Rchr
J-GLOBAL ID:202001017080821146
Update date: Apr. 24, 2024
Nishikawa Masashi
ニシカワ マサシ | Nishikawa Masashi
Affiliation and department:
Job title:
Assistant professor
Homepage URL (2):
https://www.bio.nagoya-u.ac.jp/laboratory/cr.html
,
https://www.bio.nagoya-u.ac.jp/english/laboratory/cr.html
Research field (5):
Developmental biology
, Neuroanatomy and physiology
, Neuroscience - general
, Cell biology
, Molecular biology
Research keywords (7):
Molecular biology
, In utero electroporation
, G protein
, Neurodevelopmental disorders
, cytoskeleton
, Neurodevelopment
, cell signaling pathway
Research theme for competitive and other funds (7):
- 2022 - 2027 大脳発達における知的障害責任分子 Rac1の生理機能と分子病態機構の解明
- 2023 - 2025 Cdc42異常に基づく小頭症・脳皮質形成異常症を伴う知的障害の病態メカニズム解析
- 2023 - 2025 知的障害責任分子RhoGの神経発達障害メカニズムの解明
- 2022 - 2023 J-RDMMモデル生物プロジェクト
- 2021 - 2023 知的障害責任分子Rac3の大脳発達における生理機能と分子病態機構の解明
- 2020 - 2022 Pathophysiological analyses of PLEKHG2, a responsible gene for neurodevelopmental disorders, during corticogenesis
- 2018 - 2020 新規GPCRシグナル依存性Rho活性化因子の同定と細胞形態制御機構の解明
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Papers (23):
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Masashi Nishikawa, Koh-ichi Nagata, Hidenori Tabata. Live Imaging of Migrating Neurons and Glial Progenitors Visualized by in Utero Electroporation. Methods in Molecular Biology. 2024. 201-209
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西川将司. Rac シグナルの破綻による神経発達障害発症機構の解明. 神経化学. 2023
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Yumi Tsuneura, Taeko Kawai, Keitaro Yamada, Shintaro Aoki, Mitsuko Nakashima, Shima Eda, Tohru Matsuki, Masashi Nishikawa, Koh-ichi Nagata, Yasushi Enokido, et al. A Novel Constitutively Active c:98G > C, p.(R33P) Variant in RAB11A Associated with Intellectual Disability Promotes Neuritogenesis and Affects Oligodendroglial Arborization. Human Mutation. 2023. 2023. 1-12
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Masashi Nishikawa, Tohru Matsuki, Nanako Hamada, Atsuo Nakayama, Hidenori Ito, Koh-ichi Nagata. Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development. Medical Molecular Morphology. 2023
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Rie Seyama, Masashi Nishikawa, Yuri Uchiyama, Keisuke Hamada, Yuka Yamamoto, Masahiro Takeda, Takanori Ochi, Monami Kishi, Toshifumi Suzuki, Kohei Hamanaka, et al. A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association. Scientific Reports. 2023. 13. 1
more...
MISC (1):
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小林 知世, 西川 将司, 中野 駿, 石川 奈津子, 大脇 千智, 杉山 剛志, 山川 央, 長瀬 隆弘, 上田 浩. FYNによるRho活性化因子PLEKHG1の活性制御機構. 生命科学系学会合同年次大会. 2017. 2017年度. [3P-0428]
Lectures and oral presentations (25):
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Rac-グアニンヌクレオチド交換因子 Prex1 の神経発達における生理機能
(第64回日本神経病理学会総会学術研究会/ 第66回日本神経化学会大会 合同大会 2023)
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低分子量G蛋白質RAC3の病的バリアントによる発達障害の病態形成機構
(第65回日本小児神経学会学術集会 2023)
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PLEKHG2ミスセンス変異による神経発達障害の発症メカニズム
(第65回日本小児神経学会学術集会 2023)
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Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
(2023)
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Expression distribution of the Rac regulatory molecule Rich2 changes with neurodevelopment
(The 46th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2023) 2022)
more...
Education (3):
- 2016 - 2019 Gifu University
- 2014 - 2016 Nagoya University Graduare School of Pharmaceutical Sciences
- 2010 - 2014 Gifu University Faculty of Engineering
Professional career (1):
- Engineering (Gifu University)
Work history (3):
- 2022/06 - 現在 Nagoya University Division of Biological Sciences, Nagoya University Graduate School of Science, Nagoya Assistant professor
- 2020/04 - 2022/05 Institute for Developmental Research, Aichi Developmental Disability Center Department of Molecular Neurobiology Research resident
- 2018/04 - 2020/03 Japan Society for the Promotion of Science
Committee career (2):
- 2023/04 - 2026/03 日本臨床分子形態学会 評議員
- 2021/10 - 2021/10 日本臨床分子形態学会 第53回日本臨床分子形態学会総会・学術集会 実行委員
Awards (3):
- 2023 - The Japanese Society for Neurochemistry The Award for Young Investigator of Japanese Society for Neurochemistry Pathophysiological mechanisms underlying neurodevelopmental disorders caused by Rac GTPases dysregulation
- 2022/05 - 日本生化学会中部支部 奨励賞
- 2021/10 - The Japanese Society for Neurochemistry Best Presentation Award of The Japanese Society for Neurochemistry Pathophysiological significance of RAC3 variants in neurodevelopmental disorders
Association Membership(s) (4):
日本臨床分子形態学会
, 日本神経化学会
, 日本生化学会
, 日本分子生物学会
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