Hiraga Shin-ichiro

ヒラガシンイチロウ | Hiraga Shin-ichiro

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Neuropathology , Rehabilitation science

Research keywords (8)： CNS border-associated macrophages (CAMs) , Ischemic stress , blood-tissue barriers , Astrocyte , Microglia , Neural circuit reorganization , Pain , Cerebral hemorrhage

Research theme for competitive and other funds (7)：

2024 - 2026 Brain Immune Cell-Mediated Neural Circuit Reconstruction after Stroke
2023 - 2024 Spatio-temporal diversity of microglia in central nervous system diseases
2023 - 2024 Spatio-temporal diversity of microglia in central nervous system diseases
2021 - 2024 Astrocyte-dependent mechanism of persistent pathology of central post-stroke pain
2022 - 2023 Pain treatment by functional control of S1-microglia after thalamic hemorrhage

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Papers (13)：

Shin-ichiro Hiraga, Takahiro Masuda. Common principles of macrophage biology in blood-tissue barriers. Clinical and Experimental Neuroimmunology. 2024
Yuko Morita, Takahide Itokazu, Toru Nakanishi, Shin-Ichiro Hiraga, Toshihide Yamashita. A novel aquaporin-4-associated optic neuritis rat model with severe pathological and functional manifestations. Journal of neuroinflammation. 2022. 19. 1
Shin-ichiro Hiraga, Takahide Itokazu, Mariko Nishibe, Toshihide Yamashita. Neuroplasticity related to chronic pain and its modulation by microglia. Inflammation and Regeneration. 2022. 42. 15. 1-10
Mariko Nishibe, Hiroki Toyoda, Shin-Ichiro Hiraga, Toshihide Yamashita, Yu Katsuyama. Synaptic and Genetic Bases of Impaired Motor Learning Associated with Modified Experience-Dependent Cortical Plasticity in Heterozygous Reeler Mutants. Cerebral Cortex. 2022. 32. 3. 504-519
Shin-ichiro Hiraga, Takahide Itokazu, Maki Hoshiko, Hironobu Takaya, Mariko Nishibe, Toshihide Yamashita. Microglial depletion under thalamic hemorrhage ameliorates mechanical allodynia and suppresses aberrant axonal sprouting. JCI insight. 2020. 5. 3. e131801

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MISC (6)：

平賀慎一郎, 肥田朋子. 疼痛の病態生理学の理解のポイント. 理学療法. 2016. 33. 5. 401-408
平賀慎一郎, 肥田朋子, 堀紀代美, 仲田浩規, 中川達貴, KUMCHANTUEK Tewarat, 井関尚一, 尾崎紀之. 不活動に伴う筋機械痛覚過敏と骨格筋ならびに後根神経節におけるNGFの発現変化. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2016. 121st
松沢匠, 平賀慎一郎, 松原崇紀, 大竹晋平, 中川達貴, 中島智将, 肥田朋子. 手動血圧計を使用したマンシェット圧による疼痛評価の有用性. 愛知県理学療法学会誌. 2015. 27
平賀慎一郎, 肥田朋子, 中川達貴, 堀紀代美, 尾崎紀之. 不活動前に行うTreadmill運動は不活動後の筋痛を抑制する. Pain Rehabilitation. 2015. 5. 2
中川達貴, 肥田朋子, 平賀慎一郎, 堀紀代美, 尾崎紀之. 不活動モデルラットにおける機械的痛覚過敏に対するTRPV4の関与. Pain Rehabilitation. 2015. 5. 2

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Lectures and oral presentations (12)：

Reelinは運動学習における大脳皮質地図の可塑性に関わる
(第128回日本解剖学会総会・全国学術集会 2023)
Microglia-regulated neuroplasticity is associated with chronic pain
(Neuroscience and Pain Symposium 2021)
ミクログリア除去は脳卒中後疼痛と感覚野での異所的軸索発芽を抑制する
(第一回脳科学サロン 2020)
Microglial depletion under thalamic hemorrhage ameliorates pain-like behavior and suppresses aberrant axonal sprouting
(2020)
視床出血後の疼痛関連行動と感覚野での異所的軸索発芽におけるミクログリアの役割
(第13回若手研究フォーラム(大阪大学医学系研究フォーラム) 2019)

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Education (1)：

2016 - 2020 Osaka University Department of Molecular Neuroscience, Graduate School of Medicine

Work history (5)：

2024/04 - 現在 Kyushu University Division of Molecular Neuroimmunology, Medical Institute of Bioregulation Assistant Professor
2023/03 - 2024/03 Institute of Neuropathology and Institute for Disease Modeling and Targeted Medicine (IMITATE), Faculty of Medicine, University of Freiburg Neurocenter, Institute of Neuropathology and Institute for Disease Modeling and Targeted Medicine (IMITATE) Guest researcher
2020/08 - 2023/02 Osaka University Department of Neuro-Medical Science, Graduate School of Medicine Specially Appointed Assistant Professor
2020/04 - 2020/07 Osaka University Department of Neuro-Medical Science, Graduate School of Medicine Specially Appointed Researcher
2018/04 - 2020/03 JSPS Research Fellowship for Young Scientists

Awards (1)：

2018/12 - Young Excellent Presentation Award, The Next Generation Brain Winter Symposium 2018

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