ISHIHARA Naotada

イシハラナオタダ | ISHIHARA Naotada

Affiliation and department：
Job title： Professor
Homepage URL (2)： https://mitochondria.jp/ , https://mitochondria.jp/englishpage

Research field (3)： Functional biochemistry , Cell biology , Morphology, anatomy

Research keywords (4)： membrane protein , cell biology , mitochondria , dynamics of organelle membrane

Research theme for competitive and other funds (16)：

2024 - 2029 ミトコンドリア介入による生体機能亢進技術の構築
2024 - 2029 Genomic regulation of intracellular symbiotic organelles: from technological innovation to understanding and application of life phenomena
2024 - 2027 ミトコンドリアDNAの動態とヘテロプラスミー制御の分子基盤の解明
2018 - 2024 ミトコンドリアの経年劣化による個体機能低下の分子基盤
2016 - 2022 筋萎縮の病態に迫るミトコンドリアのメカノバイオロジー

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Papers (73)：

Yuki Hanada, Risa Maeda, Takaya Ishihara, Masaki Nakahashi, Yuichi Matsushima, Emi Ogasawara, Toshihiko Oka, Naotada Ishihara. Alternative splicing of Mff regulates AMPK-mediated phosphorylation, mitochondrial fission and antiviral response. Pharmacological Research. 2024
Chang Lin Chen, Takaya Ishihara, Soumyadip Pal, Wei Ling Huang, Emi Ogasawara, Chuang Rung Chang, Naotada Ishihara. SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies. Mitochondrion. 2024. 79
Haruna Harada, Koko Moriya, Hirotsugu Kobuchi, Naotada Ishihara, Toshihiko Utsumi. Protein N-myristoylation plays a critical role in the mitochondrial localization of human mitochondrial complex I accessory subunit NDUFB7. Scientific Reports. 2023. 13. 1
Kaori Hozumi, Kenji Sugawara, Takaya Ishihara, Naotada Ishihara, Wataru Ogawa. Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes. Scientific Reports. 2023. 13. 1. 746-746
Tatsuki Yasuda, Takaya Ishihara, Ayaka Ichimura, Naotada Ishihara. Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways. Cell Reports. 2023. 42. 5. 112434-112434

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MISC (42)：

パルソモディップ, 石原直忠. 動的ミトコンドリアが担う個体機能:複雑な形態制御と分子レベルからの洞察. 週刊医学のあゆみ (in press). 2024. 291. 6. 250403-250408
小笠原絵美, 前田真希, 石原直忠. ミトコンドリアの多彩な機能と動的な構造変化. 実験医学別冊 (in press). 2024
小笠原絵美, 林里美, 石原直忠. ミトコンドリアの古くて新しい謎:ミトコンドリアDNAの動的特性の理解を目指して. 基礎老化研究 (in press). 2024. 48. 3. 3-5
石原孝也, 石原玲子, 石原直忠. ミトコンドリアゲノムの新しい制御機構核様体のダイナミクスとその意義. 生化学. 2023. 95. 5. 650-654
市川葵, 石原孝也, 石原直忠. ミトコンドリアの膜とDNAのダイナミクスとその制御機構. 実験医学増刊. 2023. 41. 5. 651-656

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Education (3)：

1995 - 1998 Kyushu University Graduate School of Medical Science Department of Molecular Biology
1993 - 1995 Kyushu University Graduate School of Science Department of Biology
1989 - 1993 Kyushu University School of Sciences Department of Biology

Work history (6)：

2018 - 現在 Osaka University, Department of Biological Sciences, Graduate School of Science, Professor
2019 - 2023 Japanese Society of Mitochondrial Research and Medicine (J-mit), President
2010 - 2018 Kurume University, Institute of Life Science, Professor
2007 - 2010 Tokyo Medical and Dental University, Graduate School and Faculty of Medicine, Research Assistant Professor / Junior Associate Professor
2000 - 2006 Kyushu University, Graduate School of Medical Science, Research Assistant Professor

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Awards (2)：

2010 - The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, Japan Award for The Young Scientists’ Prize
2009 - The Japanese Biochemical Society Young Investigator Award

Association Membership(s) (4)：

日本ミトコンドリア学会 , 日本分子生物学会 , 日本細胞生物学会 , 日本生化学会

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