Rchr
J-GLOBAL ID：202001019074758478
Update date: Jun. 06, 2024
KAWAGOE FUMIHIRO
カワゴエ フミヒロ | KAWAGOE FUMIHIRO
Affiliation and department：
Job title：
助教
Research theme for competitive and other funds (1)：
- 2022 - 2024 fluorovitamin D3
Papers (24)：
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Fumihiro Kawagoe, Sayuri Mototani, Yasushi Takemoto, Motonari Uesugi, Atsushi Kittaka. Improved and scalable synthesis of potent SREBP inhibitor KK-052 via [3+2] cycloaddition. Synthesis. 2024. 56. 9. 1460
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Fumihiro Kawagoe, Sayuri Mototani, Atsushi Kittaka. Efficient Stereo-Selective Fluorination on Vitamin D3 Side-Chain Using Electrophilic Fluorination. Biomolecules. 2024. 14. 1. 37-37
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Fumihiro Kawagoe, Sayuri Mototani, Kaori Yasuda, Akiko Takeuchi, Hiroki Mano, Shinji Kakuda, Hiroshi Saitoh, Toshiyuki Sakaki, Atsushi Kittaka. Synthesis of (22R)-, (22S)-22-Fluoro-, and 22,22-Difluoro-25-hydroxyvitamin D3 and Effects of Side-Chain Fluorination on Biological Activity and CYP24A1-Dependent Metabolism. The Journal of Organic Chemistry. 2023. 88. 17. 12394-12408
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Fumihiro Kawagoe, Sayuri Mototani, Aileen Mendoza, Yasushi Takemoto, Motonari Uesugi, Atsushi Kittaka. Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052. RSC Medicinal Chemistry. 2023. 14. 2030-2034
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Fumihiro Kawagoe, Sayuri Mototani, Kaori Yasuda, Hiroki Mano, Akiko Takeuchi, Hiroshi Saitoh, Toshiyuki Sakaki, Atsushi Kittaka. 【Featured Article】Synthesis of new 26,27-difluoro- and 26,26,27,27-tetrafluoro-25-hydroxyvitamin D3 : Effects of terminal fluorine atoms on biological activity and half-life. Chemical and Pharmaceutical Bulletin. 2023. 71. 717-723
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MISC (17)：
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Farumashia. Farumashia. 2023. 59. 12. 1121
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fumihiro kawagoe, kittaka Atsushi. Chemistry of fluorinated vitamin D derivatives. VITAMINS. 2022. 96. 7. 296-304
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Fumihiro Kawagoe, Sayuri Mototani, Kittaka Atsushi. Efficient fluorination of vitamin D3 side chains. The allergy in practice. 2022. 42. 5. 58-63
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高田一成, 萩原雪乃, 冨樫萌香, 橘高敦史, 川越文裕, 上杉志成, 上杉志成, 楠瀬翔一, 東達也. Major Vitamin D3 Metabolites Liberated in Human Urine after GUS Treatment. JSBMS Letters. 2022. 47. Supplement
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岩井悠一郎, 大下遥己, 真野寛生, 川越文裕, 高野真史, 橘高敦史, 榊利之, 安田佳織. 側鎖にフッ素を有するビタミンD誘導体の代謝およびヒト乳がん細胞株に対する増殖抑制効果. ビタミン. 2022. 96. 4
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Patents (9)：
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CD環側鎖置換ビタミンD誘導体含有IL-19分泌抑制剤
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脂質生合成を選択的に阻害するビタミンD誘導体
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VDR-SILENT VITAMIN D DERIVATIVE AS INHIBITORS OF SREBP AND PHARMACEUTICAL USE THEREOF
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CD環側鎖置換ビタミンD誘導体
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ビタミンDラクトンによる脂質蓄積
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Education (3)：
- 2020 - Teikyo University Faculty of Pharma-Science
- 2006 - 2008 Chiba University Graduate School of Science
- 2002 - 2006 Chiba University Faculty of Science Department of Chemistry
Work history (4)：
- 2024/04 - 現在 Tokyo University of Science Faculty of Science, Division 2 Chemistry Assistant Professor
- 2020/12 - 2024/03 帝京大学薬学部 薬化学研究室 助教
- 2014/11 - 2020/03 帝京大学薬学部 薬化学研究室 AMED-CREST研究員
- 2008/04 - 2011/03 セントラル硝子株式会社
Awards (1)：
- 2023/11 - 有機合成化学協会 帝人ファーマ 研究企画賞
Association Membership(s) (4)：
日本薬学会医薬化学部会
, 有機合成化学協会
, 日本ビタミン学会
, 日本薬学会
