Rchr
J-GLOBAL ID:202001020246859911   Update date: May. 23, 2024

Ito Takeshi

イトウ タケシ | Ito Takeshi
Affiliation and department:
Job title: Assistant Professor
Research field  (2): Functional biochemistry ,  Bioorganic chemistry
Research keywords  (8): Protein-Ligand Interactions ,  Bioorganic Chemistry ,  Bacteroides ,  Gastrointestinal microbiome ,  Mitochondria ,  Bioactive compounds ,  Respiratory chain ,  Energy metabolism
Research theme for competitive and other funds  (1):
  • 2022 - 2025 Expression of malaria parasite mitochondrial protein in yeast and design of novel antimalarial compounds
Papers (15):
  • Takeshi Ito, Yuma Tojo, Minori Fujii, Kohei Nishino, Hidetaka Kosako, Yasuo Shinohara. Insights into the Mechanism of Catalytic Activity of Plasmodium Parasite Malate-Quinone Oxidoreductase. ACS Omega. 2024
  • Kiri Akieda, Kazuto Takegawa, Takeshi Ito, Gaku Nagayama, Naoshi Yamazaki, Yuka Nagasaki, Kohei Nishino, Hidetaka Kosako, Yasuo Shinohara. Unique Behavior of Bacterially Expressed Rat Carnitine Palmitoyltransferase 2 and Its Catalytic Activity. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 23-27
  • Takeshi Ito, Sayaka Kajita, Minori Fujii, Yasuo Shinohara. Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase. Microbiology Spectrum. 2023
  • Nicole L. Butler, Takeshi Ito, Sara Foreman, Joel E. Morgan, Dmitry Zagorevsky, Michael H. Malamy, Laurie E. Comstock, Blanca Barquera. Bacteroides fragilis Maintains Concurrent Capability for Anaerobic and Nanaerobic Respiration. Journal of Bacteriology. 2023. 205. 1
  • Kazuto Takegawa, Takeshi Ito, Atsushi Yamamoto, Naoshi Yamazaki, Mitsuru Shindo, Yasuo Shinohara. KH-17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane. Chemical Biology & Drug Design. 2023. 101. 4. 865-872
more...
Lectures and oral presentations  (23):
  • 完全長のパルミトイルカルニチントランスフェラーゼ2は大腸菌に発現させると不溶性画分に選択的に濃縮されるが触媒活性を保持している
    (第96回日本生化学会大会 2023)
  • 褐色脂肪組織を特徴づけるタンパク質の発現レベルの定量的評価に向けて
    (第96回日本生化学会大会 2023)
  • ボンクレキン酸がミトコンドリアのADP/ATP輸送体を阻害する際に重要となる部分構造
    (第96回日本生化学会大会 2023)
  • FoF1-ATP合成酵素のサブユニットcを標的として細胞内エネルギー代謝をコントロールする可能性
    (第1回生体機能解析産業研究会 2023)
  • Heterologous expression and function of Plasmodium parasite malate-quinone oxidoreductase in yeast mitochondria
    (The 2023 Annual Conference of the Japan Society for Bioscience, Biotechnology and Agrochemistry 2023)
more...
Education (3):
  • 2015 - 2018 Kyoto University Graduate School of Agriculture Division of Applied Life Sciences
  • 2013 - 2015 Kyoto University Graduate School of Agriculture Division of Applied Life Sciences
  • 2009 - 2013 Kochi University Faculty of Agriculture Department of Agriculture
Professional career (1):
  • Ph. D in Agriculture (Kyoto University)
Work history (5):
  • 2023/07 - 現在 Ehime University Graduate School of Agriculture Department of Bioscience Assistant Professor
  • 2020/11 - 2023/06 The University of Tokushima Faculty of Pharmaceutical Sciences Assistant Professor (Concurrent)
  • 2020/10 - 2023/06 The University of Tokushima Institute of Advanced Medical Sciences Assistant Professor
  • 2018/04 - 2020/09 Rensselaer Polytechnic Institute Center for Biotechnology and Interdisciplinary Sciences Postdoctoral Research Associate
  • 2016/04 - 2018/03 JSPS Research Fellowship for Young Scientists (DC2)
Association Membership(s) (5):
American Chemical Society ,  American Society for Microbiology ,  The Pharmaceutical Society of Japan ,  Pesticide Science Society of Japan ,  The Japan Society for Bioscience, Biotechnology, and Agrochemistry
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