Rchr
J-GLOBAL ID：202001021067840740
Update date: Feb. 01, 2024
Takikawa Kenji
タキカワ ケンジ | Takikawa Kenji
Affiliation and department：
Job title：
主任研究員
Homepage URL (1)：
https://www.tmghig.jp/research/team/roukanou-shinkeikagaku/roukashinkei/
Research field (2)：
Neuroscience - general
, Chemical biology
Research keywords (5)：
バイオイメージング
, 蛍光プローブ
, シナプス
, 開口放出
, ケミカルバイオロジー
Research theme for competitive and other funds (4)：
- 2021 - 2024 Optical analysis of synaptic vesicle exocytosis by fluorescence GABA imaging with single synapse resolution
- 2020 - 2022 Development of a fluorescent GABA probe for analysis of pathological mechanism in autism spectrum disorder
- 2015 - 2017 In vivo imaging of astrocytic glutamate dynamics in the brain
- 2011 - 2013 中枢神経系におけるD-セリンの時空間動態の可視化解析
Papers (8)：
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Nami Kitajima, Kenji Takikawa, Hiroshi Sekiya, Daisuke Asanuma, Hirokazu Sakamoto, Shigeyuki Namiki, Masamitsu Iino, Kenzo Hirose. In vivo Fluorescence Imaging of Extracellular ATP in the Mouse Cerebral Cortex with a Hybrid-type Optical Sensor. Bio-protocol. 2021. 11. 11. e4046
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Nami Kitajima, Kenji Takikawa, Hiroshi Sekiya, Kaname Satoh, Daisuke Asanuma, Hirokazu Sakamoto, Shodai Takahashi, Kenjiro Hanaoka, Yasuteru Urano, Shigeyuki Namiki, et al. Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor. eLife. 2020. 9
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Hirokazu Sakamoto, Tetsuroh Ariyoshi, Naoya Kimpara, Kohtaroh Sugao, Isamu Taiko, Kenji Takikawa, Daisuke Asanuma, Shigeyuki Namiki, Kenzo Hirose. Synaptic weight set by Munc13-1 supramolecular assemblies. Nature Neuroscience. 2018. 21. 1. 41-55
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Kenji Takikawa, Daisuke Asanuma, Shigeyuki Namiki, Hirokazu Sakamoto, Tetsuro Ariyoshi, Naoya Kimpara, Kenzo Hirose. High-throughput development of a hybrid-type fluorescent glutamate sensor for analysis of synaptic transmission. Angewandte Chemie - International Edition. 2014. 53. 49. 13439-13443
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Daisuke Asanuma, Yousuke Takaoka, Shigeyuki Namiki, Kenji Takikawa, Mako Kamiya, Tetsuo Nagano, Yasuteru Urano, Kenzo Hirose. Acidic-pH-activatable fluorescence probes for visualizing exocytosis dynamics. Angewandte Chemie - International Edition. 2014. 53. 24. 6085-6089
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MISC (15)：
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Kenji Takikawa, Hiroshi Sekiya, Kaname Satoh, Miki Takagi, Nami Kitajima, Kazunori Kanemaru, Hirokazu Sakamoto, Shigeyuki Namiki, Toshiko Yamazawa, Kenji Tanaka, et al. In vivo imaging of cerebral extracellular ATP dynamics. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S193-S193
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Kenji Takikawa, Hiroshi Sekiya, Kaname Satoh, Nami Kitajima, Miki Takagi, Hirokazu Sakamoto, Shigeyuki Namiki, Toshiko Yamazawa, Kenji Tanaka, Kenzo Hirose, et al. Use of a novel optical ATP probe for in vivo visualization of extracellular ATP wave during cortical spreading depression. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2015. 128. 3. S192-S192
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Kaname Satoh, Hiroshi Sekiya, Kenji Takikawa, Hirokazu Sakamoto, Tetsuro Ariyoshi, Shigeyuki Namiki, Kenji Tanaka, Kenzo Hirose, Masamitsu Iino. In vivo fluorescence imaging of extracellular ATP in cerebral cortex. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 210P-210P
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Kenji Takikawa, Shigeyuki Namiki, Hirokazu Sakamoto, Testuro Ariyoshi, Naoya Kinpara, Daisuke Asanuma, Kenzo Hirose. Development of a glutamate optical sensor for visualizing synaptic transmission. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 178P-178P
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佐藤要, 関谷敬, 瀧川健司, 坂本寛和, 有吉哲郎, 並木繁行, 廣瀬謙造, 飯野正光. 大脳皮質における細胞外ATPのin vivo蛍光イメージング. 日本薬理学会関東部会プログラム・要旨集. 2013. 129th
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Books (1)：
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生体の科学 68巻5号(2017年10月)
医学書院 2017
Education (1)：
- - 2014 The University of Tokyo Graduate School of Medicine
Professional career (1)：
Work history (6)：
Awards (3)：
- 2020/06 - 地方独立行政法人東京都健康長寿医療センター 令和2年度理事長研究奨励賞
- 2012/09 - 応用薬理研究会 第14回 応用薬理シンポジウム 最優秀賞
- 2010/12 - 東京大学 グローバルCOE「疾患のケミカルバイオロジー教育研究拠点」第3回リトリート 優秀ポスター賞
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