Morishima Nobuhiro

モリシマノブヒロ | Morishima Nobuhiro

Affiliation and department：

Research field (4)： Cell biology , Molecular biology , Medical biochemistry , Environmental effects of radiation

Research keywords (6)：細胞ストレス , アポトーシス , 小胞体 , 細胞分化 , 骨格筋 , プロテインアレイ

Research theme for competitive and other funds (9)：

2022 - 2025 細胞の慢性的ストレス応答を指標とした低線量率放射線生物影響の精密定量解析
2017 - 2023 筋分化過程に必須な小胞体カルシウム枯渇の分子基盤と細胞内情報伝達における役割
2015 - 2018 Signaling induced by calcium depletion from the endoplasmic reticulum: regulation mechanisms and its roles in myoblast differentiation
2013 - 2017 Regulation of myoblast differentiation through the endoplasmic reticulum (ER) membrane dynamics caused by ER stress
2012 - 2016 Identification of the ER signaling system that regulates cell fate decision

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Papers (9)：

Nobuhiro Morishima, Keiko Nakanishi. Proplatelet formation in megakaryocytes is associated with endoplasmic reticulum stress. Genes to cells : devoted to molecular & cellular mechanisms. 2016. 21. 7. 798-806
Keiko Nakanishi, Kisa Kakiguchi, Shigenobu Yonemura, Akihiko Nakano, Nobuhiro Morishima. Transient Ca2+ depletion from the endoplasmic reticulum is critical for skeletal myoblast differentiation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015. 29. 5. 2137-49
Nobuhiro Morishima, Keiko Nakanishi. Significance of ER Ca(2+) outflow during myogenesis. Channels (Austin, Tex.). 2015. 9. 4. 173-4
Nobuhiro Morishima, Keiko Nakanishi, Akihiko Nakano. Activating transcription factor-6 (ATF6) mediates apoptosis with reduction of myeloid cell leukemia sequence 1 (Mcl-1) protein via induction of WW domain binding protein 1. The Journal of biological chemistry. 2011. 286. 40. 35227-35
Keiko Nakanishi, Naoshi Dohmae, Nobuhiro Morishima. Endoplasmic reticulum stress increases myofiber formation in vitro. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2007. 21. 11. 2994-3003

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MISC (6)：

森島信裕. 【筋骨格系と小胞体ストレス】筋と小胞体ストレス筋肉細胞の分化と小胞体ストレス. THE BONE. 2018. 32. 2. 197-201
森島信裕, 馬替純二, 伊藤嘉浩, 緒方裕光. 小グループの選抜タンパク質を精密定量し、微弱で慢性的な細胞ストレスが細胞生理に与える影響を定量評価する. 生命科学系学会合同年次大会. 2017. 2017年度. [4LT27-1330)]
森島信裕. 巨核球内へのストレス負荷を利用した血小板形成法の開発. 血液医学研究年報. 2014. 6. 48-49
森島信裕. 【細胞とヒトの多様なストレス応答】細胞のストレス応答細胞ストレスによる分化誘導. Surgery Frontier. 2013. 20. 4. 383-388
森島信裕. 【細胞死研究総集編】細胞死の関わる生命現象発生における細胞死筋分化過程での細胞運命決定にかかわる小胞体ストレスシグナル. 実験医学. 2010. 28. 7. 1085-1091

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Education (2)：

Professional career (1)：

Association Membership(s) (3)：

アメリカ生化学・分子生物学会 , 日本生化学会 , 日本分子生物学会

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