamikubo Yuji, Abe Masayoshi, Matsuoka Kenta, Tabata Toshihide, Sakurai Takashi. Metabotropic glutamate receptor 1 (mGluR1) forms hetero-oligomer with other G-protein coupled receptors and they regulate their signal transduction each other at neurons. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2018. 2018. 0. PO1-1-130
more...
Education (2):
  • 2016 - 2020 Juntendo University Graduate School of Medicine
  • 2010 - 2016 Juntendo University Faculty of Medicine
Professional career (1):
  • 博士(医学) (順天堂大学)
Work history (2):
  • 2020/04 - 現在 Juntendo University
  • 2016/04 - 2018/03 順天堂医院 初期研修医
Association Membership(s) (2):
The Japan Neuroscience Society ,  The Japanese Pharmacological Society
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