Rchr
J-GLOBAL ID：202001017724457840
Update date: Jun. 11, 2024
Kakiuchi Yuji
カキウチ ユウジ | Kakiuchi Yuji
Affiliation and department：
Job title：
医員
Research theme for competitive and other funds (3)：
- 2021 - 2024 mTOR阻害薬テムシロリムスによる椎間板変性に対する治療アプローチ
- 2020 - 2023 徐放化抗がん剤と非金属脊椎インプラントを併用した新しい脊椎転移治療に関する研究
- 2020 - 2023 アディポネクチンによる椎間板変性・炎症に対する治療法の開発
Papers (23)：
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Kunihiko Miyazaki, Shingo Miyazaki, Takashi Yurube, Yoshiki Takeoka, Yutaro Kanda, Zhongying Zhang, Yuji Kakiuchi, Ryu Tsujimoto, Hiroki Ohnishi, Tomoya Matsuo, et al. Protective Effects of Growth Differentiation Factor-6 on the Intervertebral Disc: An In Vitro and In Vivo Study. Cells. 2022. 11. 7
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Yutaro Kanda, Takashi Yurube, Yusuke Morita, Yoshiki Takeoka, Takuto Kurakawa, Ryu Tsujimoto, Kunihiko Miyazaki, Yuji Kakiuchi, Shingo Miyazaki, Zhongying Zhang, et al. Delayed notochordal cell disappearance through integrin α5β1 mechanotransduction during ex-vivo dynamic loading-induced intervertebral disc degeneration. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021. 39. 9. 1933-1944
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Takashi Yurube, Hiroaki Hirata, Masaaki Ito, Yoshiki Terashima, Yuji Kakiuchi, Ryosuke Kuroda, Kenichiro Kakutani. Involvement of Autophagy in Rat Tail Static Compression-Induced Intervertebral Disc Degeneration and Notochordal Cell Disappearance. International journal of molecular sciences. 2021. 22. 11
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Masaaki Ito, Takashi Yurube, Yutaro Kanda, Yuji Kakiuchi, Yoshiki Takeoka, Toru Takada, Ryosuke Kuroda, Kenichiro Kakutani. Inhibition of Autophagy at Different Stages by ATG5 Knockdown and Chloroquine Supplementation Enhances Consistent Human Disc Cellular Apoptosis and Senescence Induction rather than Extracellular Matrix Catabolism. International journal of molecular sciences. 2021. 22. 8
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Yoshiki Takeoka, Takashi Yurube, Koichiro Maeno, Yutaro Kanda, Ryu Tsujimoto, Kunihiko Miyazaki, Yuji Kakiuchi, Shingo Miyazaki, Zhongying Zhang, Toru Takada, et al. Improved bone bonding of hydroxyapatite spacers with a high porosity in a quantitative computed tomography-image pixel analysis: A prospective 1-year comparative study of the consecutive cohort undergoing double-door cervical laminoplasty. JOR spine. 2020. 3. 1. e1080
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MISC (7)：
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The therapeutic strategy for spinal cord compression. Bone joint nerve : BJN. 2020. 10. 3. 469-476
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The Effectiveness and Limitation of Spine Surgery for Spinal Metastasis. Journal of spine research : official journal of the Japanese Society for Spine Surgery and Related Research. 2019. 10. 5. 898-904
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角谷 賢一朗, 由留部 崇, 張 鐘穎, 宮崎 真吾, 高田 徹, 垣内 裕司, 武岡 由樹, 神田 祐太郎, 辻本 龍, 鈴木 哲平, et al. 筋ジストロフィーに伴う脊柱変形の手術経験. Journal of Spine Research. 2019. 10. 3. 318-318
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由留部 崇, 伊藤 雅明, 渡邉 信佳, 竹岡 亨, 角谷 賢一朗, 高田 徹, 垣内 裕司, 武岡 由樹, 神田 裕太郎, 黒田 良祐, et al. ロコモティブシンドロームに対するロコモ体操の脊椎・骨盤・下肢矢状断アライメント改善効果. 日本整形外科学会雑誌. 2018. 92. 3. S632-S632
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高田 徹, 角谷 賢一朗, 由留部 崇, 伊藤 雅明, 垣内 裕司, 武岡 由樹, 神田 裕太郎, 黒田 良祐, 西田 康太郎. 仙骨骨折を合併した骨盤輪骨折に対するSacral-Aal-Iliac Screwを用いた腰仙椎後側法固定術の有用性. Journal of Spine Research. 2018. 9. 3. 478-478
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Lectures and oral presentations (2)：
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Pharmacological inhibition of mTORC1 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction
(46th International Society for the Study of the Lumbar Spine Annual Meeting 2019)
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Temsirolimus Is a Candidate of the Optimal mTOR Inhibitor to Protect Human Disc Cells Depending on Akt and Autophagy Induction
(The 48th Annual Meeting of the Japanese Society for Spine Surgery and Related Research 2019)
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