Rchr
J-GLOBAL ID：202101000050971230
Update date: Jan. 30, 2024
KOBAYASHI MASAHISA
コバヤシ マサヒサ | KOBAYASHI MASAHISA
Affiliation and department：
Job title：
Associate Professor
Research theme for competitive and other funds (4)：
- 2009 - 2011 Anti-CD3 antibody induced immune tolerance to infused enzyme in enzyme replacement therapy for lysosomal storage disease
- 2007 - 2008 Immune tolerance induction in enzyme replacement therapy for lysosomal storage diseases
- 2004 - 2005 ゴーシェ病の中枢神経症状発現機序及び治療に関する研究
- 2003 - 2005 脳血管関門を通過する酵素製剤の開発に関する研究
Papers (16)：
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Kenichi Hongo, Toru Harada, Eiko Fukuro, Masahisa Kobayashi, Toya Ohashi, Yoshikatsu Eto. Massive accumulation of globotriaosylceramide in various tissues from a Fabry patient with a high antibody titer against alpha-galactosidase A after 6 years of enzyme replacement therapy. Molecular genetics and metabolism reports. 2020. 24. 100623-100623
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Masahisa Kobayashi, Junko Matsuda, Hideo Sasai, Nobuyuki Ishige, Toya Ohashi, Hiroyuki Ida. Genetic studies of Japanese cases with high C5-OH level in newborn screening. 2020. 30. 1. 53-57
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Satoshi Morimoto, Ayumi Nojiri, Eiko Fukuro, Ikuko Anan, Makoto Kawai, Ken Sakurai, Masahisa Kobayashi, Hiroshi Kobayashi, Hiroyuki Ida, Toya Ohashi, et al. Characteristics of the Electrocardiogram in Japanese Fabry Patients Under Long-Term Enzyme Replacement Therapy. Frontiers in cardiovascular medicine. 2020. 7. 614129-614129
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Masahisa Kobayashi, Toya Ohashi, Eiko Kaneshiro, Takashi Higuchi, Hiroyuki Ida. Mutation spectrum of α-Galactosidase gene in Japanese patients with Fabry disease. Journal of Human Genetics. 2019. 64. 7. 695-699
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Kenichi Hongo, Keiichi Ito, Taro Date, Ikuko Anan, Yasunori Inoue, Satoshi Morimoto, Kazuo Ogawa, Makoto Kawai, Hiroshi Kobayashi, Masahisa Kobayashi, et al. The beneficial effects of long-term enzyme replacement therapy on cardiac involvement in Japanese Fabry patients. MOLECULAR GENETICS AND METABOLISM. 2018. 124. 2. 143-151
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MISC (7)：
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小林 正久, 笹井 英雄, 深尾 敏幸, 石毛 信之, 大橋 十也, 井田 博幸. 新生児マススクリーニングでC5-OH持続高値例の遺伝子型についての検討. 日本マス・スクリーニング学会誌. 2019. 29. 2. 187-187
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尾形 仁, 小林 正久, 金城 栄子, 樋口 孝, 衞藤 義勝, 大橋 十也, 井田 博幸. 日本人ファブリー病患者の遺伝子変異と臨床病型の相関についての研究. 日本先天代謝異常学会雑誌. 2016. 32. 140-140
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Ken Takagi, Masahisa Kobayashi, Masako Fujiwara, Toya Ohashi, Kiyoshi Ogawa, Yoshikatsu Eto, Hiroyuki Ida. Cardiac Characteristics of Fabry Disease in Japanese Children and Adolescents (Original). Jikeikai medical journal. 2014. 61. 4. 65-75
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樋口 孝, 小林 正久, 金城 栄子, 嶋田 洋太, 安藤 理恵, 小林 博司, 大竹 明, 黒柳 秀人, 井田 博幸, 大橋 十也. MLPAならびにGLA cDNAを用いたAnderson-Fabry病のα-galactosidase A遺伝子の変異解析. 日本先天代謝異常学会雑誌. 2014. 30. 176-176
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M. Kobayashi, T. Ohashi, T. Fukuda, Y. Eto, H. Ida. The clinical, genetic and pathological studies of 5 Japanese patients with perinatal lethal Gaucher disease. JOURNAL OF INHERITED METABOLIC DISEASE. 2008. 31. 95-95
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Education (1)：
- 1990 - 1996 Jikei University Faculty of Medicine
Awards (1)：
Association Membership(s) (6)：
日本小児神経学会
, 日本新生児成育医学会
, 日本周産期新生児医学会
, 日本人類遺伝学会
, 日本先天代謝異常学会
, 日本小児科学会
