Rchr
J-GLOBAL ID：202001017615210907
Update date: Feb. 14, 2024
SHIRAKO SAKI
シラコ サキ | SHIRAKO SAKI
Affiliation and department：
Job title：
Assistant Professor
Research field (3)：
Environmental and pharmaceutical development resources
, Food sciences
, Analytical chemistry
Research keywords (6)：
Anti-inflammation
, Functional food
, Herbal medicine
, (Japanese) Kampo medicine
, Peptide
, Peptide、 (Japanese) Kampo medicine、 Herbal medicine、 Functional food、 Anti-inflammation
Research theme for competitive and other funds (4)：
- 2022 - 2025 Effect of decarboxylated amino acids found in Ziziphus jujuba for the improvement of frailty.
- 2022 - 回腸を標的とするピログルタミルペプチドによる腸内細菌叢改善作用メカニズムの解明
- 2021 - 2022 “新規ロイシン誘導体”が秘める生理機能の解明に向けた基礎研究
- 2020 - 2021 炎症性腸疾患の予防および治療を目指した生薬由来ペプチドの網羅的探索
Papers (8)：
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Ozaki H, Nishidono Y, Fujii A, Okuyama T, Nakamura K, Maesako T, Shirako S, Nakatake R, Tanaka K, Ikeya Y, et al. Identification of Anti-Inflammatory Compounds from Peucedanum praeruptorum Roots by Using Nitric Oxide-Producing Rat Hepatocytes Stimulated by Interleukin 1β. Molecules. 2023. 28. 13. 5076
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Tatsuki Sato, Saki Shirako, Tetsuya Okuyama, Yukinobu Ikeya, and Mikio Nishizawa. Anti-inflammatory effects of hydrophobic constituents in the extract of the root cortex of Paeonia suffruticosa. Bioactive Compounds in Health and Disease. 2022. 5. 8. 160-173
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Yuto Nishidono, Yuuna Iwama, Saki Shirako, Toshinari Ishii, Tetsuya Okuyama, Mikio Nishizawa & Ken Tanaka. Two new monoterpene esters from the pericarps of <I>Alpinia zerumbet</I>. Natural Product Research. 2022
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Siti Mariyah Ulfa, Saki Shirako, Mariko Sato, Dinia Rizqi Dwijayanti, Tetsuya Okuyama, Seiji Horie, Jun Watanabe, Yukinobu Ikeya, Mikio Nishizawa. Anti-inflammatory effects of anthraquinones of Polygonum multiflorum roots. Bioactive Compounds in Health and Disease. 2022. 5. 6. 136-148
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Saki Shirako, Kenji Sato, Saki Moriwaki, Yukinobu Ikeya, Mikio Nishizawa. Detection of Decarboxylated Amino Acids after in Vitro Protease Digestion of the Hydrophilic Fraction of Crude Drug Extracts. Biological and Pharmaceutical Bulletin. 2022. 45. 2. 169-177
ｍore...
MISC (2)：
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Yifeng ZHEN, Saki SHIRAKO, and Kenji SATO. Recent Advances on Biological Functions of Peptides and Amino Acid Derivatives in Fermented Products Using Aspergillus Starter. 2022. 117. 1. 6-17
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白子紗希, 佐藤健司. [最近の研究] ジ・トリペプチドによって活性化/阻害されるオリゴペプチド(4残基以上)トランスポーターの存在とその意義. 食品加工技術. 2019. 39. 2. 9-17
Books (1)：
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Pyroglutamyl peptides in Japanese fermented foods and protein hydrolysate enhance production of host-antimicrobial peptides and ameliorate microbial imbalance
Elsevier Science, Academic Press 2021 ISBN:9780128212325
Lectures and oral presentations (34)：
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初代培養肝細胞における一酸化窒素誘導抑制作用を持つゼンコの成分の探索
(第45回 日本分子生物学会年会(日本分子生物学会) 2022)
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ゴーヤー果実成分によるインスリン感受性改善効果および肝糖新生抑制効果
(第45回 日本分子生物学会年会(日本分子生物学会) 2022)
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Comprehensive analysis of Hydrophilic Fraction of Crude Drug Extracts based on digestion and absorption processes
(2022 General Assembly of the European Society of Medicine (ESMED General Assembly) 2022)
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Constituents that suppress nitric oxide production in green perilla and red perilla
(The 30th Annual Meeting of International Congress on Nutrition and Integrative Medicines 2022)
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LC-MS/MS analyses of i<I>n vitro</I> protease digests of ECLM, EAS, and OPLEF
(The 30th Annual Meeting of International Congress on Nutrition and Integrative Medicines 2022)
ｍore...
Education (3)：
- - 2020 Kyoto University Graduate School of Agriculture Division of Applied Biosciences
- - 2017 Kyoto University Graduate School of Agriculture Division of Applied Biosciences
- - 2015 Kyoto Prefectural University Faculty of Life and Environmental Sciences Department of Food Sciences and Nutritional Health
Professional career (1)：
- Ph.D. (Agriculture) (Kyoto University)
Work history (1)：
- 2020/04 - Ritsumeikan University College of Life Sciences Assistant Professor
Awards (5)：
- 2022/07 - International Congress on Nutrition and Integrative Medicine Young Investigator Award 2022
- 2019/12 - ICoFF2019 Young Investigator Award Pyroglutamyl peptides with anti-obesity, which are distributed in Japanese fermented foods, regulate ERK phosphorylation through GPR109A and GPR81
- 2018/11 - 2018 Global Food Science Student Competition (GFSSC) in Jiangnan University(中国) 口頭発表銅賞 Administration of pyroGlu-Leu, distributed in fermented foods, increases antimicrobial peptides, Rattusin, and improves high fat diet induced-dysbiosis in rats
- 2017/10 - ISNFF2017 Poster Award (First place) Oral administration of pyroGlu-Leu, widely distributed in protein hydrolysates and fermented foods, increases antimicrobial peptides in rat small intestine
- 2015/11 - ICoFF2015 Poster Award Identification of glutathione-binding protein in human plasma after supplementation of glutathione
Association Membership(s) (2)：
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