Rchr
J-GLOBAL ID：202101000362874223
Update date: Oct. 12, 2024
Tsuboguchi Shintaro
ツボグチ シンタロウ | Tsuboguchi Shintaro
Affiliation and department：
Job title：
Assistant Professor
Research keywords (2)：
ALS (Amyotrophic lateral sclerosis)
, spreading of TDP-43, propagation of TDP-43
Research theme for competitive and other funds (2)：
- 2023 - 2026 ALS系統変性の時空間的進展:臨床と病理の相関から探求する病態機序
- 2022 - 2025 TDP-43の伝播仮説の包括的検証ー上位運動神経から筋肉までの順行・逆行経路ー
Papers (13)：
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Qiannan Wang, Shintaro Tsuboguchi, Kouichirou Okamoto, Mari Tada, Akiyoshi Kakita, Kazuo Nakamichi, Makoto Oishi, Masato Kanazawa, Osamu Onodera. Case report: Progressive multifocal leukoencephalopathy cooccurring with neurosarcoidosis: early brain biopsy and appropriate therapy for PML resulted in a favorable prognosis. Frontiers in Immunology. 2024. 15. 1447992
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Masahiro Hatakeyama, Takeshi Kanayama, Saori Tokunaga, Toshiya Kizaki, Shintaro Tsuboguchi, Masato Kanazawa, Osamu Onodera. A case of isolated dystextia due to subcortical infarction: a novel condition of digital device era. BMC Neurology. 2024. 24. 1. 374
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Shin Koide, Shintaro Tsuboguchi, Shingo Koide, Itaru Ninomiya, Taiki Saito, Takanobu Ishiguro, Etsuji Saji, Yo Higuchi, Takeshi Ikeuchi, Makoto Oishi, et al. A patient with neuronal intranuclear inclusion disease developed encephalitis-like symptoms after cerebral angiography. Neurology and Clinical Neuroscience. 2024
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Genri Toyama, Shintaro Tsuboguchi, Kazuya Igarashi, Etsuji Saji, Takuya Konno, Osamu Onodera. A case report of reversible cerebral vasoconstriction syndrome with thunderclap headache significantly exacerbated in the supine position and alleviated in the standing position. BMC neurology. 2023. 23. 1. 348
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Shintaro Tsuboguchi, Yuka Nakamura, Tomohiko Ishihara, Taisuke Kato, Tokiharu Sato, Akihide Koyama, Hideki Mori, Yuka Koike, Osamu Onodera, Masaki Ueno. TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models. Acta Neuropathologica. 2023. 146. 4. 611-629
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MISC (30)：
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Shintaro Tsuboguchi, Osamu Onodera, Masaki Ueno. ALSにおける異常タンパク質の伝播 TDP-43による運動神経回路内の病態の進行. Farumashia. 2024. 60. 5. 393-397
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大橋凌也, 林良太, 鈴木紗也佳, 筒井由夏, 加勢夕季乃, 富井光一, 阿部理一郎, 坪口晋太朗, 北澤勝, 曽根博仁. 下垂体炎に伴う中枢性尿崩症により生じた二次性後天性全身性無汗症の1例. 日本皮膚科学会雑誌. 2024. 134. 5
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畠山公大, 金山武史, 徳永沙緒里, 木崎利哉, 坪口晋太朗, 金澤雅人, 小野寺理. 左大脳皮質下梗塞により純粋dystypia,純粋dystextiaを呈した1例. 高次脳機能研究. 2024. 44. 1
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畠山祐樹, 坪口晋太朗, 石黒敬信, 佐治越爾, 畠山公大, 島田斉, 金澤雅人, 小野寺理. 発作性の神経症状を繰り返し,多発する微小出血像を認めた硬膜移植歴を有する39歳男性例. 臨床神経学(Web). 2023. 63. 9
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王倩楠, 坪口晋太朗, 木崎利哉, 小出伸, 山岸拓磨, 佐治越爾, 石黒敬信, 金澤雅人, 小野寺理. 進行性多巣性白質脳症に神経サルコイドーシスを合併した65歳女性. 神経治療学(Web). 2023. 40. 6
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Lectures and oral presentations (1)：
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TDP-43-induced antero- and retrograde degeneration and propagation in the corticospinal circuits in mouse ALS models.
(2024)
Education (3)：
- 2017 - 2021 Niigata University Graduate School of Medicine and Dental Sciences
- 2006 - 2012 University of Fukui School of Medical Sciences
- 2003 - 2006 福井県立藤島高等学校
Professional career (1)：
Work history (2)：
- 2022/04 - 現在 Brain Research Institute, Niigata University Department of Neurology Assistant Professor
- 2021/04 - 2022/03 Niigata University Medical and Dental Hospital Department of Neurology Assistant Professor
Awards (2)：
- 2024/11 - Niigata University Niigata University President's Award
- 2024/09 - Niigata University Niigata University Outstanding Paper Award TDP-43 differentially propagates to induce antero-and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
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