Kobayashi-Ujiie Yuka

ウジイエユカ | Kobayashi-Ujiie Yuka

Affiliation and department：
Job title：外来研究員
Research theme for competitive and other funds (9)：

2023 - 2026 髄鞘形成グリアの新規転写因子解析から紐解く末梢神経障害の病態解明
2019 - 2023 末梢神経髄鞘化における新規シュワン細胞分化制御因子の探索
2016 - 2019 Hypoxia induced factor 1 alpha participates in Schwann cells differentiation in peripheral nerves.
2013 - 2016 Matrix metalloprotease 12 is a novel prospective molecule regulating neuropathic pain
2012 - 2015 Identification of crosstalk between pathological angiogenesis and neurons in regulating chronic pain

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Papers (32)：

Yurika Numata-Uematasu, Shuji Wakatsuki, Yuka Kobayashi-Ujiie, Kazuhisa Sakai, Noritaka Ichinohe, Toshiyuki Araki. In vitro myelination using explant culture of dorsal root ganglia: An efficient tool for analyzing peripheral nerve differentiation and disease modeling. PLOS ONE. 2023. 18. 5. e0285897-e0285897
Maho Tsubota, Ryotaro Fukuda, Yusuke Hayashi, Takaya Miyazaki, Shin Ueda, Rika Yamashita, Nene Koike, Fumiko Sekiguchi, Hidenori Wake, Shuji Wakatsuki, et al. Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants. Journal of neuroinflammation. 2019. 16. 1. 199-199
Norikazu Kiguchi, Fumihiro Saika, Yuka Kobayashi, Mei-Chuan Ko, Shiroh Kishioka. TC-2559, an α4β2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1β through STAT3 inhibition in cultured murine macrophages. Journal of pharmacological sciences. 2015. 128. 2. 83-6
Yuka Kobayashi, Norikazu Kiguchi, Yohji Fukazawa, Fumihiro Saika, Takehiko Maeda, Shiroh Kishioka. Macrophage-T cell interactions mediate neuropathic pain through the glucocorticoid-induced tumor necrosis factor ligand system. The Journal of biological chemistry. 2015. 290. 20. 12603-13
Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Haruka Sakaguchi, Takehiko Maeda, Shiroh Kishioka. Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain. Pain. 2015. 156. 4. 684-693

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MISC (19)：

Ujiie-Kobayashi Yuka, Wakatsuki Shuji, Araki Toshiyuki. HIF1α as a potential regulator of Schwann cell differentiation in peripheral nerve. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-P-017
氏家悠佳, 若月修二, 荒木敏之. 低酸素応答による末梢神経の髄鞘形成制御. 日本応用酵素協会誌. 2019. 53. 27-32
Yuka Kobayashi, Norikazu Kiguchi, Fumihiro Saika, Shiroh Kishioka. Exploration of novel therapeutic targets for neuropathic pain based on the regulation of immune cells. JAPANESE JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2015. 35. 3. 65-72
小林悠佳, 木口倫一, 雑賀史浩, 岸岡史郎. 免疫細胞制御に基づく神経障害性疼痛治療標的の探索. 日本神経精神薬理学雑誌. 2015. 35. 3. 65-72
小林悠佳, 岸岡史郎. 新規疼痛制御分子としてのマクロファージ由来マトリックスメタロプロテアーゼ12の可能性. PAIN RESEARCH. 2015. 30. 1. 37-45

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Lectures and oral presentations (3)：

低酸素応答によるミエリン形成制御
(第五回日本ミエリン研究会大会)
Hypoxia induced factor 1α regulates Schwann cell differentiation in peripheral nerves.
(第24回グリア研究会)
Hypoxia-inducible factor 1 alpha promotes peripheral nerve myelination
(XIV European Meeting on Glial Cells in Health and Disease)

Awards (2)：

2021/03 - The 42th Annual Scientific Meeting National Institute of Neuroscience National Center of Neurology and Psychiatry. 優秀ポスター賞
2014/06 - 第36回日本疼痛学会優秀論文賞

Association Membership(s) (3)：

日本疼痛学会 , 日本神経科学会 , 日本薬理学会

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