Hemmi Hiroaki

ヘンミヒロアキ | Hemmi Hiroaki

Affiliation and department：

Research field (1)： Immunology

Research keywords (5)： Innate Immunity , Inflammation , Autoinflammatory diseases , Dendritic cells , Gentically modified mice

Research theme for competitive and other funds (10)：

2021 - 2024 免疫細胞分化・造血環境における免疫プロテアソーム機能的意義の解明
2019 - 2023 新規遺伝性インターフェロン制御異常症の同定と解析
2018 - 2021 Analysis of the immunoproteasome function in innate immunity
2016 - 2019 Elucidation of the pathological significance of a novel PSMB9 mutation in a sporadic case with Nakajo-Nishimura syndrome-like symptoms
2015 - 2018 Analysis of dendritic cell functions in peripheral tissues

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Papers (84)：

Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, Hiroaki Hemmi, et al. A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages. Cell Reports. 2024. 43. 4. 113981-113981
Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Takashi Orimo, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, et al. A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages. 2023
改正恒康, 金澤伸雄, 邊見弘明, 佐々木泉, 加藤喬, 山本明日美. 和歌山からの研究発信自己炎症性疾患. 和歌山医学. 2022. 73. 4. 135-135
Izumi Sasaki, Takashi Kato, Hiroaki Hemmi, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Asumi Yamamoto, Tsuneyasu Kaisho. Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis. Frontiers in immunology. 2022. 13. 857954-857954
Nobuo Kanazawa, Hiroaki Hemmi, Noriko Kinjo, Hidenori Ohnishi, Jun Hamazaki, Hiroyuki Mishima, Akira Kinoshita, Tsunehiro Mizushima, Satoru Hamada, Kazuya Hamada, et al. Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency. Nature communications. 2021. 12. 1. 6819-6819

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MISC (14)：

田村志宣, 山下友佑, 折茂貴是, 岩淵禎弘, 中嶋一貴, 佐々木泉, 邊見弘明, 橋本真一, 大島孝一, 改正恒康, et al. 原発性免疫不全症を基盤とするTh1型腸炎の病態解明. 日本血液学会学術集会抄録(Web). 2020. 82nd
田村志宣, 山下友佑, 福田有里, 小笹俊哉, 金澤伸雄, 安岡弘直, 邊見弘明, 大島孝一, 改正恒康, 園木孝志. 複合免疫不全症を来す新規LIG4症候群モデルマウスは炎症性腸疾患を自然発症する. 日本リンパ網内系学会会誌. 2019. 59
橋本大輝, Colet Jose Gabriel, 村嶋亜紀, 鈴木堅太郎, 山田源, 高浜洋介, 邊見弘明, 改正恒康, 高橋智. X線誘導性及び加齢性胸腺退縮におけるMaf遺伝子の機能解析. 和歌山医学. 2018. 69. 4. 197-198
邊見弘明, 山崎千尋, 星野克明, 改正恒康. 【樹状細胞と免疫制御-新たな展開】CD8陽性樹状細胞サブセットの動的制御機構の解析. Cytometry Research. 2012. 22. 1. 31-35
邊見弘明, 山崎千尋, 星野克明, 改正恒康. 樹状細胞と免疫制御免疫疾患の解明に向けた新たな展開 CD8陽性樹状細胞の動的制御機構の解析. Cytometry Research. 2011. 21. Suppl. 47-47

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