KAKINO Akemi

カキノアケミ | KAKINO Akemi

Affiliation and department：

Research field (2)： Pathobiochemistry , Pharmacology

Research theme for competitive and other funds (9)：

2023 - 2026 骨格筋の新機能としての老廃物除去機能を解明する
2021 - 2024 肺高血圧症病態生理における血管内皮機能分子の意義の解明
2019 - 2023 The risk assessment of coronary artery diseas by a novel method to measure dysfunctional HDL-C
2018 - 2022 Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.
2018 - 2021 Elucidation of the mechanism of cerebral infarction using genome-edited rats

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Papers (38)：

Cong Thanh Nguyen, Misako Nakayama, Hirohito Ishigaki, Yoshinori Kitagawa, Akemi Kakino, Marumi Ohno, Masashi Shingai, Yasuhiko Suzuki, Tatsuya Sawamura, Hiroshi Kida, et al. Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaque. Virology. 2024. 110052-110052
Kento Hosomi, Hidekazu Kawashima, Atsushi Nakano, Akemi Kakino, Yuko Okamatsu-Ogura, Yuki Yamashita, Mai Sasaoka, Daisaku Masuda, Shizuya Yamashita, Chu-Huang Chen, et al. NanoSPECT imaging reveals the uptake of 123I-labelled oxidized low-density lipoprotein in the brown adipose tissue of mice via CD36. Cardiovascular research. 2023. 119. 4. 1008-1020
Marumi Ohno, Michihito Sasaki, Yasuko Orba, Toshiki Sekiya, Md. Abdul Masum, Osamu Ichii, Tatsuya Sawamura, Akemi Kakino, Yasuhiko Suzuki, Hiroshi Kida, et al. Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 2. Viruses. 2021. 13. 11. 2137-2137
Mizuki Sata, Akemi Kakino, Aya Hirata, Miho Iida, Yoko Usami, Sei Harada, Yoshiko Fujita, Shun Kohsaka, Yoshikane Izawa, Mitsuaki Sawano, et al. Serum modified high-density lipoprotein and risk of atherosclerotic cardiovascular disease in a Japanese community-based nested case-control study. European Journal of Preventive Cardiology. 2021
Marumi Ohno, Akemi Kakino, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Tatsuya Sawamura, Hiroshi Kida. Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model. Scientific Reports. 2021. 11. 1

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MISC (6)：

垣野明美, 沢村達也. 研究者の最新動向ヒト変性LDLによる心血管病リスク層別化とその生体での機能. Precision Medicine. 2018. 1. 1. 120-124
山本浩一, 濱野剛, 黄一淋, 垣野明美, 沢村達也, 楽木宏実. アンジオテンシンII(AII)1型受容体(AT1)のアロステリックな活性化による酸化LDLの新規細胞内取り込み機構の解明. 日本高血圧学会総会プログラム・抄録集. 2018. 41回. OB05-02
横田千晶, 沢村達也, 渡邊至, 小久保喜弘, 藤田佳子, 垣野明美, 中井陸運, 豊田一則, 宮本恵宏, 峰松一夫. 脳出血とアテローム血栓性脳梗塞における可溶性Lectin-like oxidized LDL receptor-1高値症例・対照研究. 脳循環代謝. 2015. 27. 1. 165-165
垣野明美, 沢村達也. 【動脈硬化予防の新たなバイオマーカー】変性LDLとsLOX-1のバイオマーカーとしての意義. 動脈硬化予防. 2015. 14. 1. 40-45
S. Ogura, T. Shimosawa, S. Mu, F. Mori, H. Wang, Y. Uetake, Y. Sato, Y. Fujita, A. Kakino, S. Iwamoto, et al. Lectin-Like Oxidized LDL Receptor-1 And Vascular Injury By Rac1 Acitvation Under Chronic Hypoxia. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2009. 137. S150-S150

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