Tokuda Shinsaku

トクダシンサク | Tokuda Shinsaku

Research theme for competitive and other funds (1)：

2023 - 2026 Elucidation of drug resistance by the hypoxic environment adaptation mechanism in lung cancer and development of novel therapeutic strategy

Papers (5)：

Kenji Morimoto, Tadaaki Yamada, Soichi Hirai, Yuki Katayama, Sarina Fukui, Ryo Sawada, Yusuke Tachibana, Yohei Matsui, Ryota Nakamura, Masaki Ishida, et al. AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells. Cancer letters. 2024. 216692-216692
Shota Takei, Hayato Kawachi, Tadaaki Yamada, Motohiro Tamiya, Yoshiki Negi, Yasuhiro Goto, Akira Nakao, Shinsuke Shiotsu, Keiko Tanimura, Takayuki Takeda, et al. Prognostic impact of clinical factors for immune checkpoint inhibitor with or without chemotherapy in older patients with non-small cell lung cancer and PD-L1 TPS ≥ 50. Frontiers in immunology. 2024. 15. 1348034-1348034
Soichi Hirai, Tadaaki Yamada, Yuki Katayama, Masaki Ishida, Hayato Kawachi, Yohei Matsui, Ryota Nakamura, Kenji Morimoto, Mano Horinaka, Toshiyuki Sakai, et al. Effects of Combined Therapeutic Targeting of AXL and ATR on Pleural Mesothelioma Cells. Molecular cancer therapeutics. 2023
Kenji Morimoto, Tadaaki Yamada, Takayuki Takeda, Shinsuke Shiotsu, Koji Date, Taishi Harada, Nobuyo Tamiya, Yusuke Chihara, Osamu Hiranuma, Takahiro Yamada, et al. Efficacy and Safety of Programmed Death-Ligand 1 Inhibitor Plus Platinum-Etoposide Chemotherapy in Patients With Extensive-Stage SCLC: A Prospective Observational Study. JTO clinical and research reports. 2022. 3. 7. 100353-100353
Keiko Tanimura, Tadaaki Yamada, Mano Horinaka, Yuki Katayama, Sarina Fukui, Kenji Morimoto, Takayuki Nakano, Shinsaku Tokuda, Yoshie Morimoto, Masahiro Iwasaku, et al. Inhibition of c-Jun N-terminal kinase signaling increased apoptosis and prevented the emergence of ALK-TKI-tolerant cells in ALK-rearranged non-small cell lung cancer. Cancer letters. 2021. 522. 119-128

Professional career (1)：

医学博士 (神戸大学大学院医学研究科)

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