Murakami Masahiro

ムラカミマサヒロ | Murakami Masahiro

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (8)： oligolactate , drug delivery system , absorption imprivement , enteral delivery , lymphatic delivery , nucleic acid medicine , peptide delivery , antithrombosis

Research theme for competitive and other funds (6)：

2022 - 2025 多孔性ヤヌス微粒子による経口核酸デリバリーの最適化と吸収過程の局所モデル化の試み
2018 - 2021 Development of an oral nucleic acid delivery system accelerating the paradigm shift to nucleic acid pharmaceutical products
2012 - 2018 画期的な新規核酸医薬の分子技術の創出
2011 - 2013 肝臓に対する新規DDSを活用した経口遺伝子治療法の開発
2008 - 2012 新規siRNAテクノロジーを用いたC型肝炎の画期的治療法の開発

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Papers (52)：

Yi Cheng, Chie Watanabe, Yusuke Ando, Satoshi Kitaoka, Yuya Egawa, Tomoya Takashima, Akihiro Matsumoto, Masahiro Murakami. Caco-2 Cell Sheet Partially Laminated with HT29-MTX Cells as a Novel In Vitro Model of Gut Epithelium Drug Permeability. Pharmaceutics. 2023. 15. 9
Akihiro Matsumoto, Masahiro Murakami. Harmless and ecologically acceptable fabrication of long-acting injectable microspheres. Drug discoveries & therapeutics. 2023. 17. 3. 170-176
Junichiro Yamamoto, Wataru Shioyama, Hideo Ikarugi, Yoshinobu Ijiri, Muneshige Shimizu, Tomoya Takashima, Hiroyuki Kikukawa, Masahiro Murakami, Kazunori Otsui, Jaap Jan Zwaginga, et al. Investigations into the Pathomechanism of thrombotic Disorders with an Ex Vivo Global Test Performed from Non-Anticoagulated Blood: From Animal Experiments to Bedside Application. Acta Scientifci Nutritional Health. 2023. 7. 7. 119-127
Akihiro Matsumoto, Takeo Kitazawa, Yuta Hatori, Hiroshi Nakanishi, Chie Watanabe, Tomoya Takashima, Masahiro Murakami. Targeting cellular gaps using Janus nanoparticles containing cationic polymers and surfactant lipids. Drug discoveries & therapeutics. 2023. 17. 2. 104-113
Masahiro Murakami, Kazunori Otsui, Yoshinobu Ijiri, Muneshige Shimizu, Hideo Ikarugi, Wataru Shioyama, Junichiro Yamamoto, Kjell S Sakariassen. Global thrombosis test for assessing thrombotic status and efficacy of antithrombotic diet and other conditions. Future Science OA. 2022. 8. 3

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MISC (245)：

中森愛, 阪田凌央, 松本昭博, 北澤健生, 羽鳥勇太, 高島智也, 村上正裕. 細胞間隙指向性ヤヌスナノ粒子の調製. 日本DDS学会学術集会プログラム予稿集. 2023. 39th
北澤健生, 松本昭博, 羽鳥勇太, 高野幹久, 渡辺知恵, 高島智也, 村上正裕. Targeting cellular gaps using asymmetrical (Janus) nanoparticles in Caco-2 cells. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
津久井優希, 橋本拓馬, 安藤祐介, 北岡諭, 江川裕哉, CHENG Yi, 高島智之, 松本昭博, 渡辺知恵, 渡辺知恵, et al. Improvement of Caco-2 monolayer by partial lamination of HT29-MTX cells for evaluating intestinal epithelial drug permeability in vitro. 日本薬学会年会要旨集(Web). 2023. 143rd
高島智也, 松本昭博, 村上正裕. Inhibition of the human lactate dehydrogenase-A in vitro by oligo (lactic acid). 日本薬学会年会要旨集(Web). 2023. 143rd
村上正裕, 松本昭博, 渡辺知恵. Technical strategies for developing oral delivery systems for nucleic acid drugs. 月刊Precision Medicine. 2022. 5. 14. 1302-1305

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Books (1)：

オリゴ乳酸物語 : その発見から未来へ
東海大学出版会 2013 ISBN:9784486019886

Professional career (1)：

博士(薬学) (京都薬科大学)

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