Rchr
J-GLOBAL ID：202101001179766442
Update date: Feb. 01, 2024
Kusakizako Tsukasa
クサキザコ ツカサ | Kusakizako Tsukasa
Affiliation and department：
Research field (1)：
Structural biochemistry
Research theme for competitive and other funds (4)：
- 2022 - 2024 聴覚や平衡感覚に関わる機械刺激-電気信号変換の構造基盤の解明
- 2019 - 2024 Time-resolved XFEL crystallography and rational engineering of light-driven proteins
- 2020 - 2022 機械刺激感受性チャネルTMCタンパク質の構造機能解析
- 2014 - 2017 Bam複合体による外膜タンパク質形成の構造基盤の解明
Papers (33)：
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Satoshi N Omura, Ryoya Nakagawa, Christian Südfeld, Ricardo Villegas Warren, Wen Y Wu, Hisato Hirano, Charlie Laffeber, Tsukasa Kusakizako, Yoshiaki Kise, Joyce H G Lebbink, et al. Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nature structural & molecular biology. 2023. 30. 8. 1172-1182
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Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Atsuhiro Tomita, Michihiro Nishimura, Kazuhiro Sawada, Hiroyuki H Okamoto, Suzune Hiratsuka, Gaku Nakamura, Riku Kuwabara, et al. Class B1 GPCR activation by an intracellular agonist. Nature. 2023. 618. 7967. 1085-1093
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Ryoya Nakagawa, Hisato Hirano, Satoshi N. Omura, Suchita Nety, Soumya Kannan, Han Altae-Tran, Xiao Yao, Yuriko Sakaguchi, Takayuki Ohira, Wen Y. Wu, et al. Cryo-EM structure of the transposon-associated TnpB enzyme. Nature. 2023
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Haon Futamata, Masahiro Fukuda, Rie Umeda, Keitaro Yamashita, Atsuhiro Tomita, Satoe Takahashi, Takafumi Shikakura, Shigehiko Hayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, et al. Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature Communications. 2022. 13. 6208
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Ryoya Nakagawa, Soumya Kannan, Han Altae-Tran, Satoru N Takeda, Atsuhiro Tomita, Hisato Hirano, Tsukasa Kusakizako, Tomohiro Nishizawa, Keitaro Yamashita, Feng Zhang, et al. Structure and engineering of the minimal type VI CRISPR-Cas13bt3. Molecular cell. 2022. 82. 17. 3178-3192
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MISC (11)：
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小林 和弘, 川上 耕季, 草木迫 司, 郷野 弘剛, 富田 敦弘, 小林 幹, 志甫谷 渉, 山下 恵太郎, 西澤 知宏, 加藤 英明, et al. PTH1受容体における内在性リガンドの認識機構と構造ダイナミクス. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-07
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Okamoto Hiroyuki, Miyauchi Hirotake, Inoue Asuka, Raimondi Francesco, Tsujimoto Hirokazu, Kusakizako Tsukasa, Shihoya Wataru, Yamashita Keitaro, Suno Ryoji, Nomura Norimichi, et al. クライオ電子顕微鏡によるヒト由来メラトニン受容体シグナル伝達複合体の立体構造解析(Cryo-EM structure of the human MT1-Gi signaling complex). 生物物理. 2022. 62. Suppl.1-2. S347-S347
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小林和弘, 川上耕季, 草木迫司, 郷野弘剛, 富田敦弘, 小林幹, 志甫谷渉, 山下恵太郎, 山下恵太郎, 西澤知宏, et al. PTH1受容体における内在性リガンドの認識機構と構造ダイナミクス. 日本生化学会大会(Web). 2022. 95th
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Kazuhiro Kobayashi, Kawakami Kouki, Kusakizako Tshukasa, Gono Hirotake, Tomita Atsuhiro, Kobayashi Kan, Shihoya Wataru, Yamashita Keitaro, Nishizawa Tomohiro, Kato Hideaki, et al. Structural transition of human PTH1R revealed distinct molecular recognition and molecular switch for sustainable activation. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 2-YIA-66
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岡本紘幸, 宮内弘剛, 井上飛鳥, RAIMONDI Francesco, 辻本浩一, 草木迫司, 志甫谷渉, 山下恵太郎, 山下恵太郎, 寿野良二, et al. ヒトメラトニン受容体シグナル伝達複合体のクライオ電子顕微鏡による単粒子解析. 日本生化学会大会(Web). 2021. 94th
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Education (3)：
- - 2017 The University of Tokyo Graduate School of Science Department of Biological Sciences
- - 2014 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
- - 2012 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
Work history (5)：
- 2022/10 - 現在 科学技術振興機構 さきがけ研究者
- 2020/06 - 現在 The University of Tokyo Graduate School of Science Department of Biological Sciences
- 2019/04 - 2020/05 The University of Tokyo Graduate School of Science Department of Biological Sciences
- 2017/04 - 2019/03 The University of Tokyo Graduate School of Science Department of Biological Sciences
- 2014/04 - 2017/03 日本学術振興会 特別研究員-DC1
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