Rchr
J-GLOBAL ID：202001014480203817   Update date: May. 21, 2024

Matsui Takeshi

マツイ タケシ | Matsui Takeshi
Affiliation and department：
Tokyo University of Technology

About Tokyo University of Technology


Homepage URL  (2)： https://takeshi-matsui-lab.bs.teu.ac.jp ,  https://epithelialevolution.jp/free/english
Research field  (1)： Dermatology
Research keywords  (5)： Adaptive Evolution ,  Protease ,  Endogenous Retrovirus ,  Stratum Corneum ,  Skin
Research theme for competitive and other funds  (13)：
  • 2022 - 2027 Dissecting mechanisms of functional cell death "corneoptosis" and stratum corneum homeostasis regulated by pH and its clinical application
  • 2022 - 2027 Evolutionary origins of the stratum corneum of the skin epidermis based on molecular characterization of water
  • 2016 - 2019 Elucidation for mechanism of dermatitis with model mice which develop dermatitis spontaneously with S.aureus proliferation.
  • 2013 - 2018 Analysis of moisturization mechanism of stratum corneusm
  • 2014 - 2017 The elucidation of the Nagashima-type palmoplantar keratosis caused by SERPINB7 protease inhibitor deficiency
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Papers (49)：
  • Keitaro Fukuda, Yoshihiro Ito, Yuki Furuichi, Takeshi Matsui, Hiroto Horikawa, Takuya Miyano, Takaharu Okada, Mark van Logtestijn, Reiko J. Tanaka, Atsushi Miyawaki, et al. Three stepwise pH progressions in stratum corneum for homeostatic maintenance of the skin. Nature Communications. 2024. 15. 1
  • Hiroyuki Sasaki, Hisako Arai, Emi Kikuchi, Hideki Saito, Keiko Seki, Takeshi Matsui. Novel electron microscopic staining method using traditional dye, hematoxylin. Scientific reports. 2022. 12. 1. 7756-7756
  • Keiichiro Shiraga, Yuichi Ogawa, Shojiro Kikuchi, Masayuki Amagai, Takeshi Matsui. Increase in the Intracellular Bulk Water Content in the Early Phase of Cell Death of Keratinocytes, Corneoptosis, as Revealed by 65 GHz Near-Field CMOS Dielectric Sensor. Molecules. 2022. 27. 9. 2886-2886
  • Hisato Iriki, Hayato Takahashi, Naoko Wada, Hisashi Nomura, Miho Mukai, Aki Kamata, Hiromi Ito, Jun Yamagami, Takeshi Matsui, Yutaka Kurebayashi, et al. Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus. Proceedings of the National Academy of Sciences. 2021. 118. 49
  • Kenji Tago, Satoshi Ohta, Chihiro Aoki-Ohmura, Megumi Funakoshi-Tago, Miho Sashikawa, Takeshi Matsui, Yuki Miyamoto, Taeko Wada, Tomoyuki Oshio, Mayumi Komine, et al. K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors. Scientific Reports. 2021. 11. 1. 20658-20658
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MISC (21)：
  • Hiroyuki Sasaki, Emi Kikuchi, Hideki Saito, Takeshi Matsui. Electron microscopic double staining method with hematoxylin followed by lead citrate. Protocol Exchange. 2022
  • 卜部眞子, 卜部眞子, 白神慧一郎, 松井毅, 菊池正二郎, 小川雄一. 65GHz帯CMOSセンサを用いたアルブミン熱変性に伴う水和数の高精度評価. シンポジウムテラヘルツ科学の最先端講演要旨集. 2019. 2019
  • 菊池 正二郎, 澤田 美香, 鈴木 哲仁, 白神 慧一郎, 小川 雄一, 松井 毅, 篠原 尚. テラヘルツ半導体アレイセンサによる非標識がん細胞計測法の開発. 日本癌学会総会記事. 2017. 76回. P-2319
  • Takeshi Matsui. Adaptive Evolution of Skin in Terrestrial Vertebrates and Possible Involvement of Endogenous Retroviruses. Uirusu. 2016. 66. 1. 31-38
  • Takeshi Matsui, Masayuki Amagai. Dissecting the formation, structure and barrier function of the stratum corneum. International immunology. 2015. 27. 6. 269-80
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Lectures and oral presentations  (10)：
  • Corneoptosis, functional keratinocyte cell death, is tightly associated with spaciotemporal dynamics of epidermal tight junctions. Society for Investigative Dermatology
    (SID 2022 Annual Meeting 2022)
  • 皮膚表皮バリア形成機構の形態学的動態解析
    (第21回Bio電顕セミナー 2022)
  • A unique mode of functional keratinocyte death, corneoptosis requires intracellular acidification
    (2021)
  • Dissecting the epidermal barrier function and its evolution
    (2021)
  • 皮膚表皮顆粒層細胞が起こす細胞死における、細胞内酸性化とレトロウイルス型プロテアーゼの活性化
    (第23回 日本レトロウイルス研究会 夏期セミナー 2021)
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Education (3)：
  • 1996 - 2000 Kyoto University Faculty of Medicine
  • 1994 - 1996 Nara Institute of Science and Technology Graduate School of Biological Sciences
  • 1990 - 1994 Tohoku University Faculty of Agriculture
Professional career (1)：
  • 医学博士 (京都大学大学院医学研究科)
Work history (9)：
  • 2021/04 - 現在 Tokyo University of Technology
  • 2016/09 - 2021/03 RIKEN Center for Integrative Medical Sciences (IMS) Laboratory for Skin Homeostasis Deputy Team Leader
  • 2013/04 - 2016/08 RIKEN Center for Integrative Medical Sciences (IMS) Laboratory for Skin Homeostasis Senior Research Scientist
  • 2011/04 - 2013/03 京都大学 物質-細胞統合システム拠点 柊研究室 特定拠点助教
  • 2007/11 - 2011/03 東京医科歯科大学 難治疾患研究所 メディカル・トップ・トラック(MTT)プログラム 特任講師
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Committee career (3)：
  • 2021/12 - 現在 Japanese Society for Investigative Dermatology Board of Director
  • 2011 - 現在 Japanese society of cell biology Councilor
  • 2015 - 2016 Japan Society of Cell Biology Councilor
Association Membership(s) (6)：
Society of Evolutionary studies, Japan ,  Japanese Cancer Association ,  Japanese Society for Investigative Dermatology ,  The Molecular Biology Society of Japan ,  Japan Society for Cell Biology ,  The Japanese Biochemical Society
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