Rchr
J-GLOBAL ID：202001018790899213
Update date: May. 28, 2024
Okabe Atsushi
オカベ アツシ | Okabe Atsushi
Affiliation and department：
Job title：
Associate Professor
Other affiliations (1)：
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Chiba University
Department of Molecular Oncology, Graduate School of Medicine
Associate Professor
Research field (1)：
Genomics
Research theme for competitive and other funds (7)：
- 2022 - 2025 癌ウイルスによるクロマチン構造破綻が誘導する新規発癌機構の解明
- 2020 - 2023 和漢薬からのエピゲノムを標的とする新規抗癌薬の探索及び作用機序の解明
- 2019 - 2021 Analysis of epigenetic aberrations induced by oncovirus infection
- 2017 - 2019 Roles of TET family in dynamic epigenomic alteration induced by EB virus infection
- 2017 - 2019 Analysis of Ras/Raf-induced senescence by activated JAG1-Notch signaling
- 2019 - 2019 胃癌におけるクロマチン構造異常による癌化機構の解明
- 2014 - 2016 Analysis on alterated chromatin status of viral genome in the host cells.
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Papers (63)：
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Tianhui Zhu, Atsushi Okabe, Genki Usui, Ryoji Fujiki, Daichi Komiyama, Kie Kyon Huang, Motoaki Seki, Masaki Fukuyo, Hiroyuki Abe, Meng Ning, et al. Integrated enhancer regulatory network by enhancer-promoter looping in gastric cancer. NAR cancer. 2024. 6. 2. zcae020
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Sanji Kanaoka, Atsushi Okabe, Manato Kanesaka, Bahityar Rahmutulla, Masaki Fukuyo, Motoaki Seki, Takayuki Hoshii, Hiroaki Sato, Yusuke Imamura, Shinichi Sakamoto, et al. Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer. Cancer Letters. 2024. 588. 216815-216815
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Harue Mizokami, Atsushi Okabe, Ruchi Choudhary, Masato Mima, Kenta Saeda, Masaki Fukuyo, Bahityar Rahmutulla, Motoaki Seki, Boon-Cher Goh, Satoru Kondo, et al. Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma. eBioMedicine. 2024. 102. 105057-105057
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Kazuto Suda, Atsushi Okabe, Junichi Matsuo, Linda Shyue Huey Chuang, Ying Li, Nawaphat Jangphattananont, Naing Naing Mon, Khine Nyein Myint, Akihiro Yamamura, Jimmy Bok-Yan So, et al. Aberrant upregulation of RUNX3 activates developmental genes to drive metastasis in gastric cancer. Cancer research communications. 2024
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Kouichi Kitamura, Tyuji Hoshino, Atsushi Okabe, Masaki Fukuyo, Bahityar Rahmutulla, Nobuko Tanaka, Sohei Kobayashi, Tomoaki Tanaka, Takashi Shida, Mashiro Ueda, et al. The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer. International journal of molecular sciences. 2023. 24. 24
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MISC (26)：
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美馬 勝人, 岡部 篤史, 中川 拓也, 黒川 友哉, 近藤 悟, 溝上 晴恵, 福世 真樹, 繩井 バハテヤリラヒムトラ, 星居 孝之, 三澤 清, et al. HPV挿入部位周辺のエピジェネティックな活性化による頭頸部扁平上皮癌発癌機構(Epigenetic activation of regions surrounding HPV integrated sites contributes to tumorigenesis of HNSCC). 日本癌学会総会記事. 2022. 81回. P-1293
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美馬 勝人, 岡部 篤史, 中川 拓也, 黒川 友哉, 近藤 悟, 溝上 晴恵, 福世 真樹, 縄井 バハテヤリ・ラヒムトラ, 星居 孝之, 三澤 清, et al. 頭頸部扁平上皮癌においてHPV挿入が引き起こす発癌分子機構の解析. 日本癌学会総会記事. 2021. 80回. [P14-4]
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眞野恭伸, 眞野恭伸, 福世真樹, 岡部篤史, 松坂恵介, 山中遼太, 油谷浩幸, 金田篤志, 金田篤志. KRAS(+)膵臓癌細胞株がJAG1-Notchシグナル活性化を介して正常細胞に及ぼす役割. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
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美馬勝人, 岡部篤史, 星居孝之, 中川拓也, 黒川友哉, 近藤悟, 福世真樹, RAHMUTULLA Bahityar, 藤木亮次, 三澤清, et al. Features of 3-D chromatin structure in HPV-associated head and neck squamous cell carcinoma. 日本消化器癌発生学会総会プログラム・抄録集. 2020. 31st
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OKABE Atsushi, HUANG Kie Kyon, MATSUSAKA Keisuke, FUKUYO Masaki, RAHMUTULLA Bahityar, HOSHII Takayuki, TAN Patrick, KANEDA Atsushi. Heterochromatin reprogramming and chromatin structural rewiring induced by oncovirus infection in gastric adenocarcinoma. 日本消化器癌発生学会総会プログラム・抄録集. 2020. 31st
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Education (3)：
- 2008 - 2012 The University of Tokyo The Graduate School of Engineering Department of Advanced Interdisciplinary Studies
- 2004 - 2006 International Christian University
- 2000 - 2004 International Christian University
Work history (4)：
- 2023/10 - 現在 Chiba University Health and Disease Omics Center Associate Professor
- 2018/04 - 2023/09 Chiba University
- 2015/11 - 2018/03 Chiba University
- 2012/04 - 2015/10 The University of Tokyo
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