Rchr
J-GLOBAL ID:202001016208654179
Update date: Apr. 24, 2024
ISHIHARA Naotada
イシハラ ナオタダ | ISHIHARA Naotada
Affiliation and department:
Job title:
Professor
Homepage URL (2):
https://mitochondria.jp/
,
https://mitochondria.jp/englishpage
Research field (3):
Functional biochemistry
, Cell biology
, Morphology, anatomy
Research keywords (4):
membrane protein
, cell biology
, mitochondria
, dynamics of organelle membrane
Research theme for competitive and other funds (13):
- 2016 - 2022 筋萎縮の病態に迫るミトコンドリアのメカノバイオロジー
- 2017 - 2020 Cooperative regulation of mitochondrial membrane and genome in mammalian cells
- 2018 - ミトコンドリアの経年劣化による個体機能低下の分子基盤
- 2016 - 2018 病変型mtDNAの選別・浄化におけるマイトファジー関連膜動態の役割
- 2014 - 2018 Regulation and physiological role of mitochondrial fusion and fission in mammals
- 2014 - 2016 ミトコンドリア品質管理における融合・分裂の役割の再検討
- 2010 - 2010 ミトコンドリアネットワークを制御するGTPase群の分子機構
- 2010 - 2010 哺乳動物ミトコンドリアの融合・分裂の分子機構とその生理機能
- 2008 - 2009 融合と分裂によるミトコンドリアネットワーク制御の分子機構の解析
- 2008 - 2009 Physiological roles of mitochondrial fission factor Drp1 in mammal.
- 2005 - 2006 ミトコンドリア融合を制御するGTPase・MitofusinとOPA1の機能解析
- 2003 - 2004 動物細胞ミトコンドリア融合を調節するGTPase・FZOの機能解析
- 2001 - 2002 動物細胞ミトコンドリアの形態形成因子FZOの機能解析
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Papers (71):
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Haruna Harada, Koko Moriya, Hirotsugu Kobuchi, Naotada Ishihara, Toshihiko Utsumi. Protein N-myristoylation plays a critical role in the mitochondrial localization of human mitochondrial complex I accessory subunit NDUFB7. Scientific Reports. 2023. 13. 1
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Kaori Hozumi, Kenji Sugawara, Takaya Ishihara, Naotada Ishihara, Wataru Ogawa. Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes. Scientific Reports. 2023. 13. 1. 746-746
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Tatsuki Yasuda, Takaya Ishihara, Ayaka Ichimura, Naotada Ishihara. Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways. Cell Reports. 2023. 42. 5. 112434-112434
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Yuichi Abe, Ronald J.A. Wanders, Hans R. Waterham, Hanna Mandel, Tzipora C. Falik-Zaccai, Naotada Ishihara, Yukio Fujiki. Genetic defects in peroxisome morphogenesis (Pex11β, dynamin-like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid-phospholipid metabolism. Journal of Inherited Metabolic Disease. 2023. 46. 2. 273-285
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Takaya Ishihara, Reiko Ban-Ishihara, Azusa Ota, Naotada Ishihara. Mitochondrial nucleoid trafficking regulated by the inner-membrane AAA-ATPase ATAD3A modulates respiratory complex formation. Proceedings of the National Academy of Sciences. 2022. 119. 47
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MISC (39):
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石原 孝也, 石原 玲子, 石原 直忠. ミトコンドリアゲノムの新しい制御機構 核様体のダイナミクスとその意義. 生化学. 2023. 95. 5. 650-654
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市川葵, 石原孝也, 石原直忠. ミトコンドリアの膜とDNAのダイナミクスとその制御機構. 実験医学増刊. 2023. 41. 5. 651-656
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山本正道, 石原直忠. ミトコンドリア研究の最前線と新潮流 ~代謝制御のキープレイヤーの動的なふるまいと創薬への展開~. 生化学. 2022. 94. 2. 157-158
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花田 有希, 石原 孝也, 石原 直忠. 代謝と自然免疫をつなぐミトコンドリアの細胞情報伝達機構. 生化学. 2022. 94. 2. 230-235
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石原孝也, 前田真希, 石原直忠. ミトコンドリアダイナミクスと疾病研究 ~多彩な機能と形態を大きく変動させるミトコンドリア~. ミトコンドリアダイナミクス 株式会社エヌ・ティー・エス. 2021
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Education (3):
- 1995 - 1998 Kyushu University Graduate School of Medical Science Department of Molecular Biology
- 1993 - 1995 Kyushu University Graduate School of Science Department of Biology
- 1989 - 1993 Kyushu University School of Sciences Department of Biology
Work history (6):
- 2018 - 現在 Osaka University, Department of Biological Sciences, Graduate School of Science, Professor
- 2019 - 2023 Japanese Society of Mitochondrial Research and Medicine (J-mit), President
- 2010 - 2018 Kurume University, Institute of Life Science, Professor
- 2007 - 2010 Tokyo Medical and Dental University, Graduate School and Faculty of Medicine, Research Assistant Professor / Junior Associate Professor
- 2000 - 2006 Kyushu University, Graduate School of Medical Science, Research Assistant Professor
- 1998 - 2000 National Institute for Basic Biology, Postdoctoral fellow
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Awards (2):
- 2010 - The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, Japan Award for The Young Scientists’ Prize
- 2009 - The Japanese Biochemical Society Young Investigator Award
Association Membership(s) (4):
日本ミトコンドリア学会
, 日本分子生物学会
, 日本細胞生物学会
, 日本生化学会
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