Mori Kenji

モリケンジ | Mori Kenji

Affiliation and department：
Job title：室長

Research field (2)： Metabolism and endocrinology , Medical biochemistry

Research keywords (4)： GPCR , オーファン受容体 , 神経ペプチド , 生理活性ペプチド

Research theme for competitive and other funds (10)：

2021 - 2024 Studies on the regulatory mechanisms by novel bioactive peptide and receptor systems
2018 - 2021 Studies on the biological regulatory mechanisms by a novel bioactive peptide, neuromedin U precursor-related peptide (NURP)
2015 - 2019 Studies on molecular functions of mid-size peptides derived from living system and their basic research for practical drug discovery
2015 - 2018 Studies on the regulatory mechanisms of physiological processes by newly identified bioactive peptide
2013 - 2016 The search for the novel bioactive peptide that activates G protein-coupled receptor coupled to G12/13 proteins

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Papers (39)：

Yukie Tanaka, Shimon Taguchi, Keisuke Maruyama, Kenji Mori, Mikiya Miyazato, Kenji Kangawa, Noboru Murakami, Keiko Nakahara. Comparison of physiological functions between neuromedin U-related peptide and neuromedin S-related peptide in the rat central nervous system. Biochemical and biophysical research communications. 2021. 534. 653-658
Kentaro Takayama, Kenji Mori, Tomo Asari, Yuko Sohma, Erina Nomura, Yu Sasaki, Akihiro Taguchi, Atsuhiko Taniguchi, Mikiya Miyazato, Naoto Minamino, et al. Design and synthesis of peptidic partial agonists of human neuromedin U receptor 1 with enhanced serum stability. Bioorganic & medicinal chemistry letters. 2020. 30. 18. 127436-127436
Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata, et al. Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode. Nature communications. 2020. 11. 1. 4160-4160
Kentaro Takayama, Kenji Mori, Akiko Tanaka, Yu Sasaki, Yuko Sohma, Akihiro Taguchi, Atsuhiko Taniguchi, Toshiyasu Sakane, Akira Yamamoto, Mikiya Miyazato, et al. A chemically stable peptide agonist to neuromedin U receptor type 2. Bioorganic & medicinal chemistry. 2020. 28. 10. 115454-115454
Madoka Anan, Ryoko Higa, Kenshiro Shikano, Masahito Shide, Akinobu Soda, Magdeline E Carrasco Apolinario, Kenji Mori, Toshitaka Shin, Mikiya Miyazato, Hiromitsu Mimata, et al. Cocaine has some effect on neuromedin U expressing neurons related to the brain reward system. Heliyon. 2020. 6. 5. e03947

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MISC (17)：

延生卓也, 日野純, 白井学, 細田洋司, 森健二, 南野直人, 宮里幹也, 寒川賢治. 血管内皮細胞由来C型ナトリウム利尿ペプチド(CNP)は腎臓疾患による腎線維化を抑制する. 日本内分泌学会雑誌. 2020. 96. 1
森健二. プロラクチン分泌促進活性を持つ新たな生理活性ペプチドの発見. 生化学. 2019. 91. 5. 697-700
児島将康, 森健二. 【拡がりゆく神経内分泌学の現状と展望】ニューロメジンの種類とその生理作用. 内分泌・糖尿病・代謝内科. 2014. 39. 1. 26-32
寺西仁志, Stanojevic Boban, 天野雄一郎, 兎澤隆一, 森健二, 日野純, 宮澤崇, 宮里幹也, 花田礼子, 寒川賢治, et al. 末梢におけるニューロメジンUシステムのNAFLD/NASHへの関与. 肥満研究. 2013. 19. Suppl. 179-179
森健二, 宮里幹也, 寒川賢治, 児島将康. 【内分泌ホルモンのすべて】(第3章)中枢神経ホルモン視床下部ホルモンニューロメジン. 内分泌・糖尿病・代謝内科. 2013. 36. Suppl.4. 127-133

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Education (3)：

- 1999 The University of Tokushima Graduate School of Engineering
- 1996 The University of Tokushima Graduate School of Engineering
- 1994 The University of Tokushima Faculty of Engineering Department of Biological Science and Technology

Professional career (1)：

博士(工学) (徳島大学)

Work history (4)：

2007/04 - 現在国立循環器病研究センター研究所生化学部室長
2005/03 - 2007/03 国立循環器病研究センター研究所生化学部室員
2001/04 - 2005/02 国立循環器病研究センター研究所生化学部派遣研究員
1999/04 - 2001/03 国立循環器病研究センター研究所生化学部流動研究員

Awards (3)：

2011 - 国立循環器病研究センター若手研究奨励賞
2006 - メタボリックシンドロームカンファレンス若手研究奨励賞
2005/07 - 日本内分泌学会若手研究奨励賞

Association Membership(s) (4)：

日本分子生物学会 , 日本生化学会 , 日本神経内分泌学会 , 日本内分泌学会

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