Rchr
J-GLOBAL ID：202001015917092161
Update date: Nov. 11, 2024
Hanaki Yusuke
Hanaki Yusuke
Affiliation and department：
Research field (3)：
Bioorganic chemistry
, Environmental and pharmaceutical development resources
, Pharmaceuticals - chemistry and drug development
Research keywords (3)：
Medicinal Chemistry
, Bioregulation Chemistry
, Structure Activity Relationship
Research theme for competitive and other funds (7)：
Papers (20)：
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Ryo C. Yanagita, Yoshiyuki Suzuki, Yasuhiro Kawanami, Yusuke Hanaki, Kazuhiro Irie. Effect of phenolic-hydroxy-group incorporation on the biological activity of a simplified aplysiatoxin analog with an (R)-(-)-carvone-based core. Bioscience, Biotechnology, and Biochemistry. 2024. 88. 9. 992-998
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Yusuke Hanaki, Rintaro Abe, Yasunori Sugiyama, Yasumasa Hara, Ryo C. Yanagita. A new labdane-type diterpenoid from leaves of <i>Vitex rotundifolia<i/>. Results in Chemistry. 2024. 7. 101512
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Jumpei Maki, Yusuke Hanaki, Ryo C. Yanagita, Masayuki Kikumori, Anastasiia Kovba, Ayaka Washizaki, Chihiro Tsukano, Hirofumi Akari, Kazuhiro Irie. Biological evaluation of a phosphate ester prodrug of 10-methyl-aplog-1, a simplified analogue of aplysiatoxin, as a possible latency-reversing agent for HIV reactivation. Bioscience, Biotechnology, and Biochemistry. 2023. 87. 12. 1453-1461
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Yusuke Hanaki, Yuki Shikata, Masayuki Kikumori, Mutsumi Okamura, Shingo Dan, Masaya Imoto, Kazuhiro Irie. In vivo anti-cancer activity of 10-methyl-aplog-1, a simplified analog of aplysiatoxin, and its possible signaling pathway associated with G1 arrest. Biochemical and Biophysical Research Communications. 2023. 675. 19-25
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Yusuke Hanaki, Nichika Iwase, Yasunori Sugiyama, Sena Miyoshi, Ryo C. Yanagita. Cell morphology-based screening identified vitetrifolin D from Vitex rotundifolia as an inhibitor of phorbol ester-induced downregulation of E-cadherin in HHUA endometrial cells. BPB Reports. 2023. 6. 3. 103-107
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Lectures and oral presentations (55)：
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希少8・9炭糖合成を触媒するトランスアルドラーゼのX線結晶解析
(第97回日本生化学会大会 2024)
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新規 Vibsanin A 誘導体の合成と生物活性の評価
(日本農芸化学会2024年度中四国支部大会(第69回講演会) 2024)
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Pseudomonas cichorii ST-24 由来 D-タガトース-3-エピメラーゼを用いたケトヘプトー スのエピ化反応
(日本農芸化学会2024年度中四国支部大会(第69回講演会) 2024)
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線維環境下での細胞応答に着目した創薬シーズの探索および合成
(日本農芸化学会2024年度中四国支部大会(第69回講演会)2024年度日本農芸化学会中四国支部奨励賞受賞講演 2024)
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婦人科疾患治療薬シーズの開発を指向した天然物研究
(日本農芸化学会中四国支部第39回若手研究者シンポジウム 2024)
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Education (4)：
- 2015 - 2018 Kyoto University Graduate School of Agriculture
- 2012 - 2014 Kyoto University Graduate School of Agriculture
- 2008 - 2012 Kyoto University Faculty of Agriculture
- 2004 - 2007 愛知県立旭丘高等学校 普通科
Professional career (1)：
Work history (5)：
- 2020/10 - 現在 Kagawa University Faculty of Agriculture Department of Applied Biological Science Assistant Professor
- 2019/10 - 2020/09 Scripps Research Postdoctoral Fellow
- 2018/04 - 2020/09 Nagoya University Research Fellow (PD) of The Japan Society for the Promotion of Science (JSPS)
- 2016/04 - 2018/03 Kyoto University Research Fellow (DC2) of The Japan Society for the Promotion of Science (JSPS)
- 2014/04 - 2015/03 DKS Co. Ltd. Researcher
Awards (2)：
- 2024/09 - 日本農芸化学会中四国支部 2024年度 日本農芸化学会中四国支部奨励賞 線維環境下での細胞応答に着目した創薬シーズの探索および合成
- 2019/03 - 2019年度日本農芸化学会大会 優秀発表(ポスター発表選出) Oscillatoxin Dの全合成と生物活性評価
Association Membership(s) (2)：
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY
, JAPAN SOCIETY FOR BIOSCIENCE
