Rchr
J-GLOBAL ID：202001018975406396
Update date: Jan. 31, 2024
Balan Shabeesh
Balan Shabeesh | Balan Shabeesh
Affiliation and department：
Job title：
Research Scientist
Research theme for competitive and other funds (3)：
- 2019 - 2021 Autism Spectrum Disorders (ASD) associated rare loss of function genetic variant in SUV39H2; a putative role of H3K9 methylation dynamics in ASD pathogenesis
- 2014 - 2017 Quantitative trait loci analysis of prepulse inhibition using exome data from inbred mouse strains and its application to the identification of schizophrenia susceptibility genes
- 2014 - 2016 Additional genetic defects outside commonly deleted region in 22q11.2 deletion with psychosis; a prospect for identifying novel schizophrenia candidate genes
Papers (41)：
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Shabeesh Balan, Yoshimi Iwayama, Tetsuo Ohnishi, Mikiko Fukuda, Atsuko Shirai, Ayumi Yamada, Sara Weirich, Maren Kirstin Schuhmacher, Kalarickal Vijayan Dileep, Toshihiro Endo, et al. A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin β-cluster genes in the developing brain. Molecular psychiatry. 2021. 26. 12. 7550-7559
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Tomonori Hara, Manabu Toyoshima, Yasuko Hisano, Shabeesh Balan, Yoshimi Iwayama, Harumi Aono, Yushi Futamura, Hiroyuki Osada, Yuji Owada, Takeo Yoshikawa. Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons. Translational Psychiatry. 2021. 11. 1. 275-275
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Ohnishi T, Kiyama Y, Arima-Yoshida F, Kadota M, Ichikawa T, Yamada K, Watanabe A, Ohba H, Tanaka K, Nakaya A, et al. Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia. EMBO molecular medicine. 2021. 13. 4. e12574
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Shabeesh Balan, Tetsuo Ohnishi, Akiko Watanabe, Hisako Ohba, Yoshimi Iwayama, Manabu Toyoshima, Tomonori Hara, Yasuko Hisano, Yuki Miyasaka, Tomoko Toyota, et al. Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition, and Implication of CDH23 in Schizophrenia. Schizophrenia Bulletin. 2021. 47. 4. 1190-1200
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Ogata, Shigehiro, Hashizume, Koichi, Hayase, Yoneko, Kanno, Yukie, Hori, Kei, Balan, Shabeesh, Yoshikawa, Takeo, Takahashi, Hidehiko, Taya, Shinichiro, Hoshino, Mikio. Potential involvement of DSCAML1 mutations in neurodevelopmental disorders. Genes to Cells. 2021. n/a. n/a. 136-151
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MISC (6)：
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Shabeesh Balan, Tetsuo Ohnishi, Akiko Watanabe, Hisako Ohba, Yoshimi Iwayama, Yasuko Hisano, Tomoko Toyota, Manabu Toyoshima, Tomomi Shimogori, Takeshi Hayashi, et al. Genetic Deciphering of Prepulse Inhibition Reveals the Putative Role of an Atypical Cadherin in Schizophrenia Pathogenesis. BIOLOGICAL PSYCHIATRY. 2020. 87. 9. S398-S398
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豊島学, 蒋緒光, 小川覚之, 大西哲生, 吉原壯悟, SHABEESH Balan, 廣川信隆, 吉川武男. カルボニルストレス性統合失調症の発症脆弱性に関わるCRMP2の機能異常. 統合失調症研究. 2020. 10. 1
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豊島学, JIANG Xuguang, 小川覚之, 大西哲生, 吉原壯悟, BALAN Shabeesh, 吉川武男, 廣川信隆. カルボニルストレス性統合失調症におけるタンパク質分子病態解析. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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大西哲生, 城山優治, 有馬(吉田)史子, 門田満隆, 田中かおり, 山田一之, 山田一之, 市川智恵, 新井誠, 中谷明弘, et al. 脳における新たな遺伝子発現制御システム「LDB2-EGR軸」と精神疾患の病態生理における役割. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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Shabeesh Balan, Yoshimi Iwayama, Mikiko Fukuda, Atsuko Shirai, Kaoru Kotoshiba, Motoko Maekawa, Tomoko Toyota, Tetsuo Ohnishi, Manabu Toyoshima, Yoichi Shinkai, et al. Targeted re-sequencing of genes involved in H3K9 methylation machinery in autism spectrum disorders reveal a loss of function variant in SUV39H2. HUMAN GENOMICS. 2018. 12
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