Rchr
J-GLOBAL ID：202001014845578530
Update date: Feb. 01, 2024
Hiramatsu Naoki
ヒラマツ ナオキ | Hiramatsu Naoki
Affiliation and department：
Job title：
副院長 兼 消化器内科部長
Research field (1)：
Gastroenterology
Research keywords (1)：
ウイルス肝炎・肝硬変、肝細胞癌、発症機序、診断と治療
Research theme for competitive and other funds (18)：
- 2013 - 2016 The relationship between the efficacy and the prevalence of the mutant virus for the novel anti-viral drugs for hepatitis C
- 2010 - 2012 Development of novel therapy for hepatocellular carcinoma targeting of bone marrow-derived angiogenesis precursor
- 2010 - 2012 Investigation for the mechanisms of immune tolerance against HCV mediated by tryptophan-catalyzing enzyme, IDO
- 2008 - 2010 Analysis of NASH pathophysiology using glycobiological technique
- 2007 - 2009 Developmental research of tailored immune-modulation therapy against refractory chronic hepatitis C.
- 2007 - 2009 Developmental research on dendritic cell-based immunotherapy against chronic hepatitis C and hepatocellular carcinoma
- 2006 - 2007 Molecular regulation of NK cell cytotoxicity fir human hepatocellular carcinoma
- 2006 - 2007 Hepatitis B virus mutations affecting synthesis of relaxed-circular viral DNA : Relation to disease severity
- 2003 - 2007 Regulation of dendritic cell function and cell-based therapy in chronic hepatitis C virus infection
- 2005 - 2006 CTL immuno-monitoring in chronic hepatitis C
- 2005 - 2006 HBV遺伝子導入マウスでの酵素阻害剤誘発変異の解析とテーラーメイド医療への応用
- 2004 - 2006 Establishment of plasmacytoid dendritic cell-based immune therapy against viral hepatitis and hepatocellular carcinoma
- 2002 - 2003 Suppression of hepatocarcinogenesis by activating natural killer T cells
- 2000 - 2001 Therapeutic strategy for hepatocellular carcinoma by dendritic cell-based tumor vaccination
- 1999 - 2000 Therapetic strategy for chronic hepatitis C by inducing apoptosis of hepatocyte infected with hepatitis C virus
- 1999 - 2000 Application of Ninjurin, a novel adhesion molecule, to diagnosis and therapeutics of primary hepatocellular carcinoma
- 1998 - 2000 Analysis of the molecular mechanism of hepatocarcinogenesis in patients with chronic viral diseases and its application for genetic diagnosis of hepatocellular carcinoma.
- 1996 - 1998 Therapeutic approach to hepatitis C using single-chain antibody and DNA gene transfer
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Papers (289)：
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Yuki Tahata, Ryotaro Sakamori, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Hideki Hagiwara, Masahide Oshita, Yasuharu Imai, Naoki Hiramatsu, Eiji Mita, et al. Improved Liver Function After Sustained Virologic Response Enhanced Prognosis in Hepatitis C with Compensated Advanced Liver Fibrosis. Digestive diseases and sciences. 2023. 68. 5. 2115-2122
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Yuki Tahata, Ryotaro Sakamori, Kazuki Maesaka, Akira Doi, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Masanori Miyazaki, Yasutoshi Nozaki, Akira Kaneko, et al. Effect of sofosbuvir and velpatasvir therapy on clinical outcome in hepatitis C virus patients with decompensated cirrhosis. Hepatology research : the official journal of the Japan Society of Hepatology. 2023. 53. 4. 301-311
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Takayuki Matsumae, Takahiro Kodama, Yuki Tahata, Yuta Myojin, Akira Doi, Akira Nishio, Ryoko Yamada, Yasutoshi Nozaki, Masahide Oshita, Naoki Hiramatsu, et al. Thrombospondin-2 as a Predictive Biomarker for Hepatocellular Carcinoma after Hepatitis C Virus Elimination by Direct-Acting Antiviral. Cancers. 2023. 15. 2
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Kazuki Maesaka, Ryotaro Sakamori, Ryoko Yamada, Akira Doi, Yuki Tahata, Kazuyoshi Ohkawa, Masahide Oshita, Masanori Miyazaki, Takayuki Yakushijin, Yasutoshi Nozaki, et al. Pretreatment with antibiotics is associated with reduced therapeutic response to atezolizumab plus bevacizumab in patients with hepatocellular carcinoma. PloS one. 2023. 18. 2. e0281459
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Yuki Tahata, Ryotaro Sakamori, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Yasutoshi Nozaki, Masahide Oshita, Naoki Hiramatsu, Masanori Miyazaki, Eiji Mita, et al. Risk of hepatocellular carcinoma after sustained virologic response in hepatitis C virus patients without advanced liver fibrosis. Hepatology research : the official journal of the Japan Society of Hepatology. 2022. 52. 10. 824-832
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MISC (133)：
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Yuta Myojin, Hayato Hikita, Yuki Tahata, Akira Doi, Seiya Kato, Yoichi Sasaki, Kumiko Shirai, Sadatsugu Sakane, Ryoko Yamada, Takahiro Kodama, et al. Letter: serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination-authors' reply. Alimentary pharmacology & therapeutics. 2022. 55. 8. 1061-1062
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Ayako Urabe, Ryotaro Sakamori, Tomohide Tatsumi, Ryoko Yamada, Yuki Tahata, Yasuharu Imai, Akira Yamada, Naoki Hiramatsu, Hideki Hagiwara, Masahide Oshita, et al. Effects of IFN-free therapy for hepatitis C virus after hepatocellular carcinoma treatment on early HCC recurrence compared to IFN-based therapy. HEPATOLOGY. 2017. 66. 843A-844A
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Ryoko Yamada, Ryotaro Sakamori, Tomohide Tatsumi, Takayuki Yakushijin, Tsugiko Oze, Ayako Urabe, Yuki Tahata, Naoki Morishita, Atsushi Housui, Sadaharu Lio, et al. Risk factors for liver cancer in chronic hepatitis C are different between the early and late periods after sustained virological response. HEPATOLOGY. 2016. 64. 642A-643A
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Atsuo Takigawa, Ryotaro Sakamori, Tomohide Tatsumi, Tadashi Kegasawa, Kunimaro Furuta, Hayato Hikita, Takayuki Yakushijin, Ichiyo Itose, Hideki Hagiwara, Atsushi Hosui, et al. The prognostic factors after initial RFA for primary hepatocellular carcinoma. HEPATOLOGY. 2016. 64. 647A-647A
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Ayako Urabe, Ryotaro Sakamori, Tomohide Tatsumi, Takayuki Yakushijin, Ryoko Yamada, Tsugiko Oze, Naoki Morishita, Yuki Tahata, Atsushi Hosui, Takuya Miyagi, et al. Efficacy and safety of sofosbuvir-based therapy for aged patients with chronic hepatitis C. HEPATOLOGY. 2016. 64. 996A-997A
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Books (3)：
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肝炎どう診る?どう治す?
医事新報社 2020
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はじめての消化器内視鏡看護
メディカ出版 2019 ISBN:9784840469258
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必ず役立つ!肝炎診療バイブル : 研修医・レジデント必携 : 各種ガイドライン準拠 = The bible of treatment for hepatitis
メディカ出版 2018 ISBN:9784840465267
Education (1)：
Association Membership(s) (1)：
日本肝臓学会、日本消化器病学会、日本内視鏡学会、日本膵臓学会、米国肝臓学会、欧州肝臓学会
