J-GLOBAL ID:202001014427261660   Update date: Nov. 04, 2020

Komatsu Toshimitsu

コマツ トシミツ | Komatsu Toshimitsu
Affiliation and department:
Job title: 技術職員
Research field  (1): Experimental pathology
Research keywords  (6): anti tumor ,  metabolism ,  Mitochondria ,  FoxOs ,  Aging ,  Calorie restriction
Research theme for competitive and other funds  (7):
  • 2017 - 2019 Functional analysis of inflammation-related microRNA in non-alcoholic steatohepatitis and antisense oligodeoxynucleotide development
  • 2016 - 2019 Analysis the aging mechanisms via WDR6 and aim for building new animal aging model
  • 2016 - 2019 Comprehensive analysis for wound inflammation-related miRNAs and development of novel therapies
  • 2015 - 2019 Regulation of cancer and aging by FoxO and investigation of compounds for regulation of FoxO
  • 2015 - 2018 Establishment of Anti-aging mechanism by NPY in the fat metabolism
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Papers (37):
  • Seongjoon Park, Erkhembayar Nayantai, Toshimitsu Komatsu, Hiroko Hayashi, Ryoichi Mori, Isao Shimokawa. NPY Deficiency Prevents Postmenopausal Adiposity by Augmenting Estradiol-Mediated Browning. The journals of gerontology. Series A, Biological sciences and medical sciences. 2020. 75. 6. 1042-1049
  • Zi Wang, Toshimitsu Komatsu, Yoshihisa Ohata, Yukari Watanabe, Yiwen Yuan, Yuki Yoshii, Seongjoon Park, Ryoichi Mori, Motoyasu Satou, Yoshitaka Kondo, et al. Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. Geriatrics & gerontology international. 2020. 20. 3. 238-247
  • Toshimitsu Komatsu, Seongjoon Park, Hiroko Hayashi, Ryoichi Mori, Haruyoshi Yamaza, Isao Shimokawa. Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction. Nutrients. 2019. 11. 12
  • Maiko de Kerckhove, Katsuya Tanaka, Takahiro Umehara, Momoko Okamoto, Sotaro Kanematsu, Hiroko Hayashi, Hiroki Yano, Soushi Nishiura, Shiho Tooyama, Yutaka Matsubayashi, et al. Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds. EMBO molecular medicine. 2018. 10. 10
  • Katsuya Tanaka, Sang Eun Kim, Hiroki Yano, Gaku Matsumoto, Ryoma Ohuchida, Yuhoko Ishikura, Masatake Araki, Kimi Araki, Seongjoon Park, Toshimitsu Komatsu, et al. MiR-142 Is Required for Staphylococcus aureus Clearance at Skin Wound Sites via Small GTPase-Mediated Regulation of the Neutrophil Actin Cytoskeleton. The Journal of investigative dermatology. 2017. 137. 4. 931-940
Education (2):
  • 2002 - 2006 Nagasaki University
  • 1998 - 2000 Hokkaido University Department of Applied Bioscience
Work history (2):
  • 2000/11 - 現在 Nagasaki University Graduate School of Biomedical Sciences Research engineer
  • 2007/03 - 2009/03 National Institute on Aging Genomics Unit, Laboratory of Experimental Gerontology Visiting Fellow
Awards (2):
  • 2017/06 - 日本老年学会 第30回日本老年学会総会合同ポスター賞 The role of FoxO3a in liver of calorie restriction in mice
  • 2012/06 - 日本抗加齢医学会 第12回日本抗加齢医学会総会優秀演題 カロリー制限の抗腫瘍効果と寿命延長効果におけるFoxO1の役割
Association Membership(s) (2):
日本抗加齢医学会 ,  日本基礎老化学会
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