NASU Yusuke

ナスユウスケ | NASU Yusuke

Affiliation and department：
Job title： Assistant Research Fellow
Homepage URL (1)： https://www.chem.s.u-tokyo.ac.jp/campbell/

Research field (1)： Bioorganic chemistry

Research keywords (4)： Lactate , Biosensors , Fluorescent proteins , Protein engineering

Research theme for competitive and other funds (9)：

2024 - 2030 Analytical Technology for Mitochondrial Glucose Metabolism Switches Driving the Power of Life
2024 - 2027 超高性能定量的乳酸バイオセンサーの開発
2023 - 2026 大脳皮質視覚野臨界期の神経可塑性における乳酸代謝の寄与の解明
2022 - 2026 Live tissue clearing technology for unraveling neural metabolism in deep tissue
2023 - 2025 Capturing the neuronal circuit that induces fatigue-like state

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Papers (22)：

Ignacio Fernández-Moncada, Gianluca Lavanco, Unai B. Fundazuri, Nasrin Bollmohr, Sarah Mountadem, Tommaso Dalla Tor, Pauline Hachaguer, Francisca Julio-Kalajzic, Doriane Gisquet, Roman Serrat, et al. A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice. Nature Communications. 2024. 15. 1. 6842
Fu Chai, Hajime Fujii, Giang N. T. Le, Chang Lin, Keisuke Ota, Karl Matthew Lin, Lam M. T. Pham, Peng Zou, Mikhail Drobizhev, Yusuke Nasu, et al. Development of an miRFP680-Based Fluorescent Calcium Ion Biosensor Using End-Optimized Transposons. ACS Sensors. 2024. 9. 6. 3394-3402
Yusuke NASU. LACCO Series: Genetically Encoded L-Lactate Biosensors. Seibutsu Butsuri. 2024. 64. 3. 155-158
Saaya Hario, Giang N. T. Le, Hikaru Sugimoto, Kei Takahashi-Yamashiro, Suguru Nishinami, Hirofumi Toda, Selene Li, Jonathan S. Marvin, Shinya Kuroda, Mikhail Drobizhev, et al. High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate. ACS Central Science. 2024. 10. 402-416
Yusuke Nasu, Abhi Aggarwal, Giang N. T. Le, Camilla Trang Vo, Yuki Kambe, Xinxing Wang, Felix R. M. Beinlich, Ashley Bomin Lee, Tina R. Ram, Fangying Wang, et al. Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging. Nature Communications. 2023. 14. 1

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MISC (1)：

那須雄介, BENKE Alexandre, 荒川聡子, MANLEY Suliana, 清水重臣, 小澤岳昌. 超解像イメージングによる細胞死誘導ミトコンドリアタンパク質凝集体の分析法. 日本分析化学会年会講演要旨集. 2013. 62nd

Books (3)：

月刊細胞「乳酸バイオセンサーの開発」
ニューサイエンス社 2023
情報伝達物質をありのままに観察
化学同人 2022
先端の分析法新訂第2版
エヌ・ティー・エス 2022 ISBN:9784860437374

Education (3)：

2009 - 2015 The University of Tokyo Graduate School of Science Department of Chemistry
2006 - 2009 The University of Tokyo Faculty of Science Department of Chemistry
2005 - 2006 The University of Tokyo College of Arts and Sciences

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (6)：

2024/09 - 現在 Academia Sinica Institute of Biological Chemistry Assistant Research Fellow
2022/10 - 現在 Japan Science and Technology Agency PRESTO
2018/07 - 2024/08 The University of Tokyo Graduate School of Science Assistant professor
2017/10 - 2018/06 University of Alberta Department of Chemistry Postdoctoral fellow
2015/04 - 2017/09 Chugai Pharmaceutical Co., Ltd. (Roche Group) Ukima Research Laboratories Researcher

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Association Membership(s) (6)：

Japan Society for Immunology , The Japan Cencer Association , Society for Neuroscience , The Japan Society for Analytical Chemistry , The Chemical Society of Japan , The Japan Neuroscience Society

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