Rchr
J-GLOBAL ID：202001015594436397
Update date: May. 07, 2024
NAKAMICHI Kazuo
ナカミチ カズオ | NAKAMICHI Kazuo
Affiliation and department：
Job title：
Senior Investigator
Research field (2)：
Neurology
, Virology
Research keywords (8)：
Clinical Virology
, Epidemiology
, Neuroinfection
, Progressive multifocal leukoencephalopathy
, Polyomavirus
, JC virus
, Laboratory diagnosis
, Mutation analysis
Research theme for competitive and other funds (13)：
- 2023 - 2026 Research Committee of Prion Disease and Slow Virus Infection
- 2021 - 2024 進行性多巣性白質脳症を引き起こすJCウイルスの再活性化機序の解析と評価系の構築
- 2021 - 2023 Research Committee of Prion Disease and Slow Virus Infection
- 2018 - 2021 Progressive multifocal leukoencephalopathy (PML); Analysis of anti-JC viral reaction and host immune response
- 2017 - 2020 Development of ultra-sensitive PCR testing technology for a wide range of neuroinfections including progressive multifocal leukoencephalopathy
- 2014 - 2017 Analysis of mutational mechanism of JC virus in patients with progressive multifocal leukoencephalopathy during mefloquine administration
- 2012 - 2015 HIV陽性者における進行性多巣性白質脳症に対する高精度検査技術の開発および診断への応用
- 2010 - 2012 Identification and application of human brain genes that facilitate JC virus replication.
- 2007 - 2009 Molecular analysis of virus-induced chemokine production in brain glial cells.
- 2004 - 2007 Toll様受容体(TLR3)を介したミクログリア活性化機序の解明と脳炎治療薬開発のためのハイスループット試験系への応用
- 2004 - 2006 中枢神経系ウイルスがミクログリア特異的なケモカイン発現を誘導するメカニズムの解明
- 2004 - 2005 新規脳疾患治療薬スタチンがミクログリアの活性化シグナリングを抑制する分子メカニズム
- 2001 - 2001 ウシヘルペスウイルス1型(BHV-1)の糖タンパク質gGの機能解析
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Papers (101)：
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Sachiko Hasebe, Kota Maekawa, Yukiko Shishido-Hara, Kazuo Nakamichi, Nobuaki Funata, Makio Takahashi. Inflammatory progressive multifocal leukoencephalopathy with human T-cell lymphotropic virus-1 coinfection. BMJ Case Reports. 2024. 17. 4
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Hidetada Yamada, Megumi Toko, Masahiro Nakamori, Hiroki Ueno, Shiro Aoki, Tomohiro Sugimoto, Hiroko Yasutomi, Kazuo Nakamichi, Hirofumi Maruyama. Progressive multifocal leukoencephalopathy associated with systemic lupus erythematosus: longitudinal observation of lymphocytes, JC virus in cerebrospinal fluid, and brain magnetic resonance imaging. Journal of Neurovirology. 2024
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Mami Matsuda, Tian-Cheng Li, Akira Nakanishi, Kazuo Nakamichi, Makoto Saito, Tadaki Suzuki, Tomokazu Matsuura, Masamichi Muramatsu, Tetsuro Suzuki, Yoshiharu Miura, et al. Generation of JC Polyoma Pseudovirus for High-Throughput Measurement of Neutralizing Antibodies. Diagnostics. 2024. 14. 3
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Yuta Chiba, Rie Kawakita, Katsuya Mitamura, Kenta Takahashi, Tadaki Suzuki, Kazuo Nakamichi, Kenta Suzuki, Asahiro Morishita, Hideki Kobara, Kazushi Deguchi, et al. 18F-THK5351 Positron Emission Tomography Clearly Depicted Progressive Multifocal Leukoencephalopathy After Mantle Cell Lymphoma Treatment. Internal Medicine. 2024
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Neri Sone, Hiroki Nishiwaki, Mayu Shimokawa, Keishu Kawanishi, Tsuyoshi Oshiro, Reiji Takami, Natsuki Taira, Masahito Amagasa, Shinya Omiya, Tadahide Maezumi, et al. A case of progressive multifocal leukoencephalopathy in a post-kidney transplant patient with improvement after discontinuation of immunosuppressive drugs and combination therapy with mefloquine and mirtazapine. Renal Replacement Therapy. 2023. 9. 1. 62
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MISC (148)：
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田中 裕彬, 七浦 仁紀, 安東 孝記, 山岡 美奈子, 桐山 敬生, 形岡 博史, 中道 一生, 杉江 和馬. 多発性骨髄腫に対するポマリドミド投与中に発症した小脳・脳幹型進行性多巣性白質脳症の一例. 臨床神経学. 2023. 63. 10. 688-688
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三浦 義治, 齊藤 誠, 石橋 小百合, 渡邉 玲, 河合 芙由子, 奥山 美樹, 松田 隼弥, 銭谷 怜史, 中道 一生, 横手 裕明. 本邦発症進行性多巣性白質脳症(PML)患者のHLAの解析. 神経免疫学. 2023. 28. 1. 216-216
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臼井 宏二郎, 北崎 佑樹, 榎本 崇一, 森田 美穂子, 中道 一生, 濱野 忠則. 多発性骨髄腫に対するダラツムマブ,ボルテゾミブ,デキサメタゾン投与中に進行性多巣性白質脳症を発症した1例. 臨床神経学. 2023. 63. 8. 513-517
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中道 一生. 「明日の実地臨床から使える神経感染症の検査法とその解釈」 進行性多巣性白質脳症の臨床と検査. NEUROINFECTION. 2023. 28. 1. 22-26
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鈴木 有紀, 阪田 良一, 村上 丈伸, 瀧川 洋史, 牧島 かれん, 足立 正, 高橋 健太, 中道 一生, 三浦 義治, 花島 律子. オビヌツズマブ・ベンダムスチン(GB)療法後にリング状造影増強効果を伴う病変を呈した進行性多巣性白質脳症(PML)の一例. 臨床神経学. 2023. 63. 5. 323-323
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Education (1)：
- 2000 - 2002 Graduate School of Agricultural and Life Sciences, The University of Tokyo
Professional career (2)：
- Ph.D. (The University of Tokyo)
- M.S. (The University of Tokyo)
Work history (3)：
- 2007 - 現在 National Institute of Infectious Diseases Department of Virology 1 Senior Investigator
- 2003 - 2006 National Institute of Infectious Diseases Department of Virology 1 Research Scientist
- 2001 - 2002 Japan Society for the Promotion of Science Research Fellow
Committee career (2)：
- 2014/09 - 現在 Japanese Society for Neuroinfectious Diseases Councilor
- 2014/09 - 現在 Japanese Society for Neuroinfectious Diseases Editorial board member
Association Membership(s) (2)：
Japanese Society for Neuroinfectious Diseases
, The Japanese Society for Virology
